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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Clinical-scale Production of Osteoprogenitor Cells

    SBC: Aastrom Biosciences, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Due to morbidity and limited amounts of material, alternatives to autologous grafts for bone repair are desirable. Cells within the bone marrow are known to possess bone regenerative capacity, but they are limited in number. Increasing these osteoprogenitor cell populations through the use of ex vivo expansion technologies and combining these cells with a matri ...

    SBIR Phase II 2005 Department of Health and Human Services
  2. Clinical Human Cell Production System for Broad Use

    SBC: Aastrom Biosciences, Inc.            Topic: N/A

    The therapeutic potential of patient-specific cultured cells continues to rapidly grow for a range of medical needs, such as regenerative repair of damaged tissue, cancer, and infectious diseases. As a result, the motivation to commercialize patient-specific "cell products" is increasing rapidly as well. A large unmet need exists for the development of reliable clinical and commercial ceil manufac ...

    SBIR Phase II 2005 Department of Health and Human Services
  3. Intelligent Hybrid Power Management Device

    SBC: ADAPTIVE MATERIALS, INC.            Topic: AF05197

    Our goal is to deliver a integrated hybrid power management device to the special operations soldier to minimize the burden of carrying unnecessary weight due to various batteries. Our proposed device includes a programmable voltage output, simple user interface, and a modular design that allows the system to be tailored to specific mission profiles. The system will include an LCD text display t ...

    SBIR Phase I 2005 Department of DefenseAir Force
  4. Novel Routes of Drug Administration to Enhance Compliance in Soldiers

    SBC: ADVANCED SENSOR TECHNOLOGIES, INC.            Topic: A04201

    WHO estimates that between 300 and 500 million new cases of malaria occur each year and annual deaths from the disease number between 2 and 3 million. Although there are several compounds known to be effective for treating malaria, including quinine, doxycycline, primaquine, azithromycin, and erythromycin, side effects associated with the oral administration of these drugs results in incomplete m ...

    SBIR Phase I 2005 Department of DefenseArmy
  5. Transdermal Patch for Pulsatile Nicotine Delivery


    DESCRIPTION (provided by applicant): Current nicotine delivery patches rely on the passive diffusion of nicotine through the skin and into the fluid that surrounds the cells beneath the skin (interstitial fluid). From there, the nicotine diffuses into the capillary network, enters the blood stream, and is delivered to the brain. The nicotine is contained in a textile fiber material within the p ...

    SBIR Phase I 2005 Department of Health and Human Services
  6. A Novel Needle-based X-ray System

    SBC: ADVANCED X-RAY TECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The main objective of this project is to design, fabricate and experimentally research the application of capillary x-ray optics as a means of elevating the dose rate of the radiation produced by a needle-based x-ray system. The goal is to reach the dose rate of 10 Gy/hour at a distance 5 mm from the pseudo-target. The other objective is to apply capillary ...

    SBIR Phase I 2005 Department of Health and Human Services
  7. Detection and Monitoring of Imported Fire Ants Using Remotely Sensed Imagery

    SBC: Automated Decisions, LLC            Topic: N/A

    It is estimated the economic impact (medical, damage, and pesticide costs) of imported fire ants in the infested southern states is in excess of $1 billion annually. Additionally, approximately 30% of all people in the infested regions are stung on an annual basis. Detection of imported fire ants is an important and outstanding problem. This project will develop technology and methodology to detec ...

    SBIR Phase I 2005 Department of Agriculture
  8. Opposed Piston Engine Power Density Improvements

    SBC: BAKER ENGINEERING, LLC            Topic: A03227

    Baker Engineering Inc. proposes opposed-piston engine power density improvements and testing for the SBIR Phase II, DoD Topic #A03-227, contract #W56HZV-04-C-0151. Design improvements, and extensive testing, will be conducted on a 5.8 L demonstrator opposed-piston “Giesel” engine. The 3-cylinder, 2-cycle engine has a target of 600 hp, and weighs less than 1500 lbs. Planned improvements inclu ...

    SBIR Phase II 2005 Department of DefenseArmy
  9. A System for Lengthening Contraction Training of Muscle

    SBC: BIO LOGIC ENGINEERING, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Skeletal muscle atrophy and weakness affects nearly all of the nation's elderly and often leads to frailty, immobility, falls, fractures, and institutionalization. Numerous studies have shown that weight training involving Shortening Contraction Training (SCT) protocols can slow or even reverse this decline. Unfortunately, traditional SCT protocols commonly hav ...

    SBIR Phase I 2005 Department of Health and Human Services
  10. Simulation Algorithms for Spatial Pattern Recognition

    SBC: BIO-ANALYTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This SBIR project is developing methods and software for the specification, construction and simulation of neutral spatial models, and for applying these neutral models within the framework of probabilistic pattern recognition. Results will allow epidemiologists, environmental scientists and image analysts across a broad range of commercial disciplines to m ...

    SBIR Phase II 2005 Department of Health and Human Services

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