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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Selective Inhibitors of Pancreatic Cholesterol Esterase

    SBC: ALBUQUERQUE AVIAN EXOTIC            Topic: N/A

    DESCRIPTION (Scanned from the Applicant's Abstract): The specific aim of this esterase (CE) inhibitor in an acute cholesterol absorption assay. Hamsters will be gavage fed 3H-labeled cholesterol with CE-inhibitor ranging from 20-200 umoles. Twenty-four hours later, hepatic and serum cholesterol absorption will be assayed. Hepatic and serum cholesterol levels will be det ...

    SBIR Phase I 2001 Department of Health and Human Services
  2. HIGH-PERFORMANCE STERILANT GAS FOR DIALYSIS MEMBRANES

    SBC: ENVIRONMENTAL TECHNOLOGY & EDUCATION CTR            Topic: N/A

    Virilizing congenital adrenal hyperplasia (CAH) describes a group of disorders of steroidogenesis involving the pathway from cholesterol to cortisol. Ninety-five percent of CAH results from alteration of the CYP21 gene. The salt wasting form of CAH may be fatal in the neonatal period while non-classical forms cause health problems late in life. Screening for CAH involves measuring 17-hydroxyproges ...

    SBIR Phase I 2001 Department of Health and Human Services
  3. Diagnostic Assays for Rheumatic Diseases

    SBC: JK AUTOIMMUNITY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The diagnosis of systemic lupus erythematosus is a serious public health problem. Almost 90 percent of the 2,000,000 people who have been told that they have lupus do not fulfill the diagnostic criteria to classify a person as having lupus. The laboratory test used to screen for lupus is largely ...

    STTR Phase I 2001 Department of Health and Human Services
  4. Optical Imaging Device of the Retinal Function

    SBC: Kestrel Corporation            Topic: N/A

    N/A

    SBIR Phase I 2001 Department of Health and Human Services
  5. Optical Imaging Device of the Retinal Function

    SBC: Kestrel Corporation            Topic: N/A

    N/A

    SBIR Phase II 2001 Department of Health and Human Services
  6. Donor Cornea Characterization System

    SBC: Kestrel Corporation            Topic: N/A

    DESCRIPTION (From the Applicant's Abstract): Prior to surgery the donor cornea is screened for a number of pathologies and its history is examined for contra-indicated events, including the application of refractive surgery. Current techniques, such as topological measurement, produce significant errors, resulting in rejection of viable ...

    SBIR Phase I 2001 Department of Health and Human Services
  7. MAX-ENTROPY CONTROL FOR HIGH QUALITY DIGITAL IMAGING

    SBC: Kestrel Corporation            Topic: N/A

    A low-cost, high-resolution, high-contrast color digital camera optimized for ophthalmology will be demonstrated. The maximum entropy camera will be tested for its effectiveness in meeting the image quality requirements for telemedicine and for remote screening of pre-proliferative and proliferative diabetic retinopathy. The proposed device exploits recent ...

    SBIR Phase I 2001 Department of Health and Human Services
  8. Super Resolution Spectral Fundus Imager

    SBC: Kestrel Corporation            Topic: N/A

    DESCRIPTION: Reflective images are made up of a full spectrum of color information. Differences that appear subtle to the human eye can be shown to be significant when looking at the detailed spectrum. In addition, wavelengths (such as U.V. and I.R.), which are invisible to the human eye, can be analyzed by hyperspectral imaging. ...

    SBIR Phase I 2001 Department of Health and Human Services
  9. POLICY PRO: Software To Write Policies & Procedures

    SBC: LA FAMILIA DEVELOPMENT            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to develop and evaluate an interactive CD-ROM based software product to help social service agencies produce a policy and procedures manual. The value of such a product would be to help achieve accreditation from state and federal oversight agencies and from national standard-setting organizations. S ...

    SBIR Phase I 2001 Department of Health and Human Services
  10. Novel Biosensor for Detecting Antibiotic Resistance

    SBC: Nomadics, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Antibiotic-resistant bacteria pose a substantial health risk. The available methods to detect resistant strains are expensive, time-consuming, and complicated. Nomadics will functionalize a highly sensitive amplifying fluorescent polymer (AFP) to detect extremely low concentrations of bacterial antibiotic-resistance markers. T ...

    SBIR Phase I 2001 Department of Health and Human Services

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