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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1 - 10 of 1299 results
 
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  • Record 1001 TO 1299

  1. Error-reduction in dipole-source localization models

    SBC: ABRATECH CORPORATION            Topic: N/A

    DESCRIPTION(Adapted from applicant's abstract): Multiple-channel brain evoked-response data is often recorded from the scalp, either electrically, or magnetically. The analysis of this multi-channel data commonly utilizes mathematical models, which assume that the neural generators of the evoked-respons ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health

  2. N/A

    SBC: ABRATECH CORPORATION            Topic: N/A

    N/A

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health

  3. N/A

    SBC: ABRATECH CORPORATION            Topic: N/A

    N/A

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health

  4. Molecular Standards for Hepatitis B and C Genotyping

    SBC: ACROMETRIX CORPORATION            Topic: N/A

    DESCRIPTION (Applicant's Abstract): Nucleic acid testing procedures for genotyping of viral pathogens provide results that are utilized in the diagnosis and treatment of diseases such as hepatitis and AIDS. Medical products that directly measure these genetic variants currently utilize internal standards developed by the test manufacturers. The ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health

  5. A Novel Approach to mRNA Isolation using PNAs

    SBC: ACTIVE MOTIF, INC.            Topic: N/A

    DESCRIPTION (Applicant's abstract): Peptide nucleic acids (PNAs) have a number of features that suggest they would be ideal probes for purifying mRNA. In this revised format we have demonstrated the use of phosphono PNAs (pPNAs) in an RNA isolation procedure that improves the recovery of RNAs with secondary structure at the poly A region and RNAs with short poly A tails. We ha ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health

  6. Novel 5'-end tagging of mRNA for cDNA synthesis or RACE

    SBC: ACTIVE MOTIF, INC.            Topic: N/A

    DESCRIPTION (Applicant's abstract): In this application we will discuss the rationale for the development of a novel method for chemically tagging a synthetic oligonucleotide to the 5'-end of full-length mRNAs using the cap structure (7-methyl guanosine triphosphate, m7Gppp). There are two major technical limitations in full-length cDNA library constructi ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health

  7. Isothermal Amplification for Detection of Nucleic Acids

    SBC: ACTIVE MOTIF, INC.            Topic: N/A

    In this proposal we discuss the development of a technique to amplify the signal generated when a labeled chimeric oligonucleotide hybridizes to it target sequence. Clearly there is a huge need for such a technique given the amount of variability that occurs during triditional amplification reactions, such as PCR. The chimeric oligonucleotide described in this proposal binds to it target sequ ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health

  8. Novel Protein Array Based on Binary Coded Microchips

    SBC: ACTIVE MOTIF, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall experimental approach of this proposal is targeted to design an innovative format for arraying proteins. Instead of using the common glass slide or nitrocellulose membrane to spot proteins onto, we proposed to use a silica microchip. There are two advantages of using these chips. First, each chip has its own unique id ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health

  9. Large-Area, Low-Cost, High-Resolution X-Ray Imager

    SBC: ADELPHI TECHNOLOGY INC            Topic: N/A

    The goal of this effort is to develop a large-area, low-cost medical X-ray imager with image quality comparable with state-of-the-art digital medical imagers at a significantly lower X-ray exposure to the patient. The proposed imager will combine two technologies: porous dielectric materials and microwell electronic substrates. The porous dielectric material, such as 1 mm layer of CsI at 2% of nom ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health

  10. MICROSCOPY WITH NEUTRON REFRACTIVE LENSES

    SBC: ADELPHI TECHNOLOGY INC            Topic: N/A

    DESCRIPTION (Applicant's abstract verbatim): The objective of this proposed research is to construct a prototype neutron microscope capable of imaging biological maternal. By using compound refractive lenses recently developed by Adelphi Technology microscopy is possible with imaging distances in the order of a few meters. Neutron microscopy can be a valuable comple ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
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