Award Data

DESCRIPTION (provided by applicant): The development of new treatments for the effective reduction of renal injury associated with acute renal failure and kidney transplantation will have a great impact on health care delivery to patients with renal disease. Acute ischemic renal failure affects 5 percent of hospitalized patients and has a mortality rate approaching 50 percent. At present, dialysis ...

epsis syndrome is the 11th leading cause of death in the United States ( about 900,000 new cases per year) with a mortality of about 35 percent. The need for adjunctive therapies is urgent. In Phase I of this SBIR award we documented the anti-inflammatory effects of adenosine A2A receptor (A2AAR) agonists on isolated immune cells and have observed ramatically improved survival in mouse models of I ...

DESCRIPTION (provided by applicant): The central goal of this research is to develop a new drug to prevent spinal cord reperfusion injury secondary to aortic clamping that occurs frequently during thoracic surgery. Irreversible spinal cord injury resulting in paraplegia or paraparesis is the single most devastating complication of surgery on the thoracic and thor ...

DESCRIPTION (provided by applicant): The AccuNurse System has been successfully developed in Phase I to provide an easy-to-use "mentor" and communications tool for CNAs and nurses in skilled nursing units. Wireless and advanced speech technologies are merged into a conversational system that provides: individualized resident information, paperless documentation at the point of care, and many other ...

DESCRIPTION (provided by applicant): The overall goal of the ADEPT project is to enhance the independence, autonomy, safety, and performance of patients with dementia in conducting activities of daily living (ADL). The overall objective of ADEPT development is to enhance patient care in Special Care Units (SCUs) through the further development and testing of a computerized, self-directed, traini ...

DESCRIPTION (provided by applicant): Research done prior to and including Phase I has led to publications and subsequent data that has proven the feasibility of utilizing a self-contained device as the standard of care in removing stagnated blood and generation of blood flow within congested skin flaps to promote survival. Completion of Phase I was the development of the AspiraideTM, a device that ...

DESCRIPTION (provided by applicant): The Phase II program has two key aspects: Coulter Associates will build on its successful SBIR Phase I wristwatch device to develop an innovative and even more highly miniaturized tactile device specifically for infants. This device will provide vibrotactile stimulation on the infant's forearm to create an awareness of their acoustic and speech environment. Th ...

DESCRIPTION (provided by applicant): Arsenic contamination of drinking water poses significant health risks to millions of people worldwide. Current technologies used to clean arsenic-contaminated water have significant drawbacks, such as high cost and generation of large volumes of toxic waste. Edenspace Systems Corporation proposes to create the basis for a cost-effective phytofiltration techno ...

Half of diabetic patients do not visit an ophthalmologist as recommended, resulting in frequent and unnecessary vision loss. The NEI has set as an Healthy People 2010 objective to increase the screening rate for diabetic retinopathy. EyeTel-lmaging and the Wilmer Eye Institute are developing technology to screen diabetic patients during their visits to their primary care physician (PCP). The DigiS ...

"The magnetic field distribution in a current carrying plasma, such as Z-pinch, can be used to infer the currents flowing in the pinch and to study physical process such as the Rayleigh-Taylor (R-T) instability during the implosion phase. The currentcommutation process is particularly difficult to measure in nested array loads and in concentric magnetic flux compression experiments. Faraday rotati ...