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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Compact, low-maintenance MRI system for animal lung imaging

    SBC: ABQMR, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to develop compact magnetic resonance imaging (MRI) systems for imaging lungs as well as other soft tissue in live laboratory animals based on permanent magnets that are reasonably priced and easy to maintain. Such imagers will benefit public health by improving laboratory animal research. Unlike other soft tissues, lungs are difficult to image with ...

    STTR Phase I 2007 Department of Health and Human Services
  2. Adenosine A2A receptor antagonists for the treatment of cocaine addiction

    SBC: ADENOSINE THERAPEUTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Selective antagonists of A2A adenosine receptors (A2AR) are thought to have potential for the treatment of addictive disorders, including cocaine addiction. This proposal is a phase I STTR to investigate proprietary novel, potent, selective and bioavailable A2AR blockers for the treatment of cocaine addiction. It is collaboration between Adenosine Therapeutics, ...

    SBIR Phase I 2007 Department of Health and Human Services
  3. Small Molecule Inhibitors of C. perfringens Epsilon-Toxin

    SBC: Innovative Biologics Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this SBIR Phase I proposal is to find compounds that inhibit C. perfringens epsilon-toxin action using a novel approach for the inactivation of pore-forming toxins developed at Innovative Biologics, Inc. It is based on the blocking of the target pore with molecules having the same symmetry as the pore itself. Previously, we demonstrated that ...

    SBIR Phase I 2007 Department of Health and Human Services
  4. Non-intrusive Locomotion and Gait Stability Analysis Monitoring System for the El

    SBC: AFrame Digital, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): This proposal is for SBIR Phase I research to determine the design and feasibility of an innovative, new device for advanced locomotion analysis including: ambulation assessment and fall prevention, postural perturbation assessment and activity assessment. It is fully responsive to topic areas identified as high-priority by the NIA, specifically the Geriatrics ...

    SBIR Phase I 2007 Department of Health and Human Services
  5. Random Hand Hygiene Prompts

    SBC: AMRON CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of the proposed research is to develop and demonstrate Random Hand Hygiene Prompts (RHHP). RHHP will deliver voice messages at random times on a hospital floor, reminding listeners to perform hand hygiene. Preliminary results suggest that listeners, who include nurses, physicians, visitors and patients themselves, respond to these messages by volu ...

    SBIR Phase I 2007 Department of Health and Human Services
  6. Assessing the Functional Impact of Chronic Pain

    SBC: BARRON ASSOCIATES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of the proposed R&D program is to develop and demonstrate a new approach for objectively measuring the functional impact of pain, and changes thereto, during the course of a patient's treatment. The approach is intended to be a supplement to existing methods for assessing patient functioning, which are presently based on self-report, clinician ...

    SBIR Phase I 2007 Department of Health and Human Services
  7. Early Identification of Developmental Disorders in Infants

    SBC: BARRON ASSOCIATES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Due to improvements in obstetrical and neonatal care, and an associated decrease in perinatal mortality, as well as increased risks associated with in vitro fertilization procedures, the number of preterm (< 37 weeks postmenstrual age) very low birth weight (< 1,500 g) infants born is growing [2]. Of the approximately 50,000 infants born yearly in the United St ...

    SBIR Phase I 2007 Department of Health and Human Services
  8. An Auto-Adaptive Interface for Neuromuscular Disabilities

    SBC: BARRON ASSOCIATES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The proposed research involves the development of assistive technology that is based upon a force-feedback joystick. The Barron Associates Joystick Appliance (BAJA) is targeted at individuals with neuromuscular problem s in their arms and/or hands and will compensate for many deficiencies in the operator's own movement capabilities, including lack of strength, ...

    SBIR Phase I 2007 Department of Health and Human Services
  9. An Internet application for SMART Recovery

    SBC: BEHAVIOR THERAPY ASSOCIATES, LLP            Topic: N/A

    DESCRIPTION (provided by applicant): The goals of this proposed research project are to develop, evaluate and disseminate an Internet based (web) application called Overcoming Addictions (OA). OA will be based on the cognitive-behavioral change protocol of SMART Recovery (www.smartrecovery.org). The goal of OA is to help users learn cognitive and behavioral skills to abstain from drinking, drug us ...

    SBIR Phase I 2007 Department of Health and Human Services
  10. Development of a LH-PCR Based Diagnostic for Inflammatory Bowel Disease

    SBC: BIOSPHEREX, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Inflammatory Bowel Diseases (IBDs), namely ulcerative colitis (UC) and Crohn's disease (CD), are chronic, lifelong, relapsing illnesses, affecting close to 1 million Americans and costing approximately 2 billion dollars/year to the US healthcare system. IBDs are of unknown cause, have no cure and are increasing in incidence. We have found that the diversity of ...

    SBIR Phase I 2007 Department of Health and Human Services

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