Award Data

In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...

In a pandemic or exposure to weaponized Marburg virus the morbidity, mortality and social unrest that will ensue before vaccines orMilitary operating on foreign soil as well as to the population of the US Homeland. Practically all threat agents of biological origin (except forcertain non-proteinaceous toxins, typically produced by marine organisms and fungi) have their structure and vital function ...

Marburg virus (MARV) is a filamentous enveloped non-segmented negative sense RNA virus. This viruse is considered to be extremelydangerous with case fatality rates as high as 88-90%. Extensive efforts have gone towards effective vaccines for MARV prevention, however,none have been successfully established as licensed vaccines. Glycoprotein (GP) is the only surface protein of MARV. There are substa ...

Asthma is a major health problem facing the US, and the rest of the world's population. What is needed, both for the military as well as the civilian population, are rapid screening tests that would reduce the demand for intensive examinations. Exhaled breath monitoring is thus a new tool in the non-invasive assessment of airway inflammation which may be present before the onset of airway obstruct ...

The CDL Standard and associated channelization structure was established over 20 years ago and are not optimized for current networking technologies. As networking technologies are integrated into CDL and new sensors are deployed, the demand for CDL bandwidth is increasing. Specifically, the insertion of ATM into the CDL architecture has raised some issues concerning data integrity due to the hi ...

A B technologies proposes to conduct advanced research leading to development of an enhanced Personal Visualization Environment (PVE) that will provide visualization of fused, multi-sensor, multi-spectral, image and non-image data from external sources. Our progress shows that a lightweight, eyeglass from factor having capabilities of full and partial transmissivity or full immersion virtual view ...

System dependability is an increasingly important characteristic of mission critical computer systems. These systems must be maintained in a state of readiness to perform critical functions, and must be able to perform these functions correctly despite the presence of imperfections in system components, and in the environments in which the systems operate. Automated tools are needed to assist in ...

This Phase I research proposal is directed at demonstrating the feasibility of decontaminating nerve agents on sensitive surfaces and equipment using enzyme-containing polymers. Nerve agent hydrolyzing enzyme polymers have distinct advantages over conventional technologies for agent degradation as they are compatible with biological tissues and wound sites, highly specific for chemical agents, an ...

Alpha Informatics, Limited proposes to define a set of simulation and analysis process which will allow Theater Warfare personnel to visualize analyze and manage information flow necessary to support operations foreseen in Joint Vision 2010 and JCS concepts for Network Centric Warfare. In conjunction with the Government, we will define, develop and document a set of processes which will allow The ...

Recent developments in the world political arena have led to The need for miniaturized instrumentation for rapid characterization of micro-organisms and toxins to protect military and civilian personnel against biological weapons and to allow timely administration of prophylactics. Considerable effort is currently underway to develop polymerase chain reaction (PCR) assays with automated samp ...