Award Data

Electric vehicles, including hybrids in the nearer term, are the principal transportation technology by which the United States can become independent of foreign oil, can become energy independent overall, and can effect control over greenhouse emissions. For this to become reality, electric vehicle costs need to come down and performance needs to improve. For electric vehicle motors, the goals ...

ScienceTomorrow in collaboration with Dr. David C Joy, at the University of Tennessee Research is proposed to fabricate direct digital Quantitative Secondary Electron Detectors (QSED) for scanning electron microscopes (SEMs). If successful, commercial versions of the QSED would transform the SEM/STEM into a quantitative, metrological tool with enhanced capabilities that, in turn, would broaden re ...

The objective of lab-on-chip (LOC) is to integrate and perform multiple analytical processes on a microchip platform. So far, most LOC research has been focused on electrophoretic separations. Limited progress has been made on multi-process integration, due mainly to the lack of a robust and miniaturized pump that can deliver constant flow and be integrated with LOC devices. Microchip HPLC can and ...

In this Phase II program, improved performance SWIR sensors with extended wavelength response to 2.5 microns will be developed using two disruptive technologies, which Amethyst has successfully demonstrated in the Phase I program: unipolar barrier (e.g., nBn) detector structures, and defect passivation via hydrogenation. This two-pronged approach addresses the main performance limitation of extend ...

ABSTRACT: The ability to access high-quality training anywhere and anytime continues to grow in importance due to the complex nature of operational team environments. Training simulations that use virtual agents that respond and behave like live teammates enhance training and help achieve the train as you fight objective without requiring a complete team of human participants. However, the domain ...

This program will develop an ultra-high performance infrared detector manufacturing technology with improved performance and cost effectiveness, and reduced cooling requirements when compared to the best commercially available HgCdTe and InGaAs detectors. This will be accomplished using a two-pronged approach addressing both device design and materials. First, the conventional pn photodiode device ...

DESCRIPTION (provided by applicant): According to the National Survey of Drug Use and Health (NSDUH) of 2008, 7.2 million Americans are in need of treatment for Substance-Related Disorders (SRDs), and a large proportion of those need treatment for opiate pain reliever, heroin, and alcohol addiction. Naltrexone (NTX), an opioid antagonist, is currently used in oral tablet form to help maintain opio ...

Intramammary infection (a.k.a., mastitis) is the largest attributable cause of lost productivity, discarded milk, chronic morbidity, and prophylactic antibiotic use in the dairy industry. The majority of new infections are associated with the dry period, during which the udders are temporarily engorged with milk that often leaks from the teat ends. Furthermore, the three major agencies of the U.S. ...

DESCRIPTION provided by applicant The laboratory rat is a preferred rodent model in pre clinical drug studies Their larger size facilitates procedures otherwise difficult in mice includng studies using instrumentation blood sampling and surgeries and allows for ten times the amount of tissue collection Although rats are often more suitable than mice for pharmacological toxicological phy ...

DESCRIPTION: Incremental improvements in label free screening technologies over the past decade have not produced the capability necessary to support the changing needs of drug discovery programs. Persistent artifacts related to non-specific binding, promiscuous binding, precipitation, complex binding, tubing retention, aggregation, and sub-optimally designed platforms continue to hinder progress ...