Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Antisense Technology for Neural Protection and Repair

    SBC: Acorda Therapeutics, Inc.            Topic: N/A

    Spinal Cord Injury (SCI) is a devastating condition for which there is no effective treatment. The cost to society is enormous because most new cases occur in people under the age of 30 and these individuals have a near normal life expectancy. Therefore, the development of a new, effective therapy to treat SCI is imperative. We propose to use an established in vitro assay to screen antisense molec ...

    SBIR Phase I 2001 Department of Health and Human Services
  2. Tenascin-C-Fragments for Spinal Cord Regeneration

    SBC: Acorda Therapeutics, Inc.            Topic: N/A

    The goal of this project is to conduct pre-clinical tests of components of the extracellular matrix molecule tenascin-C that offer potential as therapeutics for enhancing nerve fiber regeneration. This may lead to the development of a treatment for spinal cord injury, a devastating condition for which there are no reparative treatments available. The study is based on ...

    SBIR Phase I 2001 Department of Health and Human Services
  3. Antagonists of A2B Receptors Improve Insulin Sensitivity

    SBC: ADENOSINE THERAPEUTICS, LLC            Topic: N/A

    DESCRIPTION (Scanned from the Applicant's Abstract): Blockade of A2B adenosine receptors (A2BARs) increases insulin sensitivity in insulin resistant obese Zucker rats by an effect on skeletal muscle. We have synthesized and characterized the first potent and selective antagonists of A2B receptors. The goal of this phase I SBIR proposal is to develop improved A2 ...

    SBIR Phase I 2001 Department of Health and Human Services
  4. ANTAGONIST OF A2B ADENOSINE RECEPTORS FOR ASTHMA

    SBC: ADENOSINE THERAPEUTICS, LLC            Topic: N/A

    DESCRIPTION: (Adapted from the Investigator's Abstract): Adenosine administered as an aerosol to asthmatics causes bronchoconstriction, while in non-asthmatics adenosine causes bronchodilation. This occurs because the activation of A2B adenosine receptors on sensitized mast cells triggers degranulation, releasing histamine, leukotrienes, and other allergic mediators. A2B a ...

    SBIR Phase I 2001 Department of Health and Human Services
  5. N/A

    SBC: Adherence Technologies Corp.            Topic: N/A

    The purpose of this research is to develop and test the feasibility of a novel portable computerized system that will enable nursing assistants to provide improved patient care. The system will enable nursing assistants to work more efficiently, record data more accurately, and spend more time with each patient. The system is being designed for use in assisted living facilities and nursing home ...

    SBIR Phase I 2001 Department of Health and Human Services
  6. Development of a Biochip Device for In Vitro Toxicology

    SBC: AEGEN BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Accurate prediction of human responsiveness to chemical exposure is difficult, often unreliable, and invariably expensive. Thus, Aegen Biosciences is developing a microfluidic biochip device called the Animal Chip. The Animal Chip system is a biochip device containing living cells segregated into discrete yet ...

    SBIR Phase I 2001 Department of Health and Human Services
  7. N/A

    SBC: ALBANY MOLECULAR RESEARCH, INC.            Topic: N/A

    N/A

    SBIR Phase I 2001 Department of Health and Human Services
  8. Biocatalytic Synthesis of Selective D1 Agonists

    SBC: ALBANY MOLECULAR RESEARCH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): "Drug addition is a complex illness. It is characterized by compulsive, at times uncontrollable drug craving, seeking, and use that persist even in the face of extremely negative consequences." As a consequence of the extraordinary personal, social, and health care costs associated with this problem, effective drug abuse treatment ...

    SBIR Phase I 2001 Department of Health and Human Services
  9. Selective Inhibitors of Pancreatic Cholesterol Esterase

    SBC: ALBUQUERQUE AVIAN EXOTIC            Topic: N/A

    DESCRIPTION (Scanned from the Applicant's Abstract): The specific aim of this esterase (CE) inhibitor in an acute cholesterol absorption assay. Hamsters will be gavage fed 3H-labeled cholesterol with CE-inhibitor ranging from 20-200 umoles. Twenty-four hours later, hepatic and serum cholesterol absorption will be assayed. Hepatic and serum cholesterol levels will be det ...

    SBIR Phase I 2001 Department of Health and Human Services
  10. Alanyl-glutamine as Oral Rehydration & Nutrition Therapy

    SBC: ALGLUTAMINE, LLC            Topic: N/A

    DESCRIPTION (Scanned from the Applicant's Abstract): This resubmission with substantially sharpened goals and experimental design based on considerable new preliminary data now fully addresses the reviewers' questions. Building on promising preliminary data, we shall define the dose effects of alanyl-glutamine relative to glutamine, glucose, and other g ...

    SBIR Phase I 2001 Department of Health and Human Services
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