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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Welding High Performance Bridge Steel with a Pulsed Energy Source

    SBC: KAI, LLC            Topic: 132FH1

    This proposal is in response to announcement DTRT57-13-R-SBIR2 in the area 13.2-FH1, Development of Innovative Welding for High Performance Bridge Steel. It is proposed to use Homopolar Generator (HPG) Welding to join the high performance bridge steel in the 3” by 30” cross sections mentioned in the announcement in under 1 second. All of the energy required to perform the weld is stored in the ...

    SBIR Phase I 2014 Department of Transportation
  2. Rapid Point-of-Care Tests for Cytomegalovirus (CMV)

    SBC: Base Pair Biotechnologies, Inc.            Topic: N/A

    The human cytomegalovirus (CMV) is one of the most common intrauterine transmitted viral agents, leading to congenital CMV infection in three to ten newborns per thousand. Depending on the preexisting status of the mother, this infection leads to more or less severe symptoms and in about 2-6% the infected children die as a consequence of the infection. Beside this, sequelae occur in a number of ...

    SBIR Phase I 2014 Department of Health and Human Services
  3. Aptamers to Detect Fungi in Formalin-Fixed Sections

    SBC: Operational Techologies Corporation            Topic: N/A

    Development of novel antifungal drugs is spurring interest in the detection of pathogenic fungi in archival formalin-fixed tissues. While in situ hybridization and PCR-based methods for fungal detection in tissues exist. formaldehyde adducts on fungal DNA complicate or invalidate such detection methods. Operational Technologies Corporation (OpTech) has been developing DNA aptamers against a broad ...

    SBIR Phase I 2014 Department of Health and Human Services
  4. Screening for Alcohol-Related Liver Disease Using Breath Signatures by DMS

    SBC: Applied Nanotech, Inc.            Topic: NIAAA

    DESCRIPTION (provided by applicant): Alcohol abuse is rampant in the U.S., estimates run as high as 1 in 20 adults, and cost tens of billions of dollars in treatment and economic loss. One especially intransigent problem has been alcohol-induced organ disease such as alcoholic hepatitis and cirrhosis. These diseases can currently be diagnosed, but this requires invasive procedures such as liver bi ...

    SBIR Phase I 2014 Department of Health and Human Services
  5. A rapid, accurate, and easy-to-use diagnostic assay for STIs

    SBC: AI BIOSCIENCES, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The aim of this application is to develop a rapid, easy-to-use, and inexpensive multi-sample diagnostic system to identify sexually transmitted infection (STI) pathogens, such as Chlamydia trachomatis (CT) and Neisseriagonorrhoeae (NG) in non-traditional healthcare settings. According to the CDC, chlamydia and gonorrhea, caused by C. trachomatis and N. gonorrho ...

    SBIR Phase I 2014 Department of Health and Human Services
  6. A Sensitive and Serotype-Specific Dengue Diagnostic Test for Low-Resource Setting

    SBC: AI BIOSCIENCES, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Dengue is transmitted mainly by the Aedes aegypti mosquitoes which inhabit the tropics, making Dengue endemic to these areas. It is caused by four genetically and serologically related viruses, termed DENV1, DENV2, DENV3, and DENV4. Dengue infection is a leading cause of illness and death in the tropics and subtropics, including Puerto Rico and the U.S. Virgin ...

    SBIR Phase I 2014 Department of Health and Human Services
  7. Enhanced Efficacy Photodynamic Disinfection

    SBC: Lynntech Inc.            Topic: NIAID

    PROJECT SUMMARY This proposal is in response to the NIAID Advanced Technology SBIR (PA-10-123) Funding Opportunity. This Phase I feasibility study is an advanced technology project with a clearly identified product that will result in a clinically relevanttopical AM treatment modality. The award period and amount requested are guided by project needs and are in compliance with the issued guideline ...

    SBIR Phase I 2014 Department of Health and Human Services
  8. Optoacoustic tomography system for image-guided cryotherapy of prostate cancer

    SBC: TOMOWAVE LABORATORIES, INC.            Topic: NCI

    Summary / Abstract The objective of this Phase-I SBIR project is to develop a novel transrectal optoacoustic-ultrasonic (OU) imaging system for guiding cryotherapy of prostate cancer via real-time monitoring of ice ball formation and temperature distribution within the area of healthy tissues adjacent to the rectal wall. The proposed system will be capable of (i) non-invasive monitoring of spatial ...

    SBIR Phase I 2014 Department of Health and Human Services
  9. Inhibiting PLEKHA7 for mutant KRAS therapy

    SBC: PHusis Therapeutics Inc            Topic: NCI

    DESCRIPTION (provided by applicant): Oncogenic KRAS is found in 25% of patient tumors across many cancer types. Despite extensive effort since its discovery over 30 years ago there is still no effective treatment for KRAS tumors. An estimated 350,000 patients in the US in 2013 will be diagnosed with mutated KRAS in their tumor, and many will die of their disease. Mutated KRAS plays a critical role ...

    SBIR Phase I 2014 Department of Health and Human Services
  10. Targeted Theranostics for Metastatic Melanoma

    SBC: RADIOMEDIX, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): The American Cancer Society reports that death rates for melanoma have been rising in the United States for the past 30 years. It is one of the more common cancers in population younger than 30, and the most common cancer in adults ages 25 to 29. One characteristic of metastatic melanoma cells that is recognized as a potential target for new therapies is their ...

    SBIR Phase I 2014 Department of Health and Human Services
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