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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. CARRAGEENAN-STABILIZED COLLOIDAL GOLD BIOSENSOR ELECTRODES

    SBC: ALDERON BIOSCIENCES, INC.            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  2. PORTABLE SYSTEM FOR CONTROL OF ANTICOAGULANT THERAPY

    SBC: Biotherm, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  3. ELCA ASSAY OF CLINICALLY IMPORTANT CLOTTING FACTORS

    SBC: Elcatech, Inc.            Topic: N/A

    A NEW TECHNIQUE HAS BEEN DEVELOPED TO ASSAY CLOTTING FACTORS: SOLID-PHASE FIBRINOGEN AND LABELLED FIBRINOGEN TOGETHER ARE USED AS A SUBSTRATE TO DETECT THROMBIN GENERA- TED FROM THE CLOTTING CASCADE. WHEN THROMBIN CLEAVES BOTH FORMS OF FIBRINOGEN TO FIBRIN, THE LABELLED FIBRIN IN SOLU- TION ASSOCIATES WITH THE SOLID PHASE. THIS TECHNIQUE, WHICHHAS BEEN NAMED "ENZYME-LINKED COAGULATION ASSAY" OR EL ...

    SBIR Phase II 1987 Department of Health and Human Services
  4. HORIZONTAL LIGHT PATH7VISION ENHANCING SYSTEM

    SBC: Ocutech, Inc.            Topic: N/A

    A NOVEL HORIZONTAL LIGHT PATHVISION ENHANCING SYSTEM (HLP-VES) CAPABLE OF 2X TO 6X MAGNIFICATION AND MOUNTED ACROSS THE FACIAL PLANE WILL BE STUDIED 1. SURVEY OF CURRENT USAGE OF TELESCOPIC VISION AIDS; 2. OPTIMIZATION OF OPTICAL DESIGN IN DESIRABLE MAGNIFICATION POWERS INCORPORATING THE HLP-VES PRINCIPLE; 3. PRELIMINARY DESIGNS OF OPTICAL CHASSIS AND MOUNTING; 4. IDENTIFICATION OF COMPONENT SOURC ...

    SBIR Phase II 1987 Department of Health and Human Services
  5. TEACHING DIABETES SELF-CONTROL WITH COMPUTER ASSISTANCE

    SBC: Pharmacy Consultation Services            Topic: N/A

    THE LONG-TERM RESEARCH OBJECTIVE IS TO MAKE COMMERCIALLY AVAILABLE A MICROCOMPUTER-BASED SYSTEM TO FACILITATE PATIENT SELF-CONTROL OF INSULIN DEPENDENT DIABETES MELLITUS. THIS COMPREHENSIVE ""DIABETES IN SELF-CONTROL (DISC) SYSTEM'' IS COMPOSED OF: 1.AN INSTRUCTIONAL AND REINFORCEMENT COMPONENT FOR COMPUTER ASSISTED HOME BLOOD GLUCOSE MONITORING; 2.A COMPONENT WHICH PROVIDES COMPUTER ASSISTED INST ...

    SBIR Phase II 1987 Department of Health and Human Services
  6. PURIFICATION OF MELANOMA 250 KD TUMOR-ASSOCIATED ANTIGEN

    SBC: Piedmont Research Company            Topic: N/A

    THE GOAL OF THIS PROJECT IS TO IMPROVE THE EXISTING PURIFICATION PROCEDURE, DEVELOPED BY PIEDMONT RESEARCH COMPANY, FOR THE 250 KD MELANOMA TUMOR-ASSOCIATED ANTIGEN (TAA) TO ALLOW PRODUCTION OF ADEQUATE QUANTITIES OF PURIFIEDTAA FOR CLINICAL EVALUATION. PURIFIED TAA MAY PROVE AN EFFICIENT AGENT FOR IMMUNOTHERAPY AND FOR SPECIFIC IN VITRO ACTIVATION OF PATIENT T CELLS FOR SUBSEQUENT THERAPY. BOTH T ...

    SBIR Phase I 1987 Department of Health and Human Services
  7. SOFTWARE FOR ANALYSIS OF INCOMPLETE LONGITUDINAL DATA

    SBC: Rho, Inc.            Topic: N/A

    MEDICAL RESEARCH FREQUENTLY INVOLVES LONGITUDINAL AND/OR MULTIVARIATE MEASUREMENTS; WHEN THE RESEARCH INVOLVES HUMANSOR LABORATORY ANIMALS, THE DATA ARE OFTEN INCOMPLETE OR INVOLVE TIME-DEPENDENT COVARIATES, PROBLEMS THAT TRADITIONALSTATISTICAL TECHNIQUES AND SOFTWARE CANNOT HANDLE PROPERLY. MANY IMPORTANT ADVANCES HAVE BEEN MADE IN STATISTICAL METHODS FOR INCOMPLETE LONGITUDINAL/MULTIVARIATEDATA ...

    SBIR Phase I 1987 Department of Health and Human Services
  8. PROTEIN KINASE C THERAPEUTIC DEVELOPMENTAL TOOLS

    SBC: Sphinx Pharmaceuticals            Topic: N/A

    THE LONG-TERM GOALS OF THIS RESEARCH ARE TO CONTRIBUTE TO ANUNDERSTANDING OF THE ROLE OF PROTEIN KINASE C IN NEOPLASTIC TRANSFORMATION AND CELLULAR REGULATION BY SIGNAL TRANSDUCTION PROCESSES. PROTEIN KINASE C FUNCTIONS TO TRANSDUCE SN-1,2-DIACYLGLYCEROL SECOND MESSENGERS, PRODUCED IN RESPONSE TO GROWTH FACTORS, NEUROTRANSMITTERS, HORMONES, AND SOME ONCOGENE PRODUCTS, AND IT IS THE RECEPTOR OF TUM ...

    SBIR Phase I 1987 Department of Health and Human Services
  9. AN INTERACTIVE BIOMEDICAL IMAGE PROCESSOR/ANALYZER

    SBC: American Innovision, Inc.            Topic: N/A

    CURRENT MORPHOMETRY AND IMAGE ANALYSIS SYSTEMS CAN BE BROADLY DIVIDED INTO THOSE WHICH DISPLAY AN IMAGE AND REQUIRE THE USER TO TRACE THE POINTS OR LINES CONSIDERED SIGNIFICANT, AND THOSE WHICH APPLY COMPLEX ALGORITHMS TO LOCATE SIGNIFICANT OBJECTS AUTONOMOUSLY. WE SEE A NEED FOR AN INTERMEDIATE TYPE OF SYSTEM IN WHICH THE USER COULD RAPIDLY INDICATE THE APPROXIMATE LOCATION OF SIGNIFICANT OBJECTS ...

    SBIR Phase II 1985 Department of Health and Human Services
  10. THE NONINVASIVE ULTRASOUND IMAGING OF THE ADULT BRAIN THROUGH THE INTACT SKULL HAS HAD LIMITED SUCCESS DUE TO THE TRANSMISSION DISTORTION OF THE SKULL.

    SBC: Autrec            Topic: N/A

    THE NONINVASIVE ULTRASOUND IMAGING OF THE ADULT BRAIN THROUGH THE INTACT SKULL HAS HAD LIMITED SUCCESS DUE TO THE TRANSMISSION DISTORTION OF THE SKULL. THE FEASIBILITY OF MEASURING SCALP AND SKULL THICKNESS BY ECHO RANGING AND INTERFERENCE TECHNIQUES TO GENERATE A MODEL TO COMPENSATE FOR DISTORTION IS PROPOSED. ONCE THE THREE-DIMENSIONAL MODEL OF THE SKULL IS OBTAINED, RAY TRACING TECHNIQUES ARE U ...

    SBIR Phase I 1985 Department of Health and Human Services

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