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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. An integrated mobile and web-based application for problem cannabis use

    SBC: Checkup and Choices LLC            Topic: NIDA

    The objective of this research project is to develop an integrated set of digital tools that will deliver a brief motivational interventionBMIfor young adult marijuana users across a variety of platformsWe havein four randomized clinical trialsdemonstrated the effectiveness of similar tech based interventions for problem drinkingThese interventions have been integrated into one comprehensive progr ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. A high throughput next generation sequencing (NGS) pipeline to generate high quality recombinant therapeutic antibodies

    SBC: Specifica Inc.            Topic: 100

    Abstract Therapeutic antibodies are used to treat many different diseasesincluding cancerauto immunityinfection and atherosclerosisThey are the fastest growing class of pharmaceuticalswith annual revenues of$B inOne of the most important methods to select therapeutic antibodies is by selection from vast antibody librariesHowevergood libraries are extremely challenging to produceand commercially av ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Overcoming Isoniazid Resistance in Tuberculosis with New Chemical Entitites

    SBC: SpinCeutica, Inc.            Topic: NCHHSTP

    Isoniazid resistance is a major problem worldwideespecially the high level resistance caused by ST KatG mutationWe have found a stable isotope substitution improves activity against this resistant strainwhile others have used long acyl hydrazides that also improve activityWe therefore hypothesize that combining long acyl chain hydrazides to drive ST KatG binding with our MIE enhancedacylC INH warh ...

    SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  4. Transdermal H2S Sensing Device for Monitoring Peripheral Artery Disease

    SBC: EXHALIX LLC            Topic: NHLBI

    Project Summary Abstract Peripheral artery diseasePADand small vessel diseaseSVDare the consequences of damage to the endothelial cells that line all vesselsboth leading to inadequate skin perfusion and end organ and limb damageIt is prevalent in diabetic patient population in which nearlysuffers from PAD and SVDThe proposed effort addresses an unmet need for early diagnosis of PAD and SVD in this ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. A Novel Immunotherapy Targeting Cancer Stem Cells for the Treatment of Triple-Negative Breast Cancer

    SBC: Agilvax, Inc.            Topic: 102

    Agilvax s AXis an Immunotherapy for Triple Negative Breast CancerAgilvax is developing cancer immunotherapies and vaccines with its proprietary virus like particleVLPplatform technologyAgilvax s lead productAXis an immunotherapy for triple negative breast cancerTNBCtargeting cancer stem cellsCSCthat is designed for use in combination with existing and emerging therapiesTNBC is extremely aggressive ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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