Award Data

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project consists of (1) preventing server-level data breaches; and (2) increasing adoption of cloud computing; especially in sectors that inherently deal with sensitive data and are subject to regulation. This includes the healthcare and finance industries as well as government agencies. Data breaches ...

Every year, the global wind industry loses an estimated $100M or more to damage caused by lightning.A new blade coating will reduce the damage to wind turbine blades caused by lightning by promoting the formation of ionization channels over the surface of the turbine blades, providing a safe external path for lightning energy to reach ground and preventing damaging blade punctures.The coating cons ...

With development of shale gas fracking, large amounts of methane and ethane have now become available at low cost. With this low cost ethane it is desirable to convert low cost ethane to high value ethylene. Oxidative dehydrogenation (ODH) for low cost conversion of ethane to ethylene is a potentially attractive route. ODH is an exothermic process for converting ethane to ethylene. By contrast pro ...

Next generation, 3D-TPS heat shields based on 3D weaving technology offer potential for increased mass efficiency relative to legacy solutions.nbsp; However, width, thickness and unit cell size combinations of 3D-TPS designs being considered for future missions are pushing the limits of current 3D weaving looms and driving the need for new or significantly modified set-ups.nbsp; With this SBIR Pha ...

PROJECT SUMMARY Resective neurosurgery is essential for treating a range of neurologic conditions such as epilepsy and brain tumorsFor some patientswhose lesion is close to cortical language areaspostoperative expressive or receptive language deficit is a major and feared postoperative complicationMuch effort is devoted to identifying the cortical language regionsand relating such localization to ...

ABSTRACTThe threat of radiological and nuclear accidents or attacks demands for effective radiation medical countermeasuresMCMable to mitigate and treat the effects of exposure to ionizing radiationsHematopoietic acute radiation syndromeHRASand cutaneous radiation syndromeCRSpose severelife threatening risks to exposed individualsCurrently no effective radio mitigatorto be administered after radia ...

Mucormycosis is one of the deadliest of the invasive fungal infections. Mucormycosis occurs most often in patients with hematological malignancies undergoing chemotherapy, patients who have received hematopoietic stem cell transplants or patients with diabetes mellitus. Improved diagnosis is the most frequently noted unmet need for management of the mucormycosis patient. Delays in treatment increa ...

1 PROJECT SUMMARY2 This application for a Phase II SBIR award extends the successful completion of Phase I and represents a 3 collaboration between Clinitech, LLC and McLean Hospital/Harvard Medical School to continue the4 development of a wearable biosensor for detecting alcohol in the interstitial fluid of humans. Excessive use of5 alcohol accounts for much of the public health burden related to ...

Major depressive disorder is a debilitating mood disorder that affects ~7% of US adults in their lifetime, costing the U.S. economy more than $200 billion a year. Drugs that increase monoaminergic signaling are the mainstay of depression therapy, but have a delayed onset of action and are only effective in about 50% of affected patients. Aberrant brain-derived neurotrophic factor (BDNF) signaling ...

Tinea capitis (ringworm of the scalp) and onychomycosis (fungal nail infection) are infections that are most often caused by dermatophytes of the fungal genera Trichophyton and Microsporum. These two infections affect approximately 14 million people in the U.S. each year. Dermatophyte infections of the hair and nails are treated with oral antifungals for up to 12 weeks. Due to potential adverse ef ...