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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. High-resolution/high-precision PEM Quality Control

    SBC: RESONON, INC.            Topic: C5618h

    High-quality, defect free, and consistent thickness Proton Exchange Membrane (PEM) films are required to ensure maximum efficiency and longevity over the life of hydrogen fuel cells or electrolyzers utilizing this technology. The current technologies of PEM film Quality Assurance (QA) and defect detection rely on human inspection, which can be subjective and labor intensive, or measurement technol ...

    SBIR Phase I 2023 Department of Energy
  2. A low-cost snow water equivalent sensor

    SBC: NWB SENSORS INC            Topic: 84

    Project SummaryAccumulated snowpack is a major source of water throughout the United States. Accuratelymonitoring snow on the northern plains is a significant need for streamflow forecasting andreservoir management. This has been demonstrated by the US Army Corp of Engineersestablishment of the Upper Missouri River Basin Plains Snow and Soil Moisture MonitoringNetwork. The availability of a low-co ...

    SBIR Phase I 2023 Department of Agriculture
  3. Tumor Antigen Targeted Nanoparticle Therapy for Glioblastoma (GBM)

    SBC: NANOVALENT PHARMACEUTICALS INC            Topic: 102

    Project Summary The goal of this Fast Track STTR project is to determine proof-of-principle and efficacy of a novel blood brain barrier (BBB) penetrating therapeutic nanoparticle for the potential treatment of otherwise intractable brain tumors like glioblastoma multiforme (GBM). This project seeks to demonstrate that novel, targetable nanoparticles can delivery therapeutic substances to human bra ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Booth™ by Opio™: Developing technology to expand the reach of opioid treatment programs into rural and underserved areas.

    SBC: Opio Connect, Inc.            Topic: NIDA

    The goal of this project is to develop a treatment booth with technology that allows opioid treatment programs to remotely dispense, either methadone or buprenorphine, under medical observation through telemedicine to a patient in a treatment booth. We believe that robotic automation is the ideal application to perform the same mechanical functions of the nurse at the dosing window. Specifically, ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Pharmacogenomics Workflow: Identifying Biomarkers and Treatment Options

    SBC: Golden Helix, Inc.            Topic: 172

    Abstract Pharmacogenomics, the study of how an individual's genetic makeup affects their response to drugs, has undergone rapid advancements. This has occurred alongside a decrease in the cost of genotyping technology, making implementation of pharmacogenomics into clinical practice increasingly feasible. Personalized medicine leveraging pharmacogenomics is gaining momentum to optimize drug choice ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Selective CYP26 inhibitors for the oral treatment of recalcitrant nodular acne.

    SBC: DERMAXON LLC            Topic: NIAMS

    Project Summary / Abstract DermaXon's project goal is to develop efficacious, substrate-based, selective inhibitors of CYP26s, the enzymes responsible for the metabolism of all-trans retinoic acid (atRA) in the epidermis, as an oral treatment for severe recalcitrant acne. This approach will provide an improved acne therapeutic without the adverse effects associated with currently marketed retinoid ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  7. High-Repetition-Rate Pump Sources Tailored for High-Purity Entanglement Generation

    SBC: ADVR, INC.            Topic: T8

    This Phase I SBIR will lead to the development of a bandwidth tailored pump source for high purity photon pair generation. Spontaneous parametric down conversion can be used to generate high purity photon pairs at wavelengths of interest to NASA and the broader scientific community. However, these sources are highly dependent on pulsed pump laser parameters. Traditional pulsed laser sources are la ...

    STTR Phase I 2023 National Aeronautics and Space Administration
  8. Fault Tolerant RISC-V Flight Computer with Coprocessor Support

    SBC: RESILIENT COMPUTING, LLC            Topic: Z2

    This Phase II project aims to prototype a novel technology that can advance the state-of-the-art in high performance space computing.nbsp; The base computer technology, called ldquo;RadPCrdquo;, brings together a suite of fault recovery mechanisms that enable Commercial-off-the-Shelf (COTS) Field Programmable Gate Arrays (FPGAs) to operate reliably in the presence of space radiation that causes si ...

    SBIR Phase II 2023 National Aeronautics and Space Administration
  9. Real-Time Hardware Configurable Coprocessors

    SBC: RESILIENT COMPUTING, LLC            Topic: