Award Data

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project is the development of potentially the first FDA-approved phage therapeutic, non-antibiotic remedy specifically designed for honeybees. This treatment has the potential to become the global gold standard for treating American Foulbrood, a devastating honey bee disease caused by the bacteria Paenibacill ...

This Small Business Innovation Research Phase I project will automate an experiential simulation learning lab by funding the technical conversion from what is essentially a hardwired product requiring a dedicated lab available to schools within a limited geographic area to a nationally available online product. Additionally, the funding will drive the technological innovation necessary to maintain ...

The broader impact/commercial potential of this project is its capability to create a positive impact on current and future wireless systems. Multifunctional reconfigurable antenna (MRA) technology targeted in this project enables a single antenna element to dynamically change its frequency band, radiation pattern and polarization properties, which directly impact the radio-frequency (RF) coverage ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project is to establish faster, less expensive, more accurate ways of determining the contents of biological samples leading to novel medical diagnostics, new drugs, and other new products beyond the reach of the current scientific methods that employ mass spectrometry. The project will develop technology tha ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project entails alleviation of a human eye condition that has obscured the scientific community for almost a century. Refractive eye error is the most pervasive condition affecting the ocular health of the U.S. population, across all ethnicities. Presbyopia, a widespread form of such refractive error, affects ...

This Small Business Innovation Research Phase I project will enable fast focusing and zoom in microscopy with an optomechanical system consisting of micro-electro-mechanical systems (MEMS) mirrors. The microscope add-on will enable fast 3D imaging in wide-field microscopes and increase focusing and zoom speeds by 100x when compared with conventional methods in confocal and multiphoton microscopy. ...

This SBIR Phase II project will benefit society by reducing the cost of manufacturing biologic pharmaceuticals and improving their quality, including pharmaceuticals that are currently too costly to manufacture because they target relatively small patient populations. In order to accelerate the availability of newly discovered drugs, the pharmaceutical industry and federal regulatory agencies have ...

This Small Business Innovation Research (SBIR) Phase II project will enable video-rate three-dimensional (3D) imaging within two-photon microscopes (2PMs) by developing novel deformable membrane mirror (DMM) technology for fast, precise focus control. As a subset of laser scanning microscopes (LSMs), 2PMs achieve very high spatial resolution by using a focused, high-power laser beam to excite fluo ...

This Small Business Innovation Research (SBIR) Phase I project proposes to investigate the feasibility of fabricating large-aperture, periodic ferroelectric domain gratings for quasi-phase matched laser frequency conversion. The key innovation in this effort is the use of low temperature hydrothermally grown potassium titanyl phosphate (LTH-KTP) as the nonlinear optical substrate material. Using L ...

This Small Business Innovation Research (SBIR) Phase II project will develop a ceramic hydrogen fuel appliance (CHFA) using ceramic microreactor modules (CMMs) using a low-cost, net-shape manufacturing process, and a new material, that was developed in the Phase I project. The new material developed was demonstrated to have excellent capability for cost-effective microfabri ...