Award Data

Chemical warfare agents such as the lethal nerve agent soman are a major source of risk to military personnel. Currently, pyridostigmine bromide (PB) is the only FDA-approved pretreatment to counteract the effects of soman. The rationale behind PB administration is that it acts as a “temporary” inhibitor of AChE. This precludes nerve agents from irreversible inactivation of AChE, thereby mitig ...

To address the Chemical and Biological Defense (CBD) need for a field-portable mass spectrometer for small molecule drugs in clinical samples, Physical Optics Corporation (POC) proposes to develop a new FiEldable DRug Mass Analysis (FERMA) system based on a combination of portable mass spectrometry technology with laser desorption/ionization for use with aqueous clinical samples. The FERMA system ...

To address the CBD’s need for real-time analytical technology for multicomponent vapor identification and quantification, Physical Optics Corporation (POC) proposes to continue the development of a new Photoacoustic Gasses Optical Detector and Analyzer (PAGODA) autonomous, network-enabled photoacoustic spectrometer (PAS) for the correlation, analysis, and identification of measured spectra. In t ...

A program to develop a compact, MLA-based, LWIR, full-motion-video hyperspectral imager for chemical detection is proposed. The proposed Hyperspectral Chemical Imaging Sensor (HyCIS) builds upon Surface Optics’ real-time hyperspectral imaging activities, including our 3D full-motion-video spectral imaging (FMV-SI) technology and our MIDIS hyperspectral image processor. Simultaneously sampling 16 ...

SA Photonics is please to submit the proposal for the HawkEye compact LWIR hyperspectral imaging system. HawkEye leverages SA Photonics previous visible, SWIR, and LWIR programs to result in a compact, hand held, battery operated hyperspectral imager in a low cost design approach. Furthermore, HawkEye will leverages SA Photonics expertise in warfighter body worn equipment and ground troop personal ...

The use of continuous glucose monitors can be an invaluable management tool for patients afflicted by glycemic variability due to critical illness or trauma. Maintaining stable glucose levels enhances health and lowers care costs, and individuals equipped with continuous glucose data have significantly improved outcomes. Profusa has developed highly miniaturized, injectable, tissue-like, glucose s ...

As unmanned aircraft systems (UAS) become more prevalent there is an increasing desire to automate UAS navigation and control. To enable future UASs to perform a wider variety of missions, the they must be able to complete autonomous relative navigation to accomplish missions. Current technologies rely heavily on GPS measurements, which are undesirable since GPS signals may be unavailable in many ...

Rapid innovation in computer-mediated communication (e.g., social media) has created new channels for the spread of information. The proposed work will integrate Advanced Brain Monitoring’s neurological and physiological metrics (e.g., EEG, ECG, eye-tracking) with Cubic Intific Corporation’s Social Media Analytic Replication Toolkit (SMART) to yield a unified framework for analyzing informatio ...

Future TBCC propulsion systems, in addition to incorporatingvariablegeometricalenginefeatures,will require controllingtheengine duringits transient mode,as wellas,managingaerodynamicand thermal limits of thesystem over theentireflight range. Theimportantchallenges of TBCC enginesareto establish astablemodetransition process whilemaintaining propulsion system performanceand operability, perform ast ...

NextGen Aeronautics is proposing to develop and demonstrate a lightweight, low cost, load bearing, thermally protective and high temperature survivable structure for hypersonic flight. Our technical approach is based on advancing the work performed under legacy programs and Phase I to a higher maturity level. Creating a single structural element with inherent insulating properties provides signifi ...