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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. N/A

    SBC: ABRATECH CORPORATION            Topic: N/A

    N/A

    SBIR Phase I 2003 Department of Health and Human Services
  2. N/A

    SBC: ABRATECH CORPORATION            Topic: N/A

    N/A

    SBIR Phase II 2003 Department of Health and Human Services
  3. ABR train-block detection of small acoustic neuromas

    SBC: ABRATECH CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The evoked response called the ABR (Auditory Brainstem Response) is affected by nerve compression by acoustic neuromas, but is not presently sensitive enough to detect small tumors. If the ABR could be used to detect tumors, it would reduce overall medical costs and also provide a means to judge rate of tumor progression. This project proposes to improve the s ...

    SBIR Phase I 2003 Department of Health and Human Services
  4. In vivo transcription factor DNA binding analysis

    SBC: ACTIVE MOTIF, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Currently, there exist a number of methods for the study of transcription factors and gene-promoter activity. These include reporter gene assays, gel shift assays, and expression-profiling methods such as microarray analysis and SAGE. These methods are well established and have been used to generate a wealth of information. Accordingly, there are many commercia ...

    SBIR Phase I 2003 Department of Health and Human Services
  5. Novel conformation-based nuclear receptor activity assay

    SBC: ACTIVE MOTIF, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this proposal is the development of novel methods for the study of the Class II Nuclear Receptors Thyroid hormone receptor (TR), Retinoic Acid Receptor (RAR), and Vitamin D3 Receptor (VDR). Like other members of the nuclear receptor superfamily, these transcription factors directly activate or repress target genes by binding to DNA response ele ...

    SBIR Phase I 2003 Department of Health and Human Services
  6. Activity-based Proteomics for Toxicological Analysis

    SBC: ACTIVX BIOSCIENCES            Topic: N/A

    DESCRIPTION (provided by applicant): ActivX Biosciences (ActivX) will develop and validate a novel toxicoproteomics platform to correlate changes in protein activity with compound toxicology. This platform uses fluorescent chemical probes to interrogate catalytically active proteins related by super-family derived from any biological sample. Alterations in protein activity are expected to be mor ...

    SBIR Phase II 2003 Department of Health and Human Services
  7. Binaural Assessment Instrument for Cochlear Implants

    SBC: ADVANCED BIONICS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The primary purpose of the proposed research is to develop, validate, implement, and norm a practical binaural assessment protocol that can be used clinically with bilateral cochlear implant patients. The protocol will be implemented in a computerized instrument to be developed in the course of the project. Binaural assessment of a cochlear implant patient will ...

    SBIR Phase I 2003 Department of Health and Human Services
  8. Biobehavioral Measurements of Alertness in Sleep Apnea

    SBC: ADVANCED BRAIN MONITORING, INC.            Topic: N/A

    DESCRIPTION (Applicant's abstract): The proposed research evaluates the efficacy of the Alertness Profiling (AP) System as a method for objectively quantifying alertness in Sleep Apnea (SA) patients. The AP simultaneously measures electroencephalographic (EEG) indices and performance during vigilance, attention and memory tests. Combining EED and neurobehavioral assessment in a one-hour session, t ...

    SBIR Phase II 2003 Department of Health and Human Services
  9. Automated Detection of Sleep Disordered Breathing

    SBC: ADVANCED BRAIN MONITORING, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The Apnea Risk Evaluation System (ARES) is an inexpensive, in-home method assessing for sleep-disordered breathing. ARES utilizes expert software to integrate analysis of nocturnal oxygen saturation, pulse rate, snoring sounds, head position/movement recordings acquired with a self-applied, portable single-site (forehead) device with analysis of responses to a ...

    SBIR Phase I 2003 Department of Health and Human Services
  10. N/A

    SBC: ADVANCED DIGITAL SYSTEMS, INC.            Topic: N/A

    N/A

    SBIR Phase I 2003 Department of Health and Human Services

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