Award Data

ABSTRACT Asthma is prevalent in overof the pediatric populationwith most pediatric patients uncontrolled or poorly controlled in their diseaseExtensive inflammation of the airways in asthma is treated using inhaled corticosteroidsICSas a maintenance therapyHoweverthese drugs can suppress growth in childrenand fear of this outcome can lead to non adherence in pediatric patientsThis results in sever ...

PROJECT SUMMARYThis proposal will develop the High-Throughput Spheroid Screening Platform (HTSSP) to create an entirely new tool to study cell-cell interactions and microenvironmental stresses that occur in tissues and tumors. Such interactions are critical in the pharmaceutical response of cells within tissues, but current methods do not allow high throughput screening (HTS) of cellular responses ...

PROJECT SUMMARY Extended X-ray absorption fine structure (EXAFS) spectroscopy is a technique that gives element-specific structural and chemical information about molecules. An enormous advantage of EXAFS spectroscopy is that it is readily applied to many different kinds of sample, including, solutions, powders, slurries, and animal tissues. Current EXAFS instruments require bright X-ray beams fro ...

Summary Cerebral malaria (CM) is a life-threatening clinical syndrome associated with malarial infection. Annually, malaria affects more than 200 million people and claims the lives of over 440,000 people worldwide, mostly African children. As a consequence of the high incidence of CM, it is often misdiagnosed for other pathologies with similar symptoms, leading to a high false positive rate for C ...

Agilvax’s AX09 is an Immunotherapy for Triple-Negative Breast Cancer: Agilvax is developing cancer immunotherapies and vaccines with its proprietary virus-like-particle (VLP) platform technology. Agilvax’s lead product, AX09, is an immunotherapy for triple-negative breast cancer (TNBC) targeting cancer stem cells (CSC) that is designed for use in combination with existing and emerging therapie ...