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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Gap-Free Model-Based Engineering for Manufacturing and Analysis: Digital Thread without Translation

    SBC: Nvariate, Inc.            Topic: None

    Modern Model-Based Enterprise / Engineering (MBE) systems rely on freeform surfaces built as complex combinations of geometric primitives to define engineered objects. Unfortunately, the intersection of freeform surfaces in MBE applications results in highly approximated solutions, degrading models that cost billions annually by US industry to fix. Current technology limits the abilities of users ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  2. Direct Performance Evaluation of Additive Manufacturing Process Plans

    SBC: INTACT SOLUTIONS INC.            Topic: None

    Additive manufacturing is steadily advancing towards fulfilling its promise of customized and on-demand production of functional parts. However, performance of as-manufactured parts can differ significantly from the as-designed parts because the as-manufactured geometry differs from the as-designed geometry and the asmanufactured material properties are not known. Attempts to predict performance o ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  3. Advanced Manufacturing and Material Measurements Software Tool Weave ™ for the Acceleration and Automation of SEM Image Analysis in the Semiconductor Industry

    SBC: Sandbox Semiconductor Incorporated            Topic: None

    In this Phase I SBIR proposal, SandBox Semiconductor™ proposes to develop an Advanced Manufacturing and Material Measurements software tool called Weave ™ for accelerating and automating SEM image analysis for the semiconductor industry. During the development of a new manufacturing process line for a semiconductor device, tens of thousands of scanning electron microscopy (SEM) images are take ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  4. Multimode Chiroptical Spectrometer for Nanoparticle Characterization

    SBC: Applied Nanofluorescence LLC            Topic: None

    This project will develop a new scientific instrument optimized for the advanced characterization of near-infrared fluorescent nanoparticles that can exist as left- or right-handed structures (enantiomers). Single-walled carbon nanotubes (SWCNTs) are the leading current example of such nanomaterials. Applied NanoFluorescence, LLC (ANF) proposes a novel multi-mode chiroptical spectrometer that can ...

    SBIR Phase II 2019 Department of CommerceNational Institute of Standards and Technology
  5. DISTRIBUTED DATA MANAGEMENT FOR CANCER CLINICAL TRIALS

    SBC: American Power Jet Company            Topic: N/A

    THIS PROPOSAL SEEKS TO DEVELOP AND IMPLEMENT A DISTRIBUTED DATA MANAGEMENT NETWORK FOR CANCER CLINICAL TRIALS. THE NETWORK WILL BE MICROCOMPUTER BASED AND WILL HAVE AS ITS OBJECTIVE A CENTRALIZED DATABASE FOR MONITORING THE PROGRESSOF CLINICAL TRIALS. FEATURES WILL INCLUDE DATA ENTRY USING PREFORMATTED SCREENS, AUTOMATED ERROR CHECKING, EDITING FACILITIES, DATA SECURITY, AND DATA TRANSFER CAPABILI ...

    SBIR Phase I 1987 Department of Health and Human Services
  6. MOLECULAR ANALYSIS OF TK AND HPRT GENE MUTATIONS IN L5178Y MOUSE LYMPHOMA CELLS

    SBC: APPLIED GENETICS LABORATORIES            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  7. AUTOMATED ELECTROPHYSIOLOGIC HEARING SCREENING DEVICE

    SBC: Artificial Hearing Systems Cp            Topic: N/A

    HEARING TESTING OF NEWBORNS AND INFANTS USING AUDITORY BRAINSTEM RESPONSES (ABR) HAS GAINED WIDESPREAD ACCEPTANCE AND HAS COME TO BE PREFERRED OVER OTHER LESS ACCURATE TECHNIQUES. ABR'S STRENGTH IS ITS DIRECT MEASUREMENT OF AUDITORY FUNCTION, WHICH RESULTS IN HIGH TEST SPECIFICITY AND SENSITIVITY. CLINICAL USE OF ABR, HOWEVER, IS STILL LIMITED BECAUSE OF THE PROFESSIONAL LABOR-INTENSIVE OPERATION ...

    SBIR Phase II 1987 Department of Health and Human Services
  8. NEUROANATOMY WORKSTATION AND KNOWLEDGE ENGINEERING

    SBC: BIOGRAPHICS, INC.            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  9. DIMETHYLSUBERIMIDATE AS A PULPOTOMY AGENT

    SBC: Biomedical Development Corporation            Topic: N/A

    THE LONG-TERM GOAL OF THIS APPLICATION IS TO DEVELOP DIMETHYLSUBERIMIDATE (DMS) AS AN ALTERNATIVE PULP THERAPY. FORMOCRESOL, THE DRUG MOST COMMONLY USED FOR TREATMENT OF CARIOUSLY EXPOSED PULPS OF THE PRIMARY DENTITION, IS TOXIC TO THE TREATED TISSUE, INDUCES ANTIGEN FORMATION AND SUBSEQUENT CHRONIC INFLAMMATION, IS RAPIDLY DISTRIBUTED SYSTEMICALLY, AND HAS MUTAGENIC POTENTIAL. FORMOCRESOL PULPOTO ...

    SBIR Phase II 1987 Department of Health and Human Services
  10. LIPID POLYMER FILMS-A NOVEL BIOMATERIAL

    SBC: Biotechnology Associates Inc            Topic: N/A

    BIOTECHNOLOGY ASSOCIATES, INC. WILL DEVELOP SURFACE COATINGS COMPOSED OF FILMS OF POLYMERIZED LIPIDS THAT WILL BE NONTHROMBOGENIC AND NONADHESIVE FOR CELLS. THUS THEY MAY PROVIDE USEFUL BIOCOMPATIBLE COATINGS FOR BIOMEDICAL DEVICES. LIPID POLYMER FILMS WILL ALSO BE MODIFIED BY COUPLING OF ADHESION PROTEINS OR PEPTIDES TO PROVIDE SURFACES WITH CONTROLLED CELL ADHESION PROPERTIES IN THE ABSENCE OF S ...

    SBIR Phase I 1987 Department of Health and Human Services

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