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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Development of a Prophylactic Onchocerciasis Vaccine
SBC: PAI LIFE SCIENCES INC Topic: NIAIDHumanriver blindnessis caused by a filarial parasite and is a serious neglected tropical disease contributing to blindnessskin diseaseand chronic disability in the developing worldEstimates from the Global Burden of Disease Studyindicate thatmillion cases of onchocerciasisleading tomillion cases of vision impairmentoccur worldwide every yearThe goal of this project is to develop a safe and effecti ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Person-Centered Planning ToolKit: Development of an Application to Improve Workforce Participation for Individuals with Cognitive Disabilities Through Team Collaboration and Employment Discovery
SBC: ASSISTECH SYSTEMS LLC Topic: naThis project evaluates the usability and feasibility of a Person-Centered Planning Toolkit to address the need for increased opportunities for competitive integrated employment for individuals with cognitive disabilities. The Toolkit enhances implementation of person-centered planning (PCP), often limited by lack of follow-through on action items, and a lack of tools to match career preferences to ...
SBIR Phase II 2019 Department of Health and Human ServicesAdministration for Community Living -
Clinical Evaluation of Photobiomodulation (PBM) in dry AMD Patients
SBC: LUMITHERA INC Topic: NEIAs the population continues to age, degenerative ocular diseases become increasingly common and create a tremendous burden on the health care system. Age-related macular degeneration (AMD) represents a significant problem with 10-11 million patients at risk to progress to severe vision loss in the U.S. alone and the prevalence of AMD is expected to double by 2020. The dry and wet forms of the dise ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Silicon Photonic Blood Typing
SBC: SiDx, Inc. Topic: NHLBISUMMARY Millions of blood samples are tested annually to establish blood type compatibility between blood donors and transfusion recipients. However, current testing methods are encumbered by the need for large blood samples, transportation to centralized laboratories, time to centrifuge and perform testing, specialized reagents, and technical training needs, placing a costly burden on the medical ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Clinical Evaluation of an Innovative PSMA-targeted Radiotherapy, CTT1403, in Prostate Cancer
SBC: Cancer Targeted Technology LLC Topic: 102PROJECT ABSTRACT Prostate-Specific Membrane Antigen (PSMA) is an ideal tumor biomarker as it is expressed on andgt;90% of all prostate cancers and expression increases as the cancer progresses. Cancer Targeted Technology (CTT) has developed a unique phosphoramidate-based scaffold that binds irreversibly to PSMA leading to andgt; 90% rapid internalization and selective accumulation in tumor cells. ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Product and Regulatory Development of a Needle-Free Hemodialysis Access Port
SBC: HEALIONICS CORPORATION Topic: NHLBIProduct and Regulatory Development of a Needle-Free Hemodialysis Access Port PROJECT SUMMARY Objective: The overall objective of this SBIR Phase IIB Bridge Award project is to advance a new Needle-FreeHemodialysis Access Port to the stage of IDE approval for a subsequent first in Human study. Significance: For the nearly 500,000 End Stage Renal Disease (ESRD) kidney failure patients in the US on h ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
HLS- A Phase 1 Open-Label Dose-Escalation with Expansion Study of SX-682 in MDS Patients
SBC: Syntrix Biosystems, Inc. Topic: NHLBIThis SBIR Fast-Track proposal meets the objectives of NHLBI Small Business Topic of Special Interest for Fiscal Year 2017 Code HLS17-04. Myelodysplastic syndromes (MDS) are genetically and morphologically diverse hematopoietic neoplasms that arise from a small pool of mutant clones within hematopoietic stem and progenitor compartments. Only three drugs have received regulatory approval specificall ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
JOC-x: Chemotherapy conjugates that open tumor tight junctions to treat cancer
SBC: PAI LIFE SCIENCES INC Topic: 102PROJECT SUMMARY A central mechanism of tumor drug resistance is the maintenance of tight junctions between malignant cells preventing penetration of molecules into the tumor microenvironment. We have generated junction openers (“JO”) that are small proteins that bind to desmoglein 2 (DSG2), a junction protein that is overexpressed in many cancers. Intravenous injection of JO increases tumor pe ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Development of a Universal Assay for Minimal Residual Disease in Acute Myeloid Leukemia using Duplex Sequencing
SBC: TWINSTRAND BIOSCIENCES INC Topic: 102Acute myeloid leukemia (AML) is a morbid condition, with over 20,000 new cases and 10,000 deaths annually in the U.S. While the majority of patients achieve remission, most harbor minimal amounts of residual disease (MRD) that will ultimately lead to relapse. The ability to detect MRD is important as its presence is associated with increased risk of relapse and death, and there is considerable int ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Rapid Test to Assist Therapy in Neonatal Sepsis and Necrotizing Enterocolitis
SBC: PROTHERA BIOLOGICS, INC. Topic: RThe primary goal of this proposed research is to develop a rapid point-of-care test that assesses the risk of neonatal sepsis (NS) and/or necrotizing enterocolitis (NEC) in infants based on Inter-alpha inhibitor proteins (IAIP) levels in blood. The test is expected to be simple, user-friendly, portable and suitable for use in the NICU. NS and NEC are associated with high mortality and morbidity, i ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health