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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Structure-based discovery of dopamine D1 receptor selective small molecule ligands

    SBC: CONFOMETRX, INC.            Topic: 101

    Dopamine receptors are a family of G protein coupled receptorsGPCRsand can be further divided into DlikeDand Dand DlikeDDand DsubfamiliesIn this proposalwe focus on Dreceptorwhich is widely expressed in brain at high levelsModulation of Dactivity is implicated in the treatment of many psychiatric and neurological disorderssuch as schizophreniaattention deficit hyperactivity disorderdepressionParki ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. SBIR Phase II: OCT-Compatible Imaging Adaptor for Precision Vascular Access via Hollow-Bore Needles

    SBC: WEST FACE MEDICAL DEVICES, INC.            Topic: BM

    This SBIR Phase II project supports development of a commercially viable real time optical imaging device to address the problem of failed first time vascular access. Peripheral IV access (PIV) is the most common invasive procedure for all ages, races and clinical settings. In the United States alone, there are an estimated 230 million PIVs placed per year. First time IV access has a shockingly hi ...

    SBIR Phase II 2019 National Science Foundation
  3. Compact Raman Fiber Optic Probe with Inline Spectral Filtering

    SBC: Nikira Labs Inc.            Topic: None

    In this Small Business Innovative Research (SBIR) effort, Nikira Labs Inc. proposes to develop a compact Raman fiber optic probe with inline spectral filtering that improves fiber-coupled Raman measurements by filtering out Raman scattering from the excitation fiber and elastically scattered laser light from the collection fibers. The technology will enable compact fiber probes for Raman studies i ...

    SBIR Phase II 2019 Department of CommerceNational Institute of Standards and Technology
  4. SBIR Phase II: The Reinvention Of The Wheel. For Agricultural Uses and Beyond.

    SBC: Shark Wheel, Inc.            Topic: OT

    This SBIR Phase II project will explore the potential benefits of a sine wave shaped wheel compared to a traditional circular wheel for the central pivot irrigation industry. The central pivot irrigation industry is an essential segment of the agriculture industry and this project aims to deliver a superior wheel that solves the persistent issue of trench-digging that leads to equipment breakdown, ...

    SBIR Phase II 2019 National Science Foundation
  5. SBIR Phase II: Large Arrays for 5G MU-MIMO Wireless Access Operating in mm-wave Frequency Bands

    SBC: RF Pixels, Inc.            Topic: EW

    The broader impact/commercial potential of this project focuses on the development of a patented radio front-end supporting multi-user MIMO capability for the 5G mm-wave infrastructure market that would enable cost efficient, high data rate access wirelessly as opposed to cost prohibitive fiber-based data connectivity. Cellular and Wi-Fi networks are hitting a spectrum bottleneck in terms of their ...

    SBIR Phase II 2019 National Science Foundation
  6. SBIR Phase II: Virtual and Augmented Reality Enabled Personalized Manufacturing Training

    SBC: SimInsights, Inc.            Topic: EA

    The broader impact of this Small Business Innovation Research SBIR Phase II project will be achieved through investigating approaches to leverage extended reality (XR) for immersive, interactive and intelligent training in manufacturing, healthcare and higher education, to accelerate learning, increase engagement, and foster more effective use of expensive equipment. In 2017, the global training m ...

    SBIR Phase II 2019 National Science Foundation
  7. SBIR Phase II: Compact, Low-cost, Automated 3D Ultrasound System for Regular and Accessible Breast Imaging

    SBC: ISONO HEALTH, INC.            Topic: SH

    The broader/commercial impact of this SBIR Phase II project introduces a new paradigm in breast cancer screening with a cost-effective and accessible platform for personalized breast health monitoring, empowering women and their physicians with accurate and actionable data. In the US, over 300,000 women are diagnosed and 40,000 women die from breast cancer annually. Breast cancer has a 99% surviva ...

    SBIR Phase II 2019 National Science Foundation
  8. SBIR Phase II: Venous Valve Prosthesis as a Cure for Chronic Venous Insufficiency

    SBC: Innovein, Inc.            Topic: BM

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project will be to develop a medical device for valve replacement treatment of chronic insufficiency of the veins (CVI). Currently, no definitive treatment option exists to address the underlying cause of the disease, valvular reflux, which leaves millions of patients with chronic venous ulcers, skin ...

    SBIR Phase II 2019 National Science Foundation
  9. SBIR Phase II: e-CHEM: A fully-autonomous connected in-situ chemical sensor

    SBC: FLUIDION US Inc            Topic: CT

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project will be on public health, with the proposed "e-CHEM" solution enabling the monitoring of chemical water quality with high temporal resolution, providing early alerts when quality degrades. The World Health Organization has recognized water chemical safety risk management as essential for ensuring publ ...

    SBIR Phase II 2019 National Science Foundation
  10. SBIR Phase II: Hardware and Software Systems for Testing Engineered Microorganisms

    SBC: Culture Robotics, Inc            Topic: BT

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is to develop technology to bring biomanufactured products to market more rapidly. Today, biology researchers use genetic engineering to turn microorganisms into living factories: Cells that produce novel therapeutics, foods, materials, and fuels. This project will make it easier for research ...

    SBIR Phase II 2019 National Science Foundation
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