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IN THIS PROJECT, THE FEASIBILITY OF COMBINING SONIC DRILLING AND CONE PENETRATION TECHNOLOGIES WILL BE EVALUATED AND A SET OF PRELIMINARY DESIGN DRAWINGS DEVELOPED. SONIC DRILLING TECHNOLOGY HAS RECENTLY BEEN DEMONSTRATED AT THE HANFORD SITE, WA. THE RESULTS OF THE DEMONSTRATION PROVED THAT SMALL DIAMETER MONITORING WELLS COULD BE INSTALLED TO THE DESIRED DEPTH IN A RAPID MANNER USING THIS TECHN ...

THE OBJECTIVE IS TO DEVELOP A MINIATURIZED SIX DEGREES-OF-FREEDOM (6D) TRACKING APPARATUS FOR USE WITH THREE DIMENSIONAL (3D) ULTRASOUND AND MEDICAL IMAGING EQUIPMENT. SUCH A TOOL COULD ENABLE CLINICIANS TO STUDY HUMAN ANATOMY AND BODILY FUNCTIONS IN THREE DIMENSIONS. IN PURSUIT OF THIS GOAL, RESEARCHERS AT THE UNIVERSITY OF WASHINGTON HAVE BUILT A PROBE FOR 3-D TRANSESOPHAGEAL ECHOCARDIOGRAPHY (T ...

There is presently a great deal of interest in defecting specific genetic mutations or variants thatcould provide information about an individual's predisposition to a wide variety of diseases, predict anindividual's sensitivity to specific chemicals or drugs, or be used as prognostic indicators for thetreatment of patients with diseases such as cancer. Despite the importance of monitoring such ge ...

This proposal describes the design and testing of new enzyme-based amperometric sensors for the neurochemically important species, choline, acetylcholine and glutamate. In these devices, the electrical communication between the flavin redox centers of an oxidase and an electrode is achieved via a network of donor-acceptor relays chemically bound to a highly flexible polymer. Because the electron t ...

The design, fabrication, and testing of a pump rig supported by a magnetic bearing system is described. This rig will boost pump technology by: (1) permitting accurate determination of impeller force and moment coefficients by electromagnetic impulse excitation, orbit control, and bearing force and displacement measurement during operation, and (2) use of control theory to suppress cavitation-surg ...

The current development of an electric power generation system for the More Electric Aircraft (MEA) is based on a low-risk extension of existing three-phase, switched reluctance machine (SRM) technology. This research program proposes to study an alternate two-phase SRM and its associated power-conditioning converter. By the nature of the proposed machine, it has 50% of its stator coils active at ...

A NEW TYPE NOISE REDUCTION TECHNIQUE (1) HAS OPENED THE OPPORTUNITY TO DETECT BOTH A SIGNAL WITH NEGATIVE SIGNAL TO NOISE RATIO AND RANDOM SIGNAL ON A LINE. THE IMPORTANT ADVANTAGE OF THIS TECHNIQUE OVER EXTERNAL ENVIRONMENT NOISE AS WELL AS AN INTERNAL BACKROUND NOISE. IT PROVIDES A REAL TIME DETECTION AT A WIDE FREQUENCY RANGE, THIS VERY EFFICENT AND INEXPENSIVE APPROACH TO IMPROVE THE SNR BY TH ...

In the area of clinical coagulation research, much attention is focused on the molecular eventswhich occur before, during, and after anticoagulant and antithrombotic therapies. For purposes ofmonitoring the safety, efficacy and long-term effects of such therapies, there exist a number ofcommercially available assays to assess the progression of the procoagulant and fibrinolytic responses.For examp ...

Factors V and VIII are procofactors which are essential components of the blood coagulationprocess. Deficiency in either of these proteins is associated with severe bleeding disorders, hemophiliaand para-hemophilia. Deficiency states of these proteins can be caused by their proteolytic inactivationby Activated Protein C (APC), a natural anticoagulant enzyme. Therapeutic intervention in hemophilia- ...