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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Reducing Methadone's Arrhythmic potential

    SBC: ACADEMIC PHARMACEUTICALS            Topic: NHLBI

    DESCRIPTION (provided by applicant): Methadone is an important long-term maintenance therapy for drug addiction and currently is frequently used for analgesia. However, methadone prolongs the QT interval on the electrocardiogram and this increases risk for life threatening arrhythmias and has led to the FDA's placing a black box warning on methadone's label. Initial studies in our laboratory hav ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  2. SBIR Phase I:Microfabricated CMP Pad Conditioners with Controlled Diamond Geometrical Protrusions

    SBC: Advanced Diamond TechNologies, Inc.            Topic: NM

    This Small Business Innovation Research (SBIR) Phase I project aims to develop micro-fabricated diamond Chemical Mechanical Polishing (CMP) pad conditioners as a replacement of traditional grit-based conditioners for semiconductor and optical polishing. This project will utilize Chemical Vapor Deposition (CVD) based ultrananocrystalline diamond technologies to create a narrowly size-distributed a ...

    SBIR Phase I 2010 National Science Foundation
  3. Variable Speed Speech Synthesis

    SBC: ADVANCED MEDIA RESEARCH INC            Topic: N08149

    The main objective of this project is to develop technologies for variable speaking speed synthesis, or Text-to-Speech (TTS). A TTS system converts written text into spoken language. There are numerous commercial TTS systems; however, most systems do not allow for speed control of the output speech. In the simulation-based virtual training system, TTS systems are used to generate the voice of the ...

    SBIR Phase II 2010 Department of DefenseNavy
  4. Accelerated Discovery and Development of New Pain Therapeutics

    SBC: AESTUS THERAPEUTICS, INC.            Topic: NINDS

    DESCRIPTION (provided by applicant): Neuropathic pain is a common complication of cancer, diabetes mellitus, viral infections, and other causes. Although physicians currently employ a variety of treatments to manage moderate to severe neuropathic pain, including non-steroidal anti-inflammatory drugs, opioids, tricyclic antidepressants, anti- seizure medications, serotonin-norepinephrine reupta ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  5. A Flow Through Cell Counting Assay

    SBC: ALLIED INNOVATIVE SYSTEMS            Topic: NHLBI

    DESCRIPTION (provided by applicant): The long-term goal of the proposed research is to develop a novel quantitative flow through cell counting method for enumeration of CD4+ T lymphocytes in human blood. CD4 cell counts are needed to stage and monitor HIV-infected patients. In adults, the absolute number of CD4+ T cells per microlitre of blood has critical prognostic and therapeutic implications, ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  6. Robust and Efficient Anti-Phishing Techniques

    SBC: ALTUSYS CORP.            Topic: OSD10IA3

    This proposal details an ambitious effort to develop Hybrid Phishing Protection System (HPPS). HPPS is a novel heuristics-based protection system that employs three lines of defenses to provide automatic, high-accuracy, and low-latency phishing identifica

    SBIR Phase I 2010 Department of DefenseArmy
  7. Intrusion Detection System (IDS) With Automatic Signature Generation for Self Healing Networks

    SBC: ALTUSYS CORP.            Topic: A10013

    This proposal details an ambitious effort to develop Smart Host-Based Intrusion Detection System (SHIDS). The SHIDS supports self-healing, self-monitoring, self-diagnosing, self-hardening, and self-recovering network architecture after corruption by an attack by automatically creating malware fingerprints and alert messages to protect against variants of known threats as well as possible zero day ...

    SBIR Phase I 2010 Department of DefenseArmy
  8. Problem Conceptualization & Resolution of Network Problems in Tactical Environment

    SBC: ALTUSYS CORP.            Topic: A09150

    The methods that has been historically developed and fielded for alarm and fault management in traditional communications networks do not provide adequate operational assurance for complex ad hoc tactical networks, especially for unskilled and inadequately trained operational personnel. Work on tactical network operations management that is proposed under A09-150 will use a novel approach that int ...

    SBIR Phase I 2010 Department of DefenseArmy
  9. Adaptive Thermal Control Coating for Radiation Hardening of Spacecraft

    SBC: APPLIED MATERIAL SYSTEMS ENGINEERING, INC.            Topic: AF093071

    The purpose of this SBIR phase I proposal is to design and demonstrate the feasibility of processing the adaptive thermal control material system (TCMS) that is radiation hardened. Through this proposal the engineered TCMS for the space craft protection is envisioned for the needed survivability and better protection of the space assets and the investments. The goal here is to develop an adaptive ...

    SBIR Phase I 2010 Department of DefenseAir Force
  10. High-Emissivity Ceramic Matrix Composites for Hypersonic Airframes

    SBC: APPLIED THIN FILMS, INC            Topic: MDA09007

    New materials and processes are needed to achieve performance requirements of future ballistic missile defense systems (BMDS). Ever increasing demands on achievable speed and performance require thermally stable, lightweight and mechanically robust thermal protection systems to protect underlying structures from aerothermal heating, radiative heating, as well as impact from rain and other particul ...

    SBIR Phase I 2010 Department of DefenseMissile Defense Agency
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