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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. IGF::OT::IGF SBIR TOPIC 379: DIGIBIOMARC: DIGITAL BIOMARKERS FOR CLINICAL IMPACT- MOONSHOT PROJECT(FAST TRACK)

    SBC: Medable Inc.            Topic: NCI

    The overall objective of this Fast Track SBIR contract project is to develop DigiBioMarCTMDigital BioMarkers for Clinical Impacta scalable and flexible cloud based platform to capture and analyze wearableimplantableor external device dataThis platform also provides an informatics tool for automated data aggregationintegrationand machine learning algorithmsIt is based on the scalable user centered ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Structure-based discovery of dopamine D1 receptor selective small molecule ligands

    SBC: CONFOMETRX, INC.            Topic: 101

    Dopamine receptors are a family of G protein-coupled receptors (GPCRs), and can be further divided into D1-like (D1 and D5) and D2-like (D2, D3 and D4) subfamilies. In this proposal, we focus on D1 receptor, which is widely expressed in brain at high levels. Modulation of D1 activity is implicated in the treatment of many psychiatric and neurological disorders, such as schizophrenia, attention def ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Rapid and Simple Paper Strip Test for the Multiplexed Detection of Gastrointestinal Pathogens at the Point-of-Need

    SBC: Godx Inc.            Topic: 950

    PROJECT SUMMARY GoDx, Inc. has been developing a prototype multiplexed paper strip device for the detection of the DNA and RNA of gastrointestinal pathogens at the point-of-need in andlt; 30 minutes with funding from the NCATS SBIR parent grant TR 001912. We have used the same platform technology we are developing in the parent grant to develop a rapid (andlt;30 minute), low-cost and instrument-fr ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Large-scale Computing Distributed Intrusion Detection System

    SBC: Physical Optics Corporation            Topic: 04a

    The facilities, centers, infrastructure, and resources of the sponsor of the proposed project are designed to be easily accessible to users over the worldwide network, while ensuring the important tasks of effective cybersecurity monitoring, situational awareness, logging, reporting, intrusion prevention, remediation, etc. Although many existing cybersecurity (detection or prevention) software too ...

    SBIR Phase I 2019 Department of Energy
  5. Energy-Efficient Reconfigurable Universal Accelerator Interconnect

    SBC: FREEDOM PHOTONICS LLC            Topic: 05a

    Recent advances in computing systems fundamentally changed the way we run our everyday lives; our healthcare, finances, scientific discoveries, and entertainment activities all heavily depend on computing infrastructures, and we are likely to increasingly depend on them in the future. However, typical high-performance-computing systems and datacenters already consume megawatts of power, and future ...

    SBIR Phase I 2019 Department of Energy
  6. Oxygen Isotope and Carbon Dioxide Analyzer for Measurements of Respiratory Quotients and Mechanisms in Soil and Dissolved Gases

    SBC: NIKIRA LABS INC.            Topic: 24b

    DOE manages one of the largest groundwater and soil remediation efforts in the world and is responsible for the remediation of 6.5 trillion liters of contaminated ground water and 40 million cubic meters of contaminated soil generated at over 7000 discrete sites. These efforts often involve bioremediation, in which substances are injected into the subsurface to enhance microbial decomposition, and ...

    SBIR Phase I 2019 Department of Energy
  7. CryoSheet Jet¿: A Novel Vitrification Method for Biological Specimens

    SBC: NEPTUNE FLUID FLOW SYSTEMS, LLC.            Topic: 26a

    With advances in detector technology and software algorithms, single-particle cryo- electron microscopy (cryo-EM) has taken the structural biology field by storm in the past five years. As the demand for three-dimensional reconstruction of biomacromolecules grows exponentially in both the academic and industrial sectors, technology features such as high throughput, high resolution, and automation ...

    SBIR Phase I 2019 Department of Energy
  8. Transparent, High-Resolution, Real-time X-ray Beam Imaging System

    SBC: Physical Optics Corporation            Topic: 13a

    Fundamental research is ongoing to support missions in energy, environment, and national security and, particularly, to provide foundations for new energy technologies and materials and chemical characterization through X-rays. Diffraction-limited synchrotron light sources will increase the coherent X-ray flux (up to a few orders of magnitude) and brilliance. Many beamlines can dynamically change ...

    SBIR Phase I 2019 Department of Energy
  9. Low Temperature Thermionic Electron Source With Narrow Energy Spread

    SBC: SPARK THERMIONICS, INC.            Topic: 15c

    A major challenge in the field of electron microscopy is to reach energy resolution as low as 1 meV, which would improve the performance of currently used technologies and facilitate the development of novel techniques. The main roadblock limiting these developments are the currently available electron sources, which can only achieve resolution of 10 meV, an achievement that is already linked to m ...

    SBIR Phase I 2019 Department of Energy
  10. MULTI-MODED MULTI-FREQUENCY FAST SINGLE BUNCH BEAM DIAGNOSTIC INSTRUMENT

    SBC: TIBARAY, INC.            Topic: 09a

    Statement of Problem: Although beam control is critical to the optimal operation of accelerators, both for the large systems that exists in national and international laboratories and for industrial and medical accelerators, it is compromised by the high costs of diagnostic detectors and the need for information from multiple detectors to generate a complete picture of what is happening to the bea ...

    SBIR Phase I 2019 Department of Energy
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