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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. C-arm Fluoroscopy for Prostate Brachytherapy

    SBC: BURDETTE MEDICAL SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A technique is proposed for the development of an intraoperative, 3-dimensional registration of C-arm fluoroscopic images with spatially-registered ultrasound visualization and implant guidance of radioactive implants and on-line implant assessment during the procedure for treatment of prostate cancer. With present techniques using transrectal ultrasound guidan ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  2. Design & Synthesis of Novel Agents to Treat Amyloidosis

    SBC: Advanced Life Sciences, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The major goal of our proposed project is to advance the development of novel compounds for the treatment of amyloidosis and other protein aggregation diseases. Preliminary work demonstrated that two chalcones inhibited amyloid fibril formation, in vitro, and that further work is warranted. The amyloid diseases that arise from nonimmunoglobulin proteins includ ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  3. Potential Brain Therapeutics

    SBC: AMERICAN BIOTECHNOLOGY RESEARCH CORP            Topic: N/A

    DESCRIPTION (provided by applicant): Use of botanical products such as exogenous antioxidants has gained considerable momentum in the last few years in therapy of human degenerative diseases. Among these antioxidants, tumeric, neem, guggul, alpha-tocopherol, Beta-carotene, and ascorbic acid have been shown to have a special relevance in maintaining the redox e ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  4. Development of HTS Buffer Layers Using the ECONO Process

    SBC: APPLIED THIN FILMS, INC            Topic: N/A

    Under Phase I effort, Applied Thin Films, Inc. (ATFI) discovered a new process to deposit oxide buffer layers for HTS coated conductors that is economical, scalable, and has demonstrated excellent performance with YBCO films (current densities of 1MA/cm2). The process is called ECONO (Epitaxial Conversion to Oxide via Nitride Oxidation) which is now being considered as the primary contender for t ...

    SBIR Phase I 2003 Department of DefenseAir Force
  5. Development of HTS Buffer Layers Using the ECONO Process

    SBC: APPLIED THIN FILMS, INC            Topic: N/A

    Under Phase I effort, Applied Thin Films, Inc. (ATFI) discovered a new process to deposit oxide buffer layers for HTS coated conductors that is economical, scalable, and has demonstrated excellent performance with YBCO films (current densities of 1MA/cm2). The process is called ECONO (Epitaxial Conversion to Oxide via Nitride Oxidation) which is now being considered as the primary contender for t ...

    SBIR Phase II 2003 Department of DefenseAir Force
  6. High Emissivity Protective Cerablak Coatings for Metallic TPS

    SBC: APPLIED THIN FILMS, INC            Topic: N/A

    The proposed effort relates to the use of Cerablak?, an amorphous-based black oxide material, as a coating for protection of metallic thermal protection systems (TPS) to be used in reusable launch vehicles (RLVs). This material shows potential to be a coating that meets all of NASA?s requirements for TPS protection in a single material system. The basic technical requirements for a coating to prot ...

    SBIR Phase I 2003 National Aeronautics and Space Administration
  7. Cerablak Matrix CMCs for Next Generation Radomes

    SBC: APPLIED THIN FILMS, INC            Topic: N/A

    In this Phase I SBIR project, a low-cost oxide-oxide interface coating-free ceramic matrix composite (CMC) will be developed for radomes for next-generation high speed missiles. The innovative and key component of the CMC is a newly patented matrixmaterial (CerablakT) based on aluminum phosphate compositions. The key properties of CerablakT relevant to radome applications is its low dielectric c ...

    SBIR Phase I 2003 Department of DefenseNavy
  8. Optical Trapping

    SBC: Arryx, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Manipulation of objects on a microscopic scale can be done conveniently with a device known as a laser or optical tweezers. While laser trapping was originally devised for trapping Rayleigh particles (i.e. particles much less than the wavelength of the incident light) it's ability to manipulate biological particles such as macromolecules, viruses, microtubul ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  9. Molecular Manipulation with a Holographic Laser Tweezers

    SBC: Arryx, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Manipulation of objects on a microscopic scale can be done conveniently with a device known as a laser or optical tweezers. While laser trapping was originally devised for trapping Rayleigh particles (i.e. particles much less than the wavelength of the incident light) it's ability to manipulate biological particles such as macromolecules, viruses, microtuble ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  10. SBIR Phase I: Tissue Engineered Cartilage for Drug Discovery

    SBC: ARTICULAR ENGINEERING, LLC            Topic: N/A

    This Small Business Innovation Research (SBIR) Phase I project proposes to define methodology to facilitate the growth of engineered cartilage tissue for use in a multi-well culture system for drug discovery. Culture systems, which are currently available to study the affect of potential therapeutic factors in degenerative joint disease, are less than ideal for shedding light upon the anabolic an ...

    SBIR Phase I 2003 National Science Foundation
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