Award Data

DESCRIPTION (provided by applicant): ACell is a tissue engineering company and its core technology is based upon a porcine derived extracellular matrix (ECM) harvested from the urinary bladder (UBM) that serves as a constructive scaffold for tissue reconstruction. Successful completion of Phase I studies showed that the UBM-ECM can be configured into a tube shaped device with mechanical and materi ...

DESCRIPTION (provided by applicant): ACell is a tissue engineering company and its core technology is based upon a porcine derived extracellular matrix (ECM) harvested from the urinary bladder (UBM) that serves as a constructive scaffold for tissue reconstruction. Successful completion of Phase I studies showed that the UBM-ECM can be configured into a tube shaped device with mechanical and materi ...

DESCRIPTION (provided by applicant): Sudden cardiac death kills 300,000 people in the United States yearly. More than half of these deaths are caused by arrhythmias including ventricular tachycardia. Radiofrequency ablation, which successfully treats supraventricular tachycardia, is not successful at treating ventricular tachycardia because conventional RF ablation catheters cannot treat a large e ...

DESCRIPTION (provided by applicant): Obesity is a well-established risk factor for a number of diseases, including type 2 diabetes and coronary heart disease. While weight loss is the most effective treatment of type 2 diabetes, current methods for reducing weight are typically insufficient for long-term weight loss. The mission of AdipoGenix, Inc. is to discover, develop, and license novel therap ...

It is becoming more difficult to treat bacterial infections such as, tuberculosis, staphylococcus, and streptococcus due to the emergence of multiple antibiotic-resistant strains. Rational drug design may prove invaluable for developing new antibiotic agents. Advanced Microbial Solutions Corporation (AMS) developing a new class of anti-microbial agents targeted at metal ion-activated transcription ...

DESCRIPTION (provided by applicant): Conservative estimates suggest that over 2 million people annually in the U. S. alone suffer from ulcers, and the base of those so afflicted is likely to increase in view of an aging population. Mean hospital charges of patients with a primary diagnosis for pressure ulcers were about $22,000 in 1992, a significant cost that will become increasingly difficult to ...

This Small Business Innovation Research Phase II project will develop a new analytical tool for characterizing drug delivery aerosols and powders. This instrument will be based on a previously developed aerosal mass spectrometer that provides real-time size distribution and chemical composition measurements for aerosol particles. During Phase I research, a new inlet for the aerosol mass spectromet ...

This Small Business Innovation Research (SBIR) Phase II project concerns the development of an optical alloy composition sensor based on laser induced plasma spectroscopy. A key element of the sensor is the use of a microchip laser excitation source. The technology has the capability to detect industrially relevant compositions in steel alloys and possibly aluminum alloys. The Phase I results in ...

This Small Business Innovation Research (SBIR) Phase II project concerns the development of an optical alloy composition sensor based on laser induced plasma spectroscopy. A key element of the sensor is the use of a microchip laser excitation source. The technology has the capability to detect industrially relevant compositions in steel alloys and possibly aluminum alloys. The Phase I results in ...

This Small Business Innovation Research Phase II project will develop a new analytical tool for characterizing drug delivery aerosols and powders. This instrument will be based on a previously developed aerosal mass spectrometer that provides real-time size distribution and chemical composition measurements for aerosol particles. During Phase I research, a new inlet for the aerosol mass spectromet ...