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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Thermostable Savin IPV
SBC: LUNA INNOVATIONS INCORPORATED Topic: ODCDCPoliomyelitisPoliois a highly infectious disease that primarily affects young childrenCurrentlythe live attenuated oral poliomyelitis vaccineOPVis the vaccine used to prevent polio outbreaks and stop transmission of wild poliovirusesHoweversometimes OPV has the ability to revert to a form that can cause paralysis or poliomyelitiswhich will inevitably lead to new polio outbreaksIn most developed co ...
SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention -
Self Stable Corneal Tissue Storage Solutions with Antifungal Additives
SBC: LUNA INNOVATIONS INCORPORATED Topic: ODCDCThere has been a recent rise in the rate of fungal infections following corneal transplant surgeries over the last six yearsand most cases have been tied to donor to recipient transmissionWhile preliminary studies have demonstrated the efficacy and safety of adding antifungal agents to the corneal storage media to minimize the risk of infectionthe shelf life of these antifungal agents is significa ...
SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention -
Topic 375: Novel Diagnostic Imaging Modality for Monitoring Tumor Responses to a Hyperthermia Immunotherapy (Moonshot)
SBC: Imago Systems, Inc. Topic: NCIImmunotherapies have been emerging in the past decades as powerful approaches for cancer treatment. However, the immune system is complex, and therapy efficacy is substantially affected by the tumor microenvironment. For this reason, it is currently difficult to visualize tumor response and predict therapeutic efficacy. In this Contract, Imago Systems, Inc., a company with substantial experience i ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A system to detect fall occurrence and location in hospital settings
SBC: BARRON ASSOCIATES, INC. Topic: NIAFall detectionassessmentand prevention is a challenging issue across the care continuumDespite wide recognition as a considerable problemfall related injuries are still the most frequently reported adverse events in hospital inpatient settingswithof patients falling at least once during their stayAccording to the Agency for Healthcare Research and Quality reportstoof falls result in injuryIn the U ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
An integrated mobile and web-based application for problem cannabis use
SBC: Checkup and Choices LLC Topic: NIDAThe objective of this research project is to develop an integrated set of digital tools that will deliver a brief motivational interventionBMIfor young adult marijuana users across a variety of platformsWe havein four randomized clinical trialsdemonstrated the effectiveness of similar tech based interventions for problem drinkingThese interventions have been integrated into one comprehensive progr ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
BT-11: A First-in-class Oral Therapeutic for Inflammatory Bowel Disease
SBC: Biotherapeutics, Inc. Topic: NIAIDBTA First in class Oral Therapeutic for Inflammatory Bowel Disease Biotherapeutics IncBTIdevelops oral first in class therapeutics for autoimmune diseasesBTa lead compound for treating inflammatory bowel diseaseIBDbelongs to a new chemotype and targets the novel Lanthionine Synthetase C LikeLANCLpathwayBTI will file an IND for BTinmonthsSignificanceIBD afflicts overmillion Americans andmillion peo ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Powerful Solid-State Sources to Enable Advanced EPR and DNP-NMR Measurements
SBC: VIRGINIA DIODES, INC. Topic: 400VDI Project Summary AbstractThe NIH Division of Cell Biology and Biophysics supports studies of the biological macromolecules that affect the function and structure of living cellsand often play a role in diseaseWithin the realm of biophysicsone of the most important tools to study the structure and interactions of these molecules is nuclear magnetic resonanceNMRFor exampleNMR has been used to stu ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A high throughput next generation sequencing (NGS) pipeline to generate high quality recombinant therapeutic antibodies
SBC: Specifica Inc. Topic: 100Abstract Therapeutic antibodies are used to treat many different diseasesincluding cancerauto immunityinfection and atherosclerosisThey are the fastest growing class of pharmaceuticalswith annual revenues of$B inOne of the most important methods to select therapeutic antibodies is by selection from vast antibody librariesHowevergood libraries are extremely challenging to produceand commercially av ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Development of immunoassays for highly sensitive diagnostic monitoring of traumatic brain injury using novel astroglial injury-defined biomarkers
SBC: Immunarray USA, Inc. Topic: 101ABSTRACT Traumatic brain injuryTBIis an expanding public health epidemic with complex pathophysiology that is difficult to diagnose and thus treatTBI blood testing should provide simplereliablereal timeobjective diagnostic monitoring and outcome prediction across the entire severity spectrumNeurotrauma biomarkers with insight into underlying TBI processes can address these needsAt UCLADrWanner s t ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Development of a DCLK1 siRNA Nanoparticle as Targeted Therapy to Treat Pancreatic Cancer
SBC: COARE HOLDINGS INC Topic: NCIAbstractPancreatic ductal adenocarcinomaPDACis one of the most devastating human cancersIt is the fourth leading cause of cancer related deaths in the U Sannuallywith a andltyear survival rateDespite FDA approved therapeutic regimens and marked improvements in medical and surgical careno significant impact on PDAC patient survival has been achievedInsomeAmericans are expected to be diagnosedandare ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health