Award Data

A seminal report by MIT estimated that Enhanced Geothermal Systems (EGS) could provide 100 GW of cost competitive base-load capacity by 2050. Successful integration of this renewable power source and the offsetting of fossil fuels (mainly coal) could reduce 401 million metric tons of carbon dioxide and decrease the US total CO2 emissions by 6.1%. The development of this geothermal resources presen ...

Cyber hacking of critical infrastructure is a concern for our national security, especially in the power/electric utility sector where utilities loose $13.2M per attack. Given the vulnerabilities within the value-chain of electric delivery, the distribution network is an enormous blind-spot and highly susceptible to cyber intrusion. This project looks to address this issue, as sought by the DoE, b ...

There is a worldwide, nearly insatiable demand for renewable energy and a dramatic shift away from central power grids to smaller, more secure, robust and reliable grids powered by renewable energy. ORPC estimates the total addressable global market for marine hydrokinetics is 433 gigawatts (GW), and ORPC has taken a leadership position in the early adopter, high cost islanded community market in ...

Every year, the global wind industry loses an estimated $100M or more to damage caused by lightning.A new blade coating will reduce the damage to wind turbine blades caused by lightning by promoting the formation of ionization channels over the surface of the turbine blades, providing a safe external path for lightning energy to reach ground and preventing damaging blade punctures.The coating cons ...

With development of shale gas fracking, large amounts of methane and ethane have now become available at low cost. With this low cost ethane it is desirable to convert low cost ethane to high value ethylene. Oxidative dehydrogenation (ODH) for low cost conversion of ethane to ethylene is a potentially attractive route. ODH is an exothermic process for converting ethane to ethylene. By contrast pro ...

! PROJECT SUMMARY The research project outlined in this SBIR submission will develop the Realize, Analyze, Engage (RAE) platform into a tool to promote sustained recovery in individuals receiving treatment for substance use disorder. In this proposal, the investigators intend to deploy the RAE system- consisting of a wearable sensor, a smartphone app, and a clinical portal- to provide individuals ...

PROJECT SUMMARY Resective neurosurgery is essential for treating a range of neurologic conditions such as epilepsy and brain tumorsFor some patientswhose lesion is close to cortical language areaspostoperative expressive or receptive language deficit is a major and feared postoperative complicationMuch effort is devoted to identifying the cortical language regionsand relating such localization to ...

Major depressive disorder is a debilitating mood disorder that affects ~7% of US adults in their lifetime, costing the U.S. economy more than $200 billion a year. Drugs that increase monoaminergic signaling are the mainstay of depression therapy, but have a delayed onset of action and are only effective in about 50% of affected patients. Aberrant brain-derived neurotrophic factor (BDNF) signaling ...

Myasthenia gravis is a severe neuromuscular disease primarily caused by complement activating autoantibodies directed towards the skeletal muscle acetylcholine receptor. Present treatments are ineffectiveand uniformly have adverse effects, which negatively impact quality of life. Despite being a rare disease, myasthenia gravis is a costly one with a hospitalization expense of half a billion dollar ...

Project Summary In this Phase I SBIR projectImproving Mobile Access for Recruiting Study Volunteers from Underrepresented Populations for Alzheimerandapos s Disease Research and Other Studieswe will develop test and finalize a prototype mobile responsive website to enable broaderfasterand more cost efficient engagement of research study participants from underrepresented and minority populationsSp ...