Award Data

DESCRIPTION (provided by applicant): ACell is a tissue engineering company and its core technology is based upon a porcine derived extracellular matrix (ECM) harvested from the urinary bladder (UBM) that serves as a constructive scaffold for tissue reconstruction. Successful completion of Phase I studies showed that the UBM-ECM can be configured into a tube shaped device with mechanical and materi ...

DESCRIPTION (provided by applicant): Sudden cardiac death kills 300,000 people in the United States yearly. More than half of these deaths are caused by arrhythmias including ventricular tachycardia. Radiofrequency ablation, which successfully treats supraventricular tachycardia, is not successful at treating ventricular tachycardia because conventional RF ablation catheters cannot treat a large e ...

"Current manufacturing technology for cast titanium components cannot guarantee theabsence of hard alpha inclusions.Under the effect of fatigue, such inclusions become likely sites for structuralfailure. By performing nondestructive inspections on the manufactured parts usingphased array ultrasound, one can eliminate parts with the largest inclusions.Despite such quality control, undetected inclus ...

Electrostatic discharge control is vital for the health of any spacecraft. Exposure to charged particles in a space enviroment can lead to large charge differences across the craft, that, if no mechanism for controlled discharge is present, can destroy mission critical equipment. The preferred way of ESD control is to use conducting thermal control coatings. These coatings combine the ability to r ...

The concentration of carbon dioxide in exhaled breath is 3.8%; a concentration of 2% causes deepened breathing, and 4% causes a marked increase in respiration. These higher concentrations of CO2 also cause drowsiness and can be unsafe. Therefore, it is desirable to monitor the concentration of CO2 in exhaled breath to guarantee the safety of an astronaut in the dangerous extravehicular environment ...

DESCRIPTION (provided by applicant): Obesity is a well-established risk factor for a number of diseases, including type 2 diabetes and coronary heart disease. While weight loss is the most effective treatment of type 2 diabetes, current methods for reducing weight are typically insufficient for long-term weight loss. The mission of AdipoGenix, Inc. is to discover, develop, and license novel therap ...

"R3 Logic, Incorporated proposes to perform a comprehensive study to develop a fullsuite of computer-aided design tools for three-dimensional circuit integration. Thecompany will build on its existing tool set that enables 3-D physical layout andverification and will develop recommendations for extending these tools to permitanalyses of 3-D circuit performance, including thermal and electromagneti ...

"3D-IC proposes to develop design specifications for a 12 megapixel 1000 frame / second digital output imager. The proposed design will be based on using a monolithic substrate for the photosensor array that is engineered to achieve high quantum efficiencyand good spectral response in visible light. The company proposes to investigate adaptation of its proprietary pixel-parallel processor core arc ...

"The objective of this proposal is to create an innovative bioinformatics system for the management and analysis of microarray data. It will be a new generation of informatics system that goes well beyond any system presently available. The system will notonly allow users to track the generation of data with a flexible laboratory information management system (LIMS), but it will also allow users t ...

"A compact, reliable, efficient and inexpensive cryocooler requiring less than 1kW of power for 2W of cooling at 10Kelvin is being developed and will be demonstrated. This performance is at least twice as efficient as the best current state-of-the-art forsmall low-temperature cryocoolers. The proposed technical approach, whose feasibility has been confirmed, is to apply the advantageous features ...