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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of a humanized anti-CD47 antibody for treatment of tissue ischemia.

    SBC: VASCULOX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Nitric oxide (NO) is a critical regulator of cardiovascular physiology, coordinating the activities of the endothelium, the vessel wall and circulating cells to optimize the flow of blood and oxygen to tissues. Increasing the bioavailability of NO should provide therapeutic benefit in the treatment of many diseases ascribed to insufficient NO bioavailability. A ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  2. Treatment of Transplant Reperfusion with an Anti-CD47 Antibody

    SBC: VASCULOX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Organ transplantation is one of the great success stories of modern medicine. However, the supply of suitable organs lags far behind the need and many patients die while waitlisted for organs. Current practice involves donor preconditioning to stabilize organs and tissues for transplant in attempts to increase the supply of donor organs acceptable for transpl ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  3. SBIR Phase I: Fabrication of Nanobattery Systems Using Femtosecond Laser Machining

    SBC: US Photonics, Inc            Topic: EL

    This Small Business Innovation Research Phase I research project will use femtosecond laser machining to fabricate Lithium ion based nanobatteries composed of arrays of nanocells. In addition, an array of addressable batteries will also be constructed. A femtosecond laser is a powerful tool to machine features on a variety of materials in the nanoscale regime. These batteries will be grown on flex ...

    SBIR Phase I 2009 National Science Foundation
  4. Residual Stress Measurement and Forecasting System

    SBC: APES INC.            Topic: AF083228

    The proposed approach for Phase I of this effort brings together two key items that are needed to work in concert with one another: advanced fatigue assessment methods and non-destructive inspection & detection techniques. Successful synthesis of these elements and the engineering disciplines behind them will provide an optimized and advanced method of taking full advantage of engineered residual ...

    SBIR Phase I 2009 Department of DefenseAir Force
  5. Verification of Cold Working and Interference Levels at Fastener Holes

    SBC: APES INC.            Topic: AF081088

    The USAF recognizes that benefits to cold working fastener holes include significantly increased life of a structure subjected to fatigue loading. However, full realization of this potential from a maintenance and engineering standpoint is hindered by the fact that there is currently no adequate field technique for determining how well the material structure immediately surrounding the hole has re ...

    SBIR Phase II 2009 Department of DefenseAir Force
  6. Adjunctive Use of Apyrase to Fibrinolytic Therapy

    SBC: APT THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Human apyrase represents a highly promising therapy for treatment of acute myocardial infarction. This enzyme strongly inhibits platelet activation and aggregation with modest bleeding risk. Using a protein informatics approach, we have successfully engineered human apyrases which exhibit both antiplatelet and anti-inflammatory activities. With the Phase I gran ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  7. Apyrase to treat ischemia/reperfusion injury during lung transplantation

    SBC: APT THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Human apyrase represents a highly promising therapy to prevent or reduce ischemia-reperfusion injury during lung transplantation. The enzyme strongly preserves vascular integrity and inhibits platelet activation and aggregation without increasing bleeding risk. Using a protein informatics approach, we have successfully engineered an optimized human apyrase, APT ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  8. Developing an Evidence-Based Intervention Planning System for Obesity Prevention

    SBC: TRANSTRIA, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): To increase the effectiveness of chronic disease prevention and health promotion interventions, researchers and practitioners must work collaboratively to ensure that evidence-based approaches are translated into publicly accessible tools and resources. To disseminate evidence-based intervention strategies, it is essential to summarize the associated processes, ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  9. SBIR Phase I: Heat Spreader Using Nanofluid Oscillating Heat Pipes

    SBC: THERMAVANT TECHNOLOGIES LLC            Topic: EL

    This Small Business Innovation Research (SBIR) Phase I proposal describes a heat spreader embedded with a nanolfuid oscillating heat pipe (OHP) that will meet the cooling needs of high power density electronics by utilizing: 1) the extra-high heat transfer coefficient of thin film evaporation; 2) the elevated thermal conductivities of nanofluids; and 3) the enhanced heat transfer of thermally-exci ...

    SBIR Phase I 2009 National Science Foundation
  10. Hyperspectral and Multi-Modal Retinal Imaging for Assessment of Retinal Laser Damage

    SBC: LICKENBROCK TECHNOLOGIES, INC.            Topic: AF083029

    The Phase I objective is a conceptual design of a hyperspectral/multimodal fundus camera for assessing laser damage.  The premise to be ultimately proven in this project is that damage to the fundus, from laser irradiation, may be characterized and detected by reflectance spectra, and by measuring function such as flow and perfusion.  The system will incorporate an existing fundus camera model ( ...

    SBIR Phase I 2009 Department of DefenseAir Force
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