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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Defining Therapeutic Potential of Clonal Stem Cell Populations using Targeted Nan

    SBC: OCATA THERAPEUTICS, INC.            Topic: N/A

    Project Summary Embryonic stem cells offer considerable potential for cell replacement therapy where cells have been lost to injury or disease because of their capacity for continual self renewal and ability to differentiate into virtually any cell type or tissue. Currently, however the process by which human embryonic stem cells (hESCs) differentiate into various mature functional cell types is ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  2. iGenomeTM Software Platform Prototype for Individual Genetic Health Assessment

    SBC: 3RD MILLENNIUM, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Sufficient general clinical knowledge, DNA sequence technology and understanding of genetic mutations for over 2,600 human genes can support beginning the integration of individual genome sequence into clinical practic e for a number of medical specialties. With the 2007 deployment of novel DNA sequence technologies that permit cost-effective interrogation of ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  3. Real-Time Image and Dose Guided Radiation Therapy System

    SBC: ADVANCED RADATION THERAPY            Topic: N/A

    DESCRIPTION (provided by applicant): Real-Time Image and Dose Guided Radiation Therapy System Development and integration of a real-time image- and dose-guided radiation therapy system is long overdue. Advanced Radiation Therapy has identified an opportuni ty and designed a single system that uses a common platform for imaging the target tissue in real-time, immobilizing the tissue, delivering rad ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  4. Inhaled nisin as an emergency intervention against antibiotic sensitive or resist

    SBC: AFG BIOSOLUTIONS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The deliberate release of Bacillus anthracis spores remains an imminent threat both in terms of bioterrorism and biowarfare. Individuals who inhale these spores are at extreme risk of infection and death from anthrax. C urrent prophylaxis and therapy in the event of B. anthracis spore inhalation fall into two categories. Vaccination to protect against future ex ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  5. Add-on module for ONCAD for diagnosing infiltrating lobular carcinoma

    SBC: Alan Penn & Associates Inc            Topic: N/A

    DESCRIPTION (provided by applicant): The specific aim of this study is to develop an add-on module for the ONCAD breast MRI CAD system that will provide radiologists with additional assistance when they have suspicion of the presence of infiltrating lobula r carcinoma (ILC). The proposed research will investigate the possibility of developing, training and evaluating an ILC- specific algorithm tha ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  6. Position Sensitive Microfluidic Detector

    SBC: RADIATION MONITORING DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Microfluidic chips, fabricated from low cost polymers, are a promising, emerging technology for synthesis and study of new molecular imaging probes. These chips can contain a variety of microcircuitry and microwells and are capable of manipulating nanoliter samples of reagents and solvents. The microfluidic chips have been designed for a multitude of applicati ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  7. Continuous Phoswich Detector for Molecular Imaging

    SBC: RADIATION MONITORING DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Positron Emission Tomography (PET) imaging systems used in Nuclear Medicine can suffer from loss of spatial resolution due to parallax effects, called radial elongation. A scintillation detector that allows depth-of- in teraction (DOI) determination would be an important advance. Previous attempts were made to develop DOI scintillators for PET, but all of them ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  8. High Resolution Detectors for Single Photon Cardiac Imaging

    SBC: RADIATION MONITORING DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): High Resolution Detectors for Single Photon Cardiac Imaging Single photon emission computed tomography (SPECT) is a powerful, noninvasive medical imaging modality that mathematically reconstructs the three dimensional d istribution of a radionuclide throughout the body of a human patient or a research animal. Typically, the collected data are displayed and eval ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  9. Practical Anti-Thrombotic Catheters for Improved Patient Outcome

    SBC: RADIATION MONITORING DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Venous catheters play critical roles in the administration of chemotherapy, antibiotics, blood, blood products and total parenteral nutrition essential for the successful treatment of many chronic afflictions. Recent ad vances in catheter technology have enabled the explosive growth in oncology (vascular access ports), nephrology (hemodialysis catheters) and in ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  10. Reduced Afterglow Scintillator Films for High Speed Medical Imaging

    SBC: RADIATION MONITORING DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): While many exotic new scintillation materials are now being developed, few even come close to CsI:Tl in performance and versatility. Widely available commercially at low cost, CsI:Tl not only has superb scintillation ef ficiency, but also can readily be fabricated as large-area microcolumnar films for high-resolution imaging, making it the material of choice fo ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
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