Award Data

DESCRIPTION (provided by applicant): The long-term objective of this work is to design bi-functional peptide-drug conjugates that specifically target leukocytes. The peptide sequences are derived from ICAM-1 and bind to LFA-1 on activated leukocytes. The

The goal of this SBIR Phase II project is to bring the demonstrated Gallium Nitride (GaN) microdisplay technology to industrial maturity and to final commercialization levels. The project's goal will be accomplished by further optimizing the microdisplay device structural design and fabrication process based on the demonstrative results obtained in Phase I. Based on high-efficiency semiconductor m ...

Natural flavor compounds find wide applications in the food, feed, cosmetic, chemical and pharmaceutical industry, and isoamyl acetate is an important flavor ester. In this research program, a low-cost process is proposed to convert glucose from renewable sources to isoamyl acetate using a high-yielding metabolically engineered E coli. Isoamyl acetate produced via chemical synthesis results in an ...

DESCRIPTION (provided by applicant): Paclitaxel has shown promise in the treatment of several types of cancers, including ovarian cancer. The long-term goals of this research are to design a formulation of paclitaxel that is effective in the treatment of cancer and exhibits no formulation related toxicity. The present set of studies utilizes the techniques of precipitation with compressed antisol ...

DESCRIPTION (provided by applicant): The purpose of this Phase I project is to test the feasibility of using an interactive multimedia (IM) format for delivering professional development to adults tutors and paraprofessionals who work with students with L

DESCRIPTION (provided by applicant): The purpose of this project is to design and pilot test a prototype interactive multimedia (IM) program for teaching social skills to youth with social-adjustment problems. The instructional program will be designed fo

A novel approach to conducting long-range surveillance using small unmanned air vehicles is proposed. The effort builds on the concepts developed and demonstrated in Phase I. This includes air vehicle technology, data links, flight operations, sensors and communications networks. A detailed work plan in presented. The effort will culminate in a demonstration of the proposed technologies.

A method for providing endurance enhancement for unmanned aerial vehicles based on atmospheric phenomena is presented. The proposed method allows the UAV to sense certain atmospheric phenomena, and adapt itself to exploit these phenomena. The Phase I effort consists of understanding the physics of such flight, and developing the control laws for enabling the UAV to exploit these atmospheric phenom ...

This Small Business Innovation Research (SBIR) Phase I project will develop and demonstrate a MEMS-scale integrated microfluidic fuel injector for small internal combustion engines to improve their efficiency. This will allow the use of these engines in small autonomous aircraft for long endurance science missions. The development of a high efficiency engine with a microfluidic fuel injector will ...

75853-Carbon cycle monitoring is a key component of the mission to understand global-scale climate change. In particular, there is a need to accurately measure atmospheric carbon dioxide levels at regular intervals, and at various altitudes and locations, using low cost and simple aerial platforms. This project will create and demonstrate an unmanned aerial vehicle (UAV) that will lift carbon mo ...