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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. CLIA-waived Point of Care Test of Infection by Cocci, Blasto, and Histo

    SBC: LUCIGEN CORPORATION            Topic: N/A

    Human cytomegalovirus (CMV) infection causes more cases of congenital disease than 29 currently screened conditions in the US combined & several newborn screening disorders in EU countries. Congenital CMV infection rate is 0.7% in developed countries with 18% of infected newborns developing permanent hearing & vision loss, or intellectual disability (5,000 in the US each year). Ninety percent of ...

    SBIR Phase I 2014 Department of Health and Human ServicesCenters for Disease Control and Prevention
  2. Novel flavonoids as anti-inflammatory agents in alcoholism

    SBC: NAPROGENIX, INC.            Topic: NIAAA

    DESCRIPTION (provided by applicant): Flavonoids are ubiquitous secondary metabolites in plants with many known health benefits, which are mostly ascribed to their potent anti-oxidant activity. However, a search for novel nicotinic ligands, using high throughput pharmacological screening of a native plant extract library, and subsequently a pure flavonoid library, led to the highly surprising con ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Web-Based Training in Alcohol SBIRT for Youth Aged 9-18

    SBC: Oregon Center For Applied Science, Inc            Topic: NIAAA

    DESCRIPTION (provided by applicant): Underage alcohol consumption is a public health concern with numerous negative sequelae, including adoption of other risky behaviors (smoking, other drug use, at-risk sexual behavior, drinking and driving), increased rates of depression or suicidal ideation, poor academic achievement, and behavioral problems (delinquency, violence, crime). Adolescents who drink ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Mobile Intervention to Enhance Physical Activity in the Chronically Ill

    SBC: Oregon Center For Applied Science, Inc            Topic: NIA

    PROJECT SUMMARY This project aims to fill the urgent need for a safe and engaging intervention that promotes physical activity in a population of patients with chronic diseases (e.g., diabetes, asthma, osteoarthritis, and chronic heart failure). Compelling evidence suggests that physical activity is an effective therapeutic intervention for numerous chronic diseases. However, in spite of the wide ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Microfluidic screening devices for health-span extending drugs

    SBC: NEMAMETRIX, INC            Topic: NIA

    Aging, the progressive degeneration of body and mind, is a universal problem marked by a decline in tissue organization and function, and an increase in the likelihood of death. Progress in understanding the cellular and molecular basis of aging is rapidlyaccelerating, following the discovery that several well-known model organisms age in many of the same ways as humans. In addition to their contr ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Antifungal Compound Discovery from Metagenomes

    SBC: LUCIGEN CORPORATION            Topic: NIAID

    DESCRIPTION (provided by applicant): There is societal need for new compounds in our arsenal of defenses against fungal pathogens, many of which are increasingly resistant to existing therapeutics. The best possible source for new antifungal compounds withpotentially novel mechanisms of action is within natural environments, particularly soils, which have the greatest diversity of microbial life. ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Novel system for sensitive detection of botulinum neurotoxins

    SBC: ALPHA UNIVERSE LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): The existence of terrorist organizations around the world, along with their ability to recruit expertise from physicians and scientists, poses an increasing threat of bioterrorist attack to society. In order to reduce the consequences of such an attack or even prevent it, new systems for detection of biothreat agents are necessary. Currently existing express ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Development and Commercialization of an Innovative Rapid HIV-1 Incidence Assay

    SBC: SEDIA BIOSCIENCES CORPORATION            Topic: NIAID

    DESCRIPTION (provided by applicant): The objective of this project is to develop a commercially viable point of care Rapid HIV-1 Incidence Assay and establish its suitability for determination of recency of HIV-1 infection in whole blood, plasma, serum specimens for epidemiological, research and surveillance purposes. It is further intended to determine the feasibility of the application of the as ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. BAC Sudoku Sequencing Paradigm to Accelerate Metagenomic Natural Product Chemistr

    SBC: LUCIGEN CORPORATION            Topic: NCCIH

    DESCRIPTION (provided by applicant): There is societal need for new compounds in our arsenal of defenses against microbial pathogens, many of which are increasingly resistant to existing therapeutics. The best possible source for new antimicrobial compounds with potentially novel mechanisms of action is within natural environments, particularly soils, which have the greatest diversity of microbial ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Increased bioavailability of polyphenols through bacterial metabolism

    SBC: AGRO BIOSCIENCES, INC.            Topic: NCCIH

    DESCRIPTION (provided by applicant): Numerous preclinical studies have demonstrated multiple health benefits including anti- inflammatory, antioxidant, and chemopreventive effects of dietary polyphenols. These compounds are abundant in plants and have added to the health benefits of many fruits, such as raspberries, pomegranates, and strawberries. As aging population in the U.S. and other develope ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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