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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Oligonucleotide Enzyme Surrogate (OnES)

    SBC: Accacia International LLC            Topic: CBD08108

    Historically organophosphorus compounds such as insecticides and nerve agents have been susceptible to decomposition by proteinaceous enzymes. Organophosphate hydrolases (OPH) represent a practical method to deactivate such compounds peripherally and on surfaces. However, when such organophosphates are ingested, the use of proteinaceous enzymes such as OPH can be problematic because of their tende ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  2. Ribozymes for In Vivo Degradation of G-Nerve Agents

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08108

    Given the possibility to administer prophylactic doses of protein bioscavengers inactivating OP nerve agents before they reach their acetylcholinesterase target, much attention has been given to proteins such as human butyrylcholinesterase and paraoxonase I. As small nucleic acid catalysts can exhibit triphosphoesterase activities, the identification of new molecules active against nerve agents w ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  3. Collective Protection for Military Working Dogs

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08103

    Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and accommodation of canine physiological and psychological comfort needs. The overall operational weight of th ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  4. MWIR Spatial Light Modulators for Hyperspectral Image Projectors

    SBC: BOULDER NONLINEAR SYSTEMS, INC.            Topic: N/A

    The proposed effort is to build a high resolution, high speed spatial light modulator (SLM) to be used in infrared (IR) spectral projectors. An IR spectral projector produces programmable spectra by dispersing light onto a programmable array, currently digital micromirror devices (DMDs), which either transmit or block selected components of the light. the light is then recombined to form complex s ...

    SBIR Phase I 2008 Department of CommerceNational Institute of Standards and Technology
  5. Extended Refreshable Tactile Graphic Display (with Linear Actuation Array)

    SBC: E L I A Life Technology Inc            Topic: N/A

    New innovative technology for the visually impaired has been developed by NIST. If commercialized, it would provide refreshable tactile graphical information to the visually impaired, enabling them to compete on a more equal footing in the workplace and the education system.

    SBIR Phase I 2008 Department of CommerceNational Institute of Standards and Technology
  6. Camouflaged liposome construct for efficient drug delivery across the blood-brain barrier

    SBC: Luna Innovations Incorporated            Topic: CBD08107

    A major obstacle to non-invasive treatment of brain injury and disease is the blood-brain barrier (BBB), which prevents many intravenously injected therapeutics from being taken into the brain. In this program, Luna Innovations and Virginia Tech propose to develop a novel liposome-based delivery system capable of delivering any of a variety of neuroprotective agents of use against organophosphate ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  7. CVD-based Polytype Controlled SiC Nanowire Growth

    SBC: GENESIC SEMICONDUCTOR INC.            Topic: N/A

    A novel chemical vapor deposition (CVD) based step-flow epitaxy process is proposed for controllable growth of SiC nanowires with high polytype integrity. SiC nanowires will be grown in a modified commercial high-temperature CVD reactor, used by industry for growing high-quality SiC epitaxial thin films. Different polytypes of SiC nanowires will be grown by choosing appropriate substrate materials ...

    SBIR Phase I 2008 Department of CommerceNational Institute of Standards and Technology
  8. Kilopixel Array Cryostat (KAC) System for Multi-Kilogram Transition Edge Sensor (TES) Arrays

    SBC: High Precision Devices, Inc.            Topic: N/A

    Identify and study candidate architectures for supporting and cooling massive (~5 Kg) arrays of transition edge sensors, achieving hold times for one week at temperatures below 100mK.

    SBIR Phase I 2008 Department of CommerceNational Institute of Standards and Technology
  9. Generic Adsorptive Carbon Residual Life Indicator

    SBC: MORPHIX TECHNOLOGIES, INC.            Topic: CBD07103

    Generic residual life indicator technology developed under PI effort will be matured through reduction of COTS items used in the breadboard design to a miniaturized brassboard system capable of detecting agent saturation front migration through a sorbent. The capability of this brassboard system to detect representative agents from several classes will be demonstrated along with the ability to pr ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  10. Blood Brain Barrier (BBB) Permeable Encapsulating Agents for Effective Delivery of CNS-active Agents

    SBC: Lynntech Inc.            Topic: CBD08107

    Drug transport in the central nervous system is highly regulated by the Blood-Brain Barrier (BBB). Most medicines, including many for treating cancer, Alzheimer’s, and stroke, do not meet essential criteria, such as lipophilicity and low molecular weight, required for appreciable transport into the brain. However, endogenous peptides, such as insulin or transferrin, and certain monoclonal anti ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
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