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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Micro-targeted Computerized Alcohol Misuse Intervention System for Health Care

    SBC: RESEARCH CIRCLE ASSOCIATES            Topic: NIAAA

    DESCRIPTION provided by applicant Alcohol misuse continues to pose a major burden for public health Screening and brief intervention for alcohol misuse in primary care settings has been recommended for decades and the evidence base supporting it in primary care is robust However many primary care providers do not intervene in alcohol misuse and those that do often fail to do so systematica ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Twist-Sensor: Novel microarrays for multiplex detection of drug resistance

    SBC: SCANOGEN INC.            Topic: NIAID

    DESCRIPTION provided by applicant Drug resistance is rapidly spreading among Gram negative bacteria seriously complicating the treatment of infected patients and increasing the risk of lethal outbreaks In particular carbapenem resistant Enterobacteriaceae CRE organisms associated with high mortality rate andgt have become prevalent worldwide During of long term acute car ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Automating mosquito microdissection for a malaria PfSPZ vaccine

    SBC: SANARIA INC.            Topic: NIAID

    DESCRIPTION Malaria causes andgt million clinical cases and million deaths annually is responsible for andgt loss of GDP in Africa and is a serious concern for travelers and military personnel A highly effective vaccine is desperately needed and radiation attenuated Plasmodium falciparum Pf sporozoites SPZ and non attenuated PfSPZ with chloroquine chemoprophylaxis ChemoProphylax ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Targeting endogenous sialidases for treatment of endotoxic shock

    SBC: Oncoimmune Inc            Topic: NIAID

    DESCRIPTION provided by applicant Despite the advance of antibiotics sepsis remains a major challenge to human health as both survival and incidence of severe sepsis have been largely unchanged in the last two decades It is therefore important to develop new therapeutic approaches We have recently reported that bacterial sialidases may serve as therapeutic targets for polybacterial sepsis H ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Therapeutic/preventive vaccination against MusPV

    SBC: PAPIVAX, LLC            Topic: NIAID

    DESCRIPTION provided by applicant While most human papillomavirus HPV infections are short lived a subset become chronic and can progress to malignancy with much greater frequency in HIV infected individuals Only a dozen andapos high riskandapos HPV types cause cancer but HPV alone is responsible for andgt of anal cancer head and neck cancer and of cervical cancer Further and ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Long-term anti-angiogenic activity of intravitreal ellipsoid particles for NVAMD

    SBC: Asclepix Therapeutics, Inc.            Topic: N

    DESCRIPTION provided by applicant Long term anti angiogenic activity of intravitreal ellipsoid particles for NVAMD Niranjan B Pandey Ph D PI Aleksander S Popel Ph D Co I Jordan J Green Ph D Co I Peter A Campochiaro M D Co I of subaward Project Summary Current therapies for wet age related macular degeneration AMD target vascular endothelial growth factors VEGFA and pla ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Novel microarrays for DNA genotyping in the presence of excess background DNA

    SBC: SCANOGEN INC.            Topic: 172

    DESCRIPTION provided by applicant DNA microarrays are a primary tool for DNA genotyping because of their capacity to detect multiple targets simultaneously However DNA microarrays require fluorescent labeling and long incubation steps which limit their applicability Furthermore DNA microarrays are not capable of detecting DNA targets in the presence of excess background DNA This capacity ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Therapy and Prophylaxis for Genital Tract Infection

    SBC: THERAPYX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Genital tract infection with Neisseria gonorrhoeae gonorrhea does not induce a state of specific protective immunity and can be acquired repeatedly Despite public health measures the disease persists at an unacceptably high frequency there is no vaccine against it and resistance even to the latest generations of antibiotics continues to emerge Recent fin ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. A Patient-Driven Rehabilitation System to Improve Upper Limb Amputee Outcomes

    SBC: Infinite Biomedical Technologies, LLC            Topic: NICHD

    DESCRIPTION provided by applicant A patient driven rehabilitation system to improve upper limb amputee outcomes The goal of our research program is to develop technological solutions that restore function for upper extremity amputees For these individuals one of the most promising developments in the past decade has been the introduction of fully dexterous terminal devices However an effe ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Laser Speckle Imaging Chip for Telehealth Applications

    SBC: Vasoptic Medical, Inc.            Topic: NIA

    DESCRIPTION provided by applicant There is a strong unmet need for a low cost and convenient technology that can assist researchers and healthcare personnel in gathering vascular data Such vascular imaging technology could assist in the short term clinica research on the diagnostics disease progression and effect of treatment prevention strategies ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health

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