Award Data

Our biosensor is made of silicon nanowire arrays functionalized with antibodies to measure the concentration of specific proteins. In this grant we will take a sensor that has been demonstrated for use in measuring a set of generic host cell proteins and we will apply the sensor to measure a set of proteins for a specific cell line. In doing so, we will demonstrate the utility of our sensor to be ...

This project will develop a new scientific instrument optimized for the advanced characterization of near-infrared fluorescent nanoparticles that can exist as left- or right-handed structures (enantiomers). Single-walled carbon nanotubes (SWCNTs) are the leading current example of such nanomaterials. Applied NanoFluorescence, LLC (ANF) proposes a novel multi-mode chiroptical spectrometer that can ...

Cost-effective and power-efficient radiation tolerant semiconductors are needed in various harsh environments, such as particle detectors, communication satellites, high-altitude avionics and medical imagining equipment. These include amplifiers, voltage regulators, analog-to-digital converters (ADCs) and digital logic circuitry. However, radiation-tolerant high-speed ADCs currently cost more than ...

There are an estimated 1.7 million oil and gas wells in the United States, 771,000 of these are considered marginal producers. Combined they make up 11.3% of the US oil production and 8.3% of the US gas production. In that last 10 years, over 131,000 of these oil wells and 48,000 gas wells have been plugged and abandoned. Most of these wells suffer from paraffin plugging problems. The only way to ...

The development of radiation detection materials would benefit with greater access to computational models that relate physical traits seen in manufacture with complex energy transitions occurring in the material that control operating performance. However, the HPC requirements behind these models remain beyond the reach of most businesses involved in this small yet vital field impacting National ...

Molten salts are a crucial component in the proposed advanced nuclear reactors called “molten salt reactors” (MSRs). The appealing aspect of an MSR is that a melt-down is virtually impossible, since the fuel is dissolved into the salt. One of the key challenges hindering MSRs is corrosion of structural materials that hold the molten salt due to the interactions between material and molten salt ...

A crucial step in understanding the physics of our universe, and a current priority for DOE’s Nuclear Physics program, is elucidating the nature of neutrinos. Experiments probing the nature of the neutrino are searching for the rare nuclear process of neutrinoless double-beta decay (0νββ). The state-of-the-art bolometer-based experiment is the Cryogenic Underground Observatory for Rare Events ...

As the United States aging fleet of nuclear reactors approach the end other their lifetimes, a new generation of nuclear reactors (Generation IV) are being developed to ensure national energy security without emissions or pollutants as a byproduct. However, there are many technological hurdles associated with the extreme corrosive environments required by molten salt reactor designs. This presents ...

For the foreseeable future, the Nation’s energy demand will continue to come largely from indigenous fossil energy resources and hydrocarbon fuels. Specifically waste coal plus other opportunity fuels need to be utilized as a feedstock to eliminate a waste stream and optimized to maximize energy yield and cleanly minimize pollutant emissions. Modular equipment is needed for installation in coal ...

Millions of dollars are spent every year in generating the tons of data that are necessary for addressing nuclear physics grand challenge problems at DOE facilities. Due to inherent technical and financial limitations at the “last- mile” of the data delivery pipeline, only a small fraction of these expensive Peta bytes of data is available for immediate access by end-users at any given time. T ...