Award Data

There is a significantunmet needand commercialization opportunity for small business worksite wellness programs that Vimcity can providethrough a mobile technology solutionVimcity offers an innovativecommunity based web and mobile platform application to overcome small business barriers to worksite wellnessBy connecting the workforce to health promoting resources through their webbased productVimc ...

Development of an agile device that can deliver supplies to and from remote locations during public health emergenciesIn the context of emergency public health responsedrones could be extremely useful for transporting necessary supplies to remote or inaccessible locationsSupplies might include dry goodsbut would certainly include clinical specimensreagent kitsvaccines and other perishable goodsThe ...

The purpose of this proposal is to develop an automated Auditory Brainstem ResponseABRbased neurological screening device and software module that will enhance the early detection of autism and other neurological conditionsAutism Spectrum DisordersASDhave an incidence rate ofBased onmillion births in the United States innew cases of ASD will be diagnosed from that birth cohort aloneThe practice of ...

PROJECT SUMMARY Genomic instabilityinduced by DNA damageand partly mitigated by DNA repair and antioxidantsplays a critical role in the pathogenesis of many major human diseasessuch as neurodegenerationcancer and cardiovascular diseasetogether with agingThere is a critical need for automated assays that can perform these assessmentsand bring them into greater routine usewhich will help advance our ...

Leadless cardiac pacemakersLCPsrepresent a revolutionary leap forward in cardiac pacing technology via its circumvention of transvenous leadsCurrent LCP lithium CFX batteries arecc resulting in an overallcc LCP deviceThis Phase I effort will demonstrate the feasibility of acc betavoltaic battery for LCPs with ayear lifetimex lifetime of current LCP batteriesenabling LCPs with a volumetric size ofc ...

Project Summary This SBIR Urgent Competitive Revision will develop the first affinity membrane to purify therapeutic mRNA with high selectivity and throughput. mRNA-based pharmaceuticals have potential to address a wide variety of pathologies. mRNA-based vaccines can increase safety and dramatically shorten development timelines in pandemic scenarios. A number of mRNA-based COVID-19 vaccines are u ...

ABSTRACT Despite the overefficacy of diabetic retinopathyDRtreatmentit continues to be the leading cause of blindness in working age AmericansOvermillion adults in the US have diabetesOf thesewill develop DR andwill develop vision threatening DRVTDRCurrentlyless than half of all patients with diabetes receive the recommended annual dilated eye exam andof those diagnosed with VTDRonlyundergo timely ...

PROJECT ABSTRACTThe electroencephalogramEEGis a sensitive and well established tool for detecting disturbances in brain functionEEG recordingseven as brief as just a few minutescan potentially provide useful information for patients with neurological or neuropsychiatric disordersHowevermost patient care settings are not able to offer EEG services due to the lack of equipment or personnel with the ...

Development of a Novel Bio Adhesive Mesh System for Abdominal Hernia Repair Project Summary Abstract This project proposes the development of a novel mesh adhesive system for abdominal hernia repair utilizing surface modification of polymer surgical mesh to allow for improved tissue fixation with a poloxamine hydrogel adhesiveMore thanmillion Americans undergo hernia repair with surgical mesh each ...

PROJECT SUMMARYHuman embryonic stem cellshEScrepresent a potentially unlimited supply of tissues for regenerative therapiesHowevercurrent differentiation methods result in heterogeneous populations of cells in which the desired product isat besta fraction of the totalMoreovercarry over undifferentiated cellsas well as cells that de differentiate upon transplantationhave been shown to form teratoma ...