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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. EMERGENCY VENTILATORY SUPPORT DEVICES BASED ON H202

    SBC: Abel Company            Topic: N/A

    THERE IS A CLEAR NEED FOR AN EMERGENCY OXYGEN DELIVERY SYSTEM THAT COMBINES RELIABILITY, LONG-TERM STORAGE CAPABILITY, VARIABLE AND CONTROLLABLE FLOW RATE, SMALL SIZE,SAFETY, AND SIMPLICITY OF USE. OF THE AVAILABLE OXYGEN STORAGE MEDIA, CHEMICAL SYSTEMS OFFER A REASONABLE LIKELI- HOOD OF ACHIEVING SUCH A SYSTEM. THIS PROJECT WILL INVESTIGATE THE FEASIBILITY OF USING LOW-COST HYDROGEN PEROXIDE AS T ...

    SBIR Phase II 1987 Department of Health and Human Services
  2. OXYGEN GENERATOR FOR AMBULATORY COPD PATIENTS

    SBC: Abel Company            Topic: N/A

    THE SPECIFIC GOAL OF THIS RESEARCH IS THE DEVELOPMENT OF A PORTABLE OXYGEN SOURCE SUITABLE FOR USE IN PROVIDING SUPPLE-MENTAL OXYGEN TO INDIVIDUALS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) RESULTING FROM CHRONIC BRONCHIOLI- TIS, PULMONARY EMPHYSEMA, ASTHMA, OR CHRONIC BRONCHITIS. THE CONCEPT IS BASED ON THE USE OF A COMMON, LOW-COST, HOUSEHOLD CHEMICAL THAT GENERATES OXYGEN WHEN WATER PLU ...

    SBIR Phase II 1987 Department of Health and Human Services
  3. DEVELOPMENT AND TESTING OF LAMINAR FLOW ISOLATORS FOR RODENT COLONIES

    SBC: Abel Company            Topic: N/A

    THE SPECIFIC AIM OF THIS STUDY IS TO DESIGN AND EVALUATE THEUSE OF HEPA-FILTERED, LAMINAR FLOW ISOLATION SYSTEMS AS SUBSTITUTES FOR PRESENT BARRIER SYSTEMS IN GERM-FREE AND GNOTOBIOTIC RESEARCH USING RODENTS AND OTHER SMALL ANIMALS.

    SBIR Phase I 1987 Department of Health and Human Services
  4. STIMULUS PAIRS IN 3D AUDITORY BRAINSTEM RESPONSE

    SBC: ABRATECH CORPORATION            Topic: N/A

    THE GOAL OF THIS RESEARCH IS TO DETERMINE THE FEASIBILITY OF COMBINING THREE-CHANNEL RECORDING OF THE AUDITORY BRAINSTEM RESPONSE (ABR) WITH A STIMULUS-PAIRS TECHNIQUE SO AS TO MEASURE THE DECREMENT IN RESPONSE THAT OCCURS IN THE RELATIVE REFRACTORY PERIOD (RRP). THIS METHOD WILL PERMIT DETECTION OF ANY ABNORMALITIES THAT AFFECT THE RRP, AS THE PARAMETERS CAN BE ADJUSTED SO THAT THERE IS DECREMENT ...

    SBIR Phase I 1987 Department of Health and Human Services
  5. MEASUREMENT OF INTERLEUKIN-2 AND INTERLEUKIN-2 RECEPTOR BY ELISA

    SBC: Advanced Allergy Res Ctrs Inc            Topic: N/A

    DURING THE PAST 20 YEARS, DIFFERENT BIOLOGICAL ACTIVITIES HAVE BEEN DESCRIBED FOR LYMPHOKINES PRODUCED BY ACTIVATED LEUKOCYTES. INTERLEUKIN-1 (IL-1) IS A FACTOR PRODUCED BY ACTIVATED MONONUCLEAR PHAGOCYTES AND IS ESSENTIAL FOR SUPPORTING BOTH T-CELL AND B-CELL RESPONSES. ACTIVATED T CELLS PRODUCE INTERLEUKIN-2 (IL-2), A FACTOR NECESSARY FOR T-CELL PROLIFERATION. THIS SOLUBLE FACTOR EXERTS ITS BIOL ...

