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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Demonstrate the Safety and Efficacy of a PRRS-RP Vaccine Candidate

    SBC: HARRISVACCINES, INC.            Topic: N/A

    Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) costs the swine industry approximately $560M annually through reproductive loss in mature females and respiratory disease in growing pigs. There is a need for new vaccines for PRRSV to battle the strain evolution and heterogeneity of this RNA virus. Currently the only available US commercial product is a Modified Live Virus (MLV) from BI- ...

    SBIR Phase II 2009 Department of Agriculture
  2. A novel magnetic resonance detector for early diagnosis of bladder cancer recurre

    SBC: ABQMR, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Bladder cancer is a common and costly disease. More than 60,000 new cases of bladder cancer are diagnosed each year in the U.S. It is the fourth most common cancer among men and the 10th among women, with a prevalence of about 500,000 in the US. Our compact NMR device will provide a rapid, accurate differential diagnosis of bladder cancer by detecting the tumor ...

    SBIR Phase I 2009 Department of Health and Human Services
  3. Development of a digital photorefractor to detect amblyogenic risk factors

    SBC: VIVAKOR, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): If left undetected and untreated, reduced vision in one eye can lead to monocular blindness in an amblyopic eye. Most vision screening is conducted on children once they have started kindergarten; this is after the critical detection period for the treatment of amblyopia. Early detection is essential for favorable prognosis. Unfortunately less than 21% of pre-k ...

    SBIR Phase I 2009 Department of Health and Human Services
  4. XRpro Discovery of Decorporation Agents

    SBC: Icagen, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Caldera Pharmaceuticals will use award-winning XRpro, a high throughput, label-free technology for producing nano-engineered radionuclide decorporation agents that are highly specific for their target radionuclide over similar elements. This proposal displays preliminary results showing specific decorporation agents for Sr(II) that do not bind Ca(II); Sr(II) is ...

    SBIR Phase I 2009 Department of Health and Human Services
  5. Health Fotonovela Strips for Spanish Language Newspapers

    SBC: MATIELLA, ANA CONSUELO AND ASSOCIATES            Topic: N/A

    DESCRIPTION (provided by applicant): Cancer research that translates into simple, easy to understand information is a challenge in mainstream USA. A lack of English language proficiency, trouble accessing health care, and socio-cultural barriers are challenges for monolingual Latinos. As of 2006, the estimated Hispanic/Latino population in the United States was 44 million (1). Almost 25 % of the L ...

    SBIR Phase I 2009 Department of Health and Human Services
  6. Liquid Cooling Cycle for Ablation Using Integrated Thermal and Imaging Feedback

    SBC: CRYOMECHANICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Interventional oncology and tumor ablation is a rapidly growing field of cancer therapy that may even be cost-effective for outpatient delivery of image-guided treatments of local tumors for potential cure or paliative management. A distinct benefit of cryotherapy over heat-based ablations is the excellent visualization of ice margins by CT, US and MRI. How ...

    SBIR Phase I 2009 Department of Health and Human Services
  7. Development of Methods and Software for Interior Tomography Applications

    SBC: INTERIORSOFT, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): In contrast to the conventional wisdom that the interior problem does not have a unique solution, in 2007 we developed and patented the interior tomography technology (exact and stable interior reconstruction from x-ray projection data associated with only lines through an internal region of interest). When applying conventional CT algorithms to such an incompl ...

    SBIR Phase I 2009 Department of Health and Human Services
  8. Novel immune-based therapy for leishmaniasis and tuberculosis

    SBC: NEWLINK GENETICS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Indolamine 2,3-deoxygenase enzymes (IDO-1 and IDO-2) play important counter-regulatory roles in the immune system. IDO-mediated tryptophan catabolism induces T cell suppression, which plays a physiological role in suppressing autoimmune and allergic diseases, as well as in facilitating maternal/fetal tolerance. IDO also plays a pathophysiological role in suppre ...

    STTR Phase I 2009 Department of Health and Human Services
  9. Free Form Fabrication of Dental Copings and Restorations.

    SBC: Robocasting Enterprises, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this project is the continued development of a solid freeform fabrication system for producing dental restorations and devices which began in Phase I. This system is based on the robocasting approach. Robocasting is a solid freeform fabrication technique that uses automated extrusion of colloidal slurries, pastes, inks, etc. to build complic ...

    SBIR Phase II 2009 Department of Health and Human Services
  10. Fast-Track:Biomagnetic In-vivo Imaging of Ovarian Cancer

    SBC: SENIOR SCIENTIFIC            Topic: N/A

    DESCRIPTION (provided by applicant): A novel method for applying nanotechnology to the early detection, localization and potential treatment of ovarian cancer has been developed. Recent measurements, using live ovarian cancer cell lines and the ovarian cancer marker CA-125, have shown that the sensitivity of this method is better than 105 cells at depths of 5 - 8 cm from the sensor. This is signi ...

    SBIR Phase II 2009 Department of Health and Human Services

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