Award Data

A collaboration between Amethyst Research Inc., University Multispectral Laboratories (a government-owned, contractor-operated nonprofit corporation), and Teledyne Imaging Systems (a large defense contractor) proposes to develop/improve high-performance infrared sensors based on Type II, strained-layer superlattices (SLS). Such sensors offer (theoretical) advantages over state-of-the-art HgCdTe p ...

In Phase I we demonstrated a novel in-situ cleaning technique based on UV-activated surface reactions involving ozone and hydrogen to remove organic adsorbates and chemically-bonded impurities, e.g oxides, from the substrate surface. In Phase II the program will develop this process to significantly decrease the density of material defects in large-format, infrared, focal-plane arrays. Electrica ...

DESCRIPTION (provided by applicant): The Advanced Biofidelic Lower Extremity Kids prosthesis (ABLE Kids) project will advance the state-of-the-art of pediatric prosthesis systems by advancing the demonstrably successful Phase I device and refining it intoan ultracompact and lightweight form factor suitable for pediatric use. Through the support of the Shriner's Hospitals in Salt Lake City, U ...

DESCRIPTION (provided by applicant): Stiffness and alignment of ankle-foot orthoses (AFOs) should be tuned optimally to maximize their function. Improperly tuned AFO may induce joint pain, reduced ambulatory function, and increased medical complications for patients with stroke. Therefore, the relative quality of AFOs fit determined by its stiffness and alignment is of paramount concern in the d ...

DESCRIPTION (provided by applicant): Selexys Pharmaceuticals is developing a humanized monoclonal antibody drug called SelG1 directed against P-selectin for the treatment of vasoocclusive crisis in patients with sickle cell disease. The ultimate goal of this Phase IIB proposal is to further advance SelG1 into Phase II/III safety and efficacy trials to support of regulatory filings for FDA approval ...

This Small Business Innovation Research Phase I project proposes high specific strength composite sandwich panels using a new form of manufacturing, tailored for Amorphous Metal Honeycomb (AMH) cores. Previously it was impossible to form these alloys as honeycombs since they do not behave like crystalline metals. Yet, amorphous metals offer mechanical properties far beyond other materials. With th ...

The objective of lab-on-chip (LOC) is to integrate and perform multiple analytical processes on a microchip platform. So far, most LOC research has been focused on electrophoretic separations. Limited progress has been made on multi-process integration, due mainly to the lack of a robust and miniaturized pump that can deliver constant flow and be integrated with LOC devices. Microchip HPLC can and ...

This Small Business Innovation research Phase I proposes the development of a practical and reliable in-vitro test for detecting the evidence of Mycobacterium tuberculosis (MTB) infection as an alternative to the tuberculin skin test (PPD-TST) and to the interferon gamma release assays (IGRAs). The proposed methodology will be a powerful detection technology in clinical diagnosis owing to its dete ...

Improved performance SWIR sensors with extended wavelength response to 2.5 microns will be developed using two disruptive technologies with which Amethyst has demonstrated success: nBn detector structures and defect passivation via hydrogenation. Similar to conventional extended wavelength photodiodes, the improved sensors will based on mismatched InGaAs grown on graded buffer layers on InP substr ...

ABSTRACT: The engineer will be guided through the creation of criteria, alternatives and evaluation techniques in order to make a better decision. BENEFIT: The engineer will be guided through the creation of criteria, alternatives and evaluation techniques in order to make a better decision.