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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Fate and Fortune: A Story-Based Algebra Simulator of High Seas Trade

    SBC: MidSchool Math, LLC            Topic: edIES17R0005

    With this Phase I funding, the project team will develop and test a prototype of Fate and Fortune, a simulated learning environment aligned for grade 8 algebra. The prototype will include story-based adventure set in the era of the spice trade of the 1600s. In the multi-player game, the class of students must apply algebraic equations to advance and learn academic content. At the end of Phase I, i ...

    SBIR Phase I 2017 Department of EducationInstitute of Education Sciences
  2. A Rapid Low Cost Point of Care Diagnostic for detection of Zika virus RNA

    SBC: L2 DIAGNOSTICS, LLC            Topic: NIAID

    ABSTRACT Zika virus ZIKV has rapidly emerged and spread through South and Central America the Caribbean and Puerto Rico since its last outbreak in Micronesia in Transmitted by the mosquito Aedes sp its forecasted spread will have a major impact on the Southeast U S Most ZIKV infections remain asymptomatic or present with non specific rash and fever therefore they have been difficult ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Laboratory Bench Top EXAFS with STJ Spectrometer

    SBC: STAR CRYOELECTRONICS LLC            Topic: 100

    Project Summary Extended X ray absorption fine structure EXAFS is a technique that gives element specific structural and chemical information about molecules EXAFS currently requires bright X ray beams from specialized synchrotron light sources for most samples and so its applications are limited by access to these facilities This project will involve improved X ray detectors based on superco ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Comprehensive Eye Evaluation Algorithm CEEvA

    SBC: Visionquest Biomedical LLC            Topic: M

    Summary The objective of this project is to develop the Comprehensive Eye Evaluation Algorithm CEEvA a system to achieve blindness prevention in a cost effective way CEEvA uses fundus images and available personal medical data in the electronic medical record medical history and laboratory tests to automatically screen not only for DR but also for POAG and AMD in populations at higher risks ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Reversing Isoniazid Resistance By Isotopic Substitution

    SBC: SpinCeutica, Inc.            Topic: NIAID

    Project Summary The overall goal of this project is to develop our new stable isotope labeledversion of an existing tuberculosisTBdrugisoniazidINHfor use in treated drug resistant TBWe hypothesize that our that isotope enhanced compound can be developed into a powerful new drug against INH resistant TB and multidrug resistant TBby addressing the following specific aimsSpecific AimDetermine what ot ...

    SBIR Phase II 2017 Department of Health and Human Services
  6. Tools for Faster and Cheaper Delivery of Integrated Registries

    SBC: PROMETHEUS RESEARCH, LLC            Topic: 103

    The goal of this project is to enable fastercheaper delivery of integrated registries for mental health research centers by improving the Research Exchange DatabaseRexDBan open source integrated registry platform developed by Prometheus Research during a prior Phase I SBIR awardIntegrated research registries can provide many benefits to mental health researchers and organizationsincluding easier d ...

    SBIR Phase II 2017 Department of Health and Human Services
  7. Validation of a Diagnostic Test for Borrelia miyamotoi

    SBC: L2 DIAGNOSTICS, LLC            Topic: NIAID

    ABSTRACT Borrelia miyamotoi is a tick transmitted spirochete recently shown to cause infection and disease in the United StatesEurope and AsiaA member of the relapsing fever group of Borreliathis pathogen has been proven to cause most commonly a nonspecificflu like illness with feverfatiguemyalgiaand headacheDisease can be particularly severe and involve the central nervous system in immunocomprom ...

    STTR Phase I 2017 Department of Health and Human Services
  8. Targeting STT3A and STT3B to Block Flavivirus Replication

    SBC: New England Discovery Partners, LLC            Topic: NIAID

    AbstractMosquito borne flaviviruses cause disease worldwidewith members such as dengue virusDENVZika virusZIKVand west nile virusWNVinfecting more thanmillion individuals annuallyThe availability of small molecule antivirals that reduce flavivirus infection therefore could have an immediate and substantial impact on public health programs that seek to improve outcomes for populations infected with ...

    STTR Phase I 2017 Department of Health and Human Services
  9. A wearable tech app for CheckupandChoices

    SBC: Checkup and Choices LLC            Topic: 450

    The objective of this research project is to develop a prototype app for wearable technology that will significantly enhance the effectiveness of our web based alcohol and drug intervention Checkupandamp Choices CC We have already demonstrated the effectiveness of CCandapos s components in four randomized clinical trials CC has been commercialized and is in use by the general public This pro ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Novel extracorporeal device Amytrapper to remove beta amyloid in Alzheimer s Disease

    SBC: RECOMBINANT TECHNOLOGIES LLC            Topic: N

    Abstract Alzheimer s disease AD is the most common cause of dementia among elderly patients afflicted by neurodegenerative diseases affecting about million people worldwide and regarded as the fourth most common cause of death Significant accumulation in the brain of Amyloid A is consistently observed in AD Due to its accumulation in AD removal of the toxic A from the system is expe ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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