    SBIR Phase I 1987 Department of Health and Human Services
  6. IONTOPHORETIC CATHETER RESEARCH

    SBC: Advanced Clinical Products Inc            Topic: N/A

    THE URINARY TRACT IS A MAJOR SITE OF NOSOCOMIAL INFECTIONS. THE LEADING CAUSE OF THESE INFECTIONS IS URINARY CATHETERIZATION, WHICH IN TURN IS THE MOST COMMON PREDISPOSING FACTOR FOR FATAL GRAM-NEGATIVE SEPSIS IN HOSPITALS. THE LONG-TERM OBJECTIVE OF IONTOPHORETIC CATHETER RESEARCH IS TO DEVELOP A DEVICE TO PREVENT CATHETER-RELATED URINARY TRACT INFECTIONS. THE ULTIMATE CONFIGURATION ENVISIONED CO ...

    SBIR Phase I 1987 Department of Health and Human Services
  7. ASSAY FOR PREDICTING METHOTREXATE SENSITIVITY IN HUMAN BREAST CANCER

    SBC: Aeron Biotechnology, Inc.            Topic: N/A

    THE LONG-RANGE GOAL OF THIS PROPOSAL IS TO DEVELOP AN IN VITRO TEST TO IMPROVE SELECTION OF THERAPIES FOR INDIVD- UAL BREAST CANCER PATIENTS BY PREDICTING RESPONSE TO METHO- TREXATE. EXISTING ASSAYS FOR BREAST CANCER CELLS CANNOT DE-TERMINE METHOTREXATE SENSITIVITY BECAUSE OF REQUIREMENTS FORFOR FEEDER LAYERS AND MEDIUM COMPONENTS THAT CAN RESCUE SEN-SITIVE CELLS. THIS PROPOSA WILL,THEREFORE, EVAL ...

    SBIR Phase II 1987 Department of Health and Human Services
  8. CARRAGEENAN-STABILIZED COLLOIDAL GOLD BIOSENSOR ELECTRODES

    SBC: ALDERON BIOSCIENCES, INC.            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  9. AN IMAGE PREPARATION AND PRESENTATION SYSTEM FOR PSYCHOBIOLOGY

    SBC: American Innovision, Inc.            Topic: N/A

    NEWLY AVAILABLE TECHNOLOGY MAKES IT POSSIBLE TO CONSTRUCT VIDEO-BASED DEVICES FOR PREPARING AND PRESENTING VIDEO IMAGES THAT INCORPORATE FUNCTIONS OF MANY DIFFERENT TYPES OFIMAGE PRESENTATION SYSTEMS CURRENTLY IN USE IN LEARNING, BEHAVIOR, AND VISION RESEARCH. THE IMAGE EDITOR WOULD INCLUDE THE CAPACITY TO TAKE SELECTED PORTIONS OF VIDEO IMAGES AND REARRANGE THEM AS DESIRED TO CREATE A STIMULUS IM ...

    SBIR Phase II 1987 Department of Health and Human Services
  10. FALL-EVENT RECORDING SYSTEM

    SBC: ANCO ENGINEERS, INC.            Topic: N/A

    TO FURTHER BIOMEDICAL AND CLINICAL RESEARCH INTO THE AGING PROCESS, A VIDEO-RECORDING SYSTEM PERMITTING THE GENERATION OF A VIDEO DATA LIBRARY OF FALL EVENTS IS NEEDED. THIS PROPOSAL DELINEATES THE FUNCTIONAL REQUIREMENTS OF A VIDEO-RECORDING SYSTEM THAT WOULD AUTOMATICALLY RECORD FALL EVENTS. ITS UNIQUE FEATURES WILL INCLUDE THE ABILITY TO RECORD THE ENTIRE EVENT, INCLUDING THE CIRCUMSTANCES AND ...

    SBIR Phase I 1987 Department of Health and Human Services

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