List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. AcetaSTAT Rapid Assay for Acetaminophen Liver Injury

    SBC: Acetaminophen Toxicity Diagnostics, LLC            Topic: 300

    DESCRIPTIONprovided by applicantAlthough acetaminophen is the most common drug for treating pain and feverand also the most common cause of life threatening drug induced liver damagethere are no tests that specifically diagnose a liver injury from an overdoseThe object of this grant is to complete the development of AcetaSTAT ran innovative new method to diagnose an acetaminophen overdoseThe new t ...

    STTR Phase II 2016 Department of Health and Human Services
  2. Enzyme replacement therapy for GM1 gangliosidosis lysosomal rare disease

    SBC: Biostratagies, LC            Topic: 107

    The goal of this SBIR proposal is to develop an effective enzyme replacement therapyERTfor patients suffering from GMGangliosidosis by applying a novel ERT enzyme lectin fusion delivery strategy developed at BioStrategies LC and by exploiting safetysupplyand cost advantages of a plant based ERT protein bio manufacturing systemGMGangliosidosis is a rare lysosomal disease affecting less thanpeople i ...

    SBIR Phase II 2017 Department of Health and Human Services
  3. Improving MPS I ERT Efficacy through Lectin-Mediated Delivery

    SBC: Biostratagies, LC            Topic: 101

    The long term goal of this project is to develop an improved ERT for MPS I patients with innovations that enhance ERT delivery and disease correction in hard to treat organs such as the brain while integrating safety and cost advantages of plant based bioproductionMPS I Syndrome is caused by genetic deficiencies in the lysosomal enzymeL iduronidaseIDUAWhile current ERT drug options for MPS I effec ...

    SBIR Phase II 2017 Department of Health and Human Services
  4. Development of Plant Derived Antibodies for Drugs Abuse

    SBC: INTERVEXION THERAPEUTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this combination Phase I / Phase II STTR project is to test the hypothesis that anti-drug monoclonal antibodies are a safe and effective therapy for the medical problems associated with phencyclidine (PCP) abuse. There are currently no specific medications for treating the medical problems caused by acute or chronic PCP abuse. Thus, long-lasting m ...

    STTR Phase II 2006 Department of Health and Human Services
  5. Development of Plant Derived Antibodies for Drugs Abuse

    SBC: INTERVEXION THERAPEUTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this combination Phase I / Phase II STTR project is to test the hypothesis that anti-drug monoclonal antibodies are a safe and effective therapy for the medical problems associated with phencyclidine (PCP) abuse. There are currently no specific medications for treating the medical problems caused by acute or chronic PCP abuse. Thus, long-lastin ...

    SBIR Phase II 2006 Department of Health and Human Services
  6. Targeted Nanoparticles of Bismuth Organo Complexes for Spectral CT Imaging of Cor

    SBC: Ocean Nano Tech LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Chest pain in patients presenting to the emergency department (ED) present a clinical dilemma: transfer for emergent coronary revascularization, admit overnight for cardiac telemetry and stress testing, or discharge home with medical follow-up. In this proposal, we hypothesize that a novel thrombus-specific Spectral Computed Tomography (Multicolored CT) nanopar ...

    STTR Phase I 2012 Department of Health and Human Services
  7. Portable Brain Injury Biomarker Detection System with Integrated Microdialysis Pr

    SBC: Sfc Fluidics, Inc.            Topic: 102

    DESCRIPTION provided by applicant Portable Brain Injury Biomarker Detection System with Integrated Microdialysis Probe Project Summary SFC Fluidics is developing a portable fully integrated and automated medical device for clinical monitoring of patients with severe brain injury The instrument will allow for automated detection of several small molecule biomarkers glucose glutamate lact ...

    SBIR Phase II 2014 Department of Health and Human Services
  8. Performance Enhanced Managed FPGA

    SBC: Space Photonics, Inc.            Topic: AF05149

    The Performance Enhanced Managed Field Programmable Gate Array (PEM-FPGA) is a system component that contains an FPGA, microprocessor, and security features, packaged within a Multichip Module (MCM) that provides important services, such as dynamic partial reconfiguration, defragmentation, secure bitstream decryption, and anti-tamper management. These features make this enhanced FPGA a sustainabl ...

    SBIR Phase II 2006 Department of DefenseAir Force
  9. Adduct Dipstick for Diagnosis of Acetaminophen Toxicity

    SBC: Acetaminophen Toxicity Diagnostics, LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): Acetaminophen (APAP) is the most commonly used drug for the treatment of pain and fever in the world today. In large doses, APAP causes acute liver failure and is the leading cause of acute liver failure in the US. Thecurrent laboratory test for the diagnosis of APAP toxicity, measurement of APAP levels in peripheral blood, is only effective in the first 24 ho ...

    STTR Phase II 2011 Department of Health and Human Services
  10. IGF OT IGF TO TARGET SPECIFIC MOLECULAR IMAGING AGENTS IN COMBINATION WITH EXISTING IMAGING MODALITIES TO DETECT HIGH RISK ATHEROSCLEROTIC PLAQUE

    SBC: Ocean Nano Tech LLC            Topic: DBDR

    Not Available

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government