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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Clinical Human Cell Production System for Broad Use
SBC: Aastrom Biosciences, Inc. Topic: N/ADESCRIPTION (provided by applicant): As a result of growing evidence of their therapeutic potential in cancer, infectious diseases, and tissue repair, there is an enormous increase in the research and discovery of cell-based medical treatments that require cultured cells. A large unmet need exists for a cost-effective system that will facilitate the development of clinical cell production capabil ...
SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health -
Enhanced Tumor Antigen Priming of Dendritic Cell Vaccine
SBC: Aastrom Biosciences, Inc. Topic: N/ADESCRIPTION (provided by the applicant): Dendritic cells have been shown to initiate, regulate, and direct cytolytic T-cell-mediated immune responses against tumor antigens in human patients. Recent clincal trials have demonstrated induction of clinically significant immune responses against malignant diseases using DCs primed ex vivo with autologous tumor antigens including tumor cell lysates. E ...
SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health -
Automated Perfused Culture Process for Adult Stem Cells
SBC: Aastrom Biosciences, Inc. Topic: N/ADESCRIPTION (provided by applicant): Adherent mesenchymal cell populations derived from bone marrow (BM) have the capability of differentiating into multiple cell lineages in vitro and in vivo. The potential use of these populations, referred to as marrow stromal cells (MSC), in clinical applications to treat nonhematopoietic disorders is being intensely investigated. Ex vivo expansion is being us ...
SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health -
Clinical-scale Production of Osteoprogenitor Cells
SBC: Aastrom Biosciences, Inc. Topic: N/ADESCRIPTION (provided by applicant): Due to morbidity and limited amounts of material, alternatives to autologous grafts for bone repair are desirable. Mixtures of marrow stromal cells (MSC) and carrier matrices are known to augment bone repair. Increasing the number of MSC through ex vivo expansion may significantly increase the amount and rate of new bone formation. In this proposal, the abilit ...
SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health -
Automated Large-Scale Production of Endothelial Cells
SBC: Aastrom Biosciences, Inc. Topic: N/ADESCRIPTION (provided by applicant): Treatment of ischemia by administration of bone marrow (BM)-derived endothelial progenitor cells (EPC) or ex vivo expanded EPC populations has been shown to enhance vascular regeneration in animal models and in clinical trials. For cell therapy to be practical in a clinical setting, simple, efficient, GMP compliant methods for cell production are needed. Aastro ...
SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health -
Miniature Directional Microphone for Handheld Automatic Speech Recognition in Military Environments
SBC: Adherent Technologies, Inc. Topic: N/AThe Phraselator, a handheld automatic translation device, currently uses a cardioic microphone as an input for automatic speech recognition (ASR). This microphone is highly vulnerable to performance degradation in typical noisy military environments and,thus, there is a need for an improved transducer for this application. We propose to develop a new directional microphone that is immune to extr ...
SBIR Phase I 2003 Department of DefenseDefense Advanced Research Projects Agency -
UV Rigid Inflatable Wing
SBC: Adherent Technologies, Inc. Topic: N/AAs the unmanned exploration of Mars and Venus becomes more of a focus area at NASA, inflatable, rigidizable wings will become an enabling technology. The successful development of this type of wing will also have significant military applications. The utility of unmanned aerial vehicles (UAVs) for the military has been dramatically demonstrated in the conflict in Afghanistan. Rigidization of infla ...
SBIR Phase I 2003 National Aeronautics and Space Administration -
SBIR Phase I: Fiber Impregnation using Molten Thermoplastic Polymer Spray
SBC: Adherent Technologies, Inc. Topic: N/AThis Small Business Innovation Research (SBIR) Phase I project will develop a prepreg material that, while maintaining the advantages of a powder towpreg system, will eliminate the use of high price, finely ground powders. By generating fine particles in situ using aerosol formation from molten polymers two steps will be eliminated from the manufacturing process -- powder grinding and powder sin ...
SBIR Phase I 2003 National Science Foundation -
Crested Tunnel Barriers for Fast, High Density, Nonvolatile Memory Devices
SBC: ADVANCED FUEL RESEARCH, INC. Topic: N/ACrested multi-layer tunnel barriers have been proposed, which offer a revolutionary solution to overcome density to speed trade-offs characteristic of present data storage technologies. Practical implementation of the proposed technology will involve useof thin film materials that are readily manufacturable and CMOS-compatible. A critical need exists for experimental verification of the theoreti ...
STTR Phase II 2003 Department of DefenseAir Force -
Real-Time Optical Smoke Meters
SBC: ADVANCED FUEL RESEARCH, INC. Topic: N/AThe SAE smoke number has been an important measurement for prevention of black, sooty plumes in military and commercial aviation. The current method, however, requires the use of a complex extraction system to bring engine exhaust through a filter paper,and then requires a person to remove the soot covered filter and perform a measurement in an optical reflectometer to determine the smoke number. ...
SBIR Phase I 2003 Department of DefenseAir Force