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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1 - 10 of 637 results
 
  • Record 1 TO 637

  1. Antisense Technology for Neural Protection and Repair

    SBC: Acorda Therapeutics, Inc.            Topic: N/A

    Spinal Cord Injury (SCI) is a devastating condition for which there is no effective treatment. The cost to society is enormous because most new cases occur in people under the age of 30 and these individuals have a near normal life expectancy. Therefore, the development of a new, effective therapy to treat SCI is imperative. We propose to use an established in vitro assay to screen antisense molec ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health

  2. Tenascin-C-Fragments for Spinal Cord Regeneration

    SBC: Acorda Therapeutics, Inc.            Topic: N/A

    The goal of this project is to conduct pre-clinical tests of components of the extracellular matrix molecule tenascin-C that offer potential as therapeutics for enhancing nerve fiber regeneration. This may lead to the development of a treatment for spinal cord injury, a devastating condition for which there are no reparative treatments available. The study is based on ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health

  3. Antagonists of A2B Receptors Improve Insulin Sensitivity

    SBC: ADENOSINE THERAPEUTICS, LLC            Topic: N/A

    DESCRIPTION (Scanned from the Applicant's Abstract): Blockade of A2B adenosine receptors (A2BARs) increases insulin sensitivity in insulin resistant obese Zucker rats by an effect on skeletal muscle. We have synthesized and characterized the first potent and selective antagonists of A2B receptors. The goal of this phase I SBIR proposal is to develop improved A2 ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health

  4. ANTAGONIST OF A2B ADENOSINE RECEPTORS FOR ASTHMA

    SBC: ADENOSINE THERAPEUTICS, LLC            Topic: N/A

    DESCRIPTION: (Adapted from the Investigator's Abstract): Adenosine administered as an aerosol to asthmatics causes bronchoconstriction, while in non-asthmatics adenosine causes bronchodilation. This occurs because the activation of A2B adenosine receptors on sensitized mast cells triggers degranulation, releasing histamine, leukotrienes, and other allergic mediators. A2B a ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health

  5. N/A

    SBC: Adherence Technologies Corp.            Topic: N/A

    The purpose of this research is to develop and test the feasibility of a novel portable computerized system that will enable nursing assistants to provide improved patient care. The system will enable nursing assistants to work more efficiently, record data more accurately, and spend more time with each patient. The system is being designed for use in assisted living facilities and nursing home ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health

  6. Superconducting RF Injector for High-Power Free-Electron Lasers (FEL)

    SBC: Advanced Energy Systems, Inc            Topic: N/A

    With the achievement of 1.7 kW CW IR operation and an upgrade to 10kW in progress, free-electron lasers (FEL) are now a serious option for high-power, military and commercial applications. As specifically identified in the recent

    SBIR Phase II 2001 Department of DefenseMissile Defense Agency

  7. Development of a Biochip Device for In Vitro Toxicology

    SBC: AEGEN BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Accurate prediction of human responsiveness to chemical exposure is difficult, often unreliable, and invariably expensive. Thus, Aegen Biosciences is developing a microfluidic biochip device called the Animal Chip. The Animal Chip system is a biochip device containing living cells segregated into discrete yet ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health

  8. N/A

    SBC: ALBANY MOLECULAR RESEARCH, INC.            Topic: N/A

    N/A

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health

  9. Biocatalytic Synthesis of Selective D1 Agonists

    SBC: ALBANY MOLECULAR RESEARCH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): "Drug addition is a complex illness. It is characterized by compulsive, at times uncontrollable drug craving, seeking, and use that persist even in the face of extremely negative consequences." As a consequence of the extraordinary personal, social, and health care costs associated with this problem, effective drug abuse treatment ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health

  10. Selective Inhibitors of Pancreatic Cholesterol Esterase

    SBC: ALBUQUERQUE AVIAN EXOTIC            Topic: N/A

    DESCRIPTION (Scanned from the Applicant's Abstract): The specific aim of this esterase (CE) inhibitor in an acute cholesterol absorption assay. Hamsters will be gavage fed 3H-labeled cholesterol with CE-inhibitor ranging from 20-200 umoles. Twenty-four hours later, hepatic and serum cholesterol absorption will be assayed. Hepatic and serum cholesterol levels will be det ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
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