Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Field Portable Instrument for Iodide Analysis

    SBC: 2B TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Iodine deficiency disorder (IDD) has been identified by the World Health Organization as a serious global health problem affecting 740 million people in 130 countries. Iodine deficiency is the most common cause of preventable brain damage, with nearly 50 million people suffering some degree of IDD-related brain damage. IDD is preventable and treatable by iodiza ...

    SBIR Phase II 2008 Department of Health and Human Services
  2. SBIR TOPIC 252- NANOPILLAR PLATFORM FOR IMPROVING CANCER DIAGNOSIS

    SBC: ADA Technologies, Inc.            Topic: N/A

    Cancer biomarker detection and cancer proteomics and genomics research require analysis platforms that provide high sensitivity and high throughput. In phase I, we will develop a novel nano-enabled sensing platform that is based on metal nanopillar patterned surface on a continuous Au thin film. This platform provides dramatic sensitivity increase through the combination of fluorescent enhancement ...

    SBIR Phase I 2008 Department of Health and Human Services
  3. PLATELET-BASED NANOPARTICLE THERAPY FOR PROSTATE CANCER

    SBC: ANDROBIOSYS, INC.            Topic: N/A

    The goal of this proposal is to develop directed energy transfer methods for imaging, tissue ablation and release of therapeutic modalities targeted to the vasculature of prostate cancer. The platform technology is a freeze-dried human platelet (Stasix particles) that contains super paramagnetic iron oxide (SPIO) nanoparticles. The pre-clinical model for validation is the angiogenic human vasculat ...

    SBIR Phase I 2008 Department of Health and Human Services
  4. TOPIC 229: DEV. OF MOLECULAR PHARMACODYNAMIC ASSAYS FOR TARGET

    SBC: BIOO SCIENTIFIC CORPORATION            Topic: N/A

    The research will result in new kits for quantitative detection and monitoring of hypoxia inducible factor-1 alpha (Hif-1a), a promising cellular target protein for pharmacological intervention. During the Phase 1 project, monoclonal antibodies will be developed and used to create highly sensitive ELISA assays for Hif-1a. Mice immunized with peptides derived from Hif-1a will be used to produce hyb ...

    SBIR Phase I 2008 Department of Health and Human Services
  5. WEB-BASED CORE COMPETENCY TRAINING FOR COALITIONS

    SBC: COMMUNITY SYSTEMS GROUP, INC.            Topic: N/A

    The long-term objective ofthis project is to create a scalable, affordable training and support system for comunity anti-drug coalitions. While training on various elecments of coalition effectiveness is available, market studies (see below) show that coalitions find this training to be inconvenient, expensive, incomplete, piecemeal and unconnected to post-training support. Therefore, coalitions l ...

    SBIR Phase II 2008 Department of Health and Human Services
  6. USE OF IM CROSS-SECTION AND M/Z AS A UNIQUE IDENTIFIER OF LIPIDS and NEUROPEPTIDES

    SBC: Ionwerks, Inc.            Topic: N/A

    The magnitude and dynamic range of data being generated by the NIDA MALDI-IM-o-TOFMS molecular imaging spectrometer demands a new approach to bioinfomatics. We are now able to record the spatial location of most molecules on the surface of bio-sample and are attempting to develop techniques which would yield depth profiles into tissues or the interior of single cells.

    SBIR Phase I 2008 Department of Health and Human Services
  7. Robust Classification Methods for Categorical Regression

    SBC: MARTINGALE RESEARCH CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Improving statistical methods to provide better classification performance and new analytical capabilities for categorical regression would be invaluable to the medical and health care research communities. Categorical regression models (e.g., binary logistic, multinomial logistic) are used extensively to identify patterns of alcohol-related symptoms, screen f ...

    SBIR Phase II 2008 Department of Health and Human Services
  8. Novel bisphosphonates for multiple myeloma therapy

    SBC: MBC Pharma, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to further develop novel bisphosphonate conjugate MBC-11 as treatment for tumor-induced bone diseases such as those associated with multiple myeloma. MBC-11 is the anhydride formed be tween arabinocytidine (AraC)-5'-phosphate and etidronate and is the lead product of our proprietary technology which employs conjugates of know ...

    STTR Phase II 2008 Department of Health and Human Services
  9. Not Available

    SBC: MEDISPIN, INC.            Topic: N/A

    This Phase II SBIR project will take advantage of the medium of internet to create an online environment for senior researchers, junior faculty and fellow to work individually or collaboratively, within an institution or across institutions, in their pursuit of research development and training programs. The end product will be a sustainable infrastructure weaving together three components: 1) an ...

    SBIR Phase II 2008 Department of Health and Human Services
  10. TOPIC 55B: DEVELOPMENT OF TOOLS TO ENHANCE MENTAL HEALTH INTERVENTIONS AND SERVIC

    SBC: MEDISPIN, INC.            Topic: N/A

    The high level of unmet mental health needs of older adults in the United States, coupled with the anticipated huge growth in the number of older adults over the next decades, underscore the importance of developing and using effective approaches to improve access to care, quality of care, and patient outcomes. Evidence-based practices in mental health are an integral part of the plan to achieve t ...

    SBIR Phase II 2008 Department of Health and Human Services
US Flag An Official Website of the United States Government