List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Novel flavonoids as anti-inflammatory agents in alcoholism

    SBC: NAPROGENIX, INC.            Topic: NIAAA

    DESCRIPTION (provided by applicant): Flavonoids are ubiquitous secondary metabolites in plants with many known health benefits, which are mostly ascribed to their potent anti-oxidant activity. However, a search for novel nicotinic ligands, using high throughput pharmacological screening of a native plant extract library, and subsequently a pure flavonoid library, led to the highly surprising con ...

    SBIR Phase I 2014 Department of Health and Human Services
  2. Web-Based Training in Alcohol SBIRT for Youth Aged 9-18

    SBC: Oregon Center For Applied Science, Inc            Topic: NIAAA

    DESCRIPTION (provided by applicant): Underage alcohol consumption is a public health concern with numerous negative sequelae, including adoption of other risky behaviors (smoking, other drug use, at-risk sexual behavior, drinking and driving), increased rates of depression or suicidal ideation, poor academic achievement, and behavioral problems (delinquency, violence, crime). Adolescents who drink ...

    SBIR Phase I 2014 Department of Health and Human Services
  3. Mobile Intervention to Enhance Physical Activity in the Chronically Ill

    SBC: Oregon Center For Applied Science, Inc            Topic: NIA

    PROJECT SUMMARY This project aims to fill the urgent need for a safe and engaging intervention that promotes physical activity in a population of patients with chronic diseases (e.g., diabetes, asthma, osteoarthritis, and chronic heart failure). Compelling evidence suggests that physical activity is an effective therapeutic intervention for numerous chronic diseases. However, in spite of the wide ...

    SBIR Phase I 2014 Department of Health and Human Services
  4. Microfluidic screening devices for health-span extending drugs

    SBC: NEMAMETRIX, INC            Topic: NIA

    Aging, the progressive degeneration of body and mind, is a universal problem marked by a decline in tissue organization and function, and an increase in the likelihood of death. Progress in understanding the cellular and molecular basis of aging is rapidlyaccelerating, following the discovery that several well-known model organisms age in many of the same ways as humans. In addition to their contr ...

    SBIR Phase I 2014 Department of Health and Human Services
  5. Development and Commercialization of an Innovative Rapid HIV-1 Incidence Assay

    SBC: SEDIA BIOSCIENCES CORPORATION            Topic: NIAID

    DESCRIPTION (provided by applicant): The objective of this project is to develop a commercially viable point of care Rapid HIV-1 Incidence Assay and establish its suitability for determination of recency of HIV-1 infection in whole blood, plasma, serum specimens for epidemiological, research and surveillance purposes. It is further intended to determine the feasibility of the application of the as ...

    SBIR Phase I 2014 Department of Health and Human Services
  6. An effector memory T cell-based therapeutic cervical cancer vaccine

    SBC: TOMEGAVAX, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): The longterm goal of this project is to utilize cytomegalovirus (CMV) vectors carrying oncogenes of high risk human papillomaviruses (HPV) as novel therapeutic vaccines against cervical cancer. Although recently launched prophylactic vaccines protect against HPV infection, these VLP-based vaccines have not demonstrated significant benefit for individuals who a ...

    SBIR Phase I 2014 Department of Health and Human Services
  7. Rapid Point-of-Care Salivary Diagnostic for Periodontal Health

    SBC: INNOVATIVE DIAGNOSTICS, INC.            Topic: NIDCR

    DESCRIPTION (provided by applicant): The dental profession has searched for many years for additional real time chair-side measures to provide objective measures to aid in the monitoring of periodontal health and early diagnosis of disease. Research efforts have produced solid evidence that constituents present in saliva can provide important complimentary diagnostic information, and have the po ...

    SBIR Phase I 2014 Department of Health and Human Services
  8. Mobile App for Self Management of Comorbid Depression and Metabolic Syndrome

    SBC: Oregon Center For Applied Science, Inc            Topic: NIDDK

    PROJECT SUMMARY Depression and metabolic syndrome (MetS) are common chronic conditions that are debilitating to individuals and costly to employers and public and private payors.1-3 Unfortunately, they are often comorbid, each making the other more severe, more difficult to manage, and more costly.4-7 This project will create MoodJaunt, a mobile app designed to fill a well-known gap8-14 in the po ...

    SBIR Phase I 2014 Department of Health and Human Services
  9. Chitosan Gastrointestinal Hemostatic Dressing

    SBC: HemCon Medical Technologies Inc            Topic: NIDDK

    ? DESCRIPTION (provided by applicant): Non-variceal upper gastrointestinal bleeding (NVUGIB) is a major cause of morbidity and mortality worldwide. Incidence of NVUGIB in the US is 53 events per 100,000 adults, with approximately 160,000 hospital admissions annually. US treatment and prevention of NVUGIB continues to be a major medical emergency, costing 550-900 million dollars every year. Fai ...

    SBIR Phase I 2014 Department of Health and Human Services
  10. Chimeric Rats for Liver Humanization

    SBC: Yecuris Corporation            Topic: NIDDK

    DESCRIPTION (provided by applicant): Yecuris has developed an in vivo genetic selection system (the FRG KO mouse) that permits extensive humanization of murine liver by transplantation with human hepatocytes. This model has many potential commercial applications in drug development and testing, both in the in vivo and in vitro markets, .The mouse, however, is a small rodent and therefore the num ...

    SBIR Phase I 2014 Department of Health and Human Services

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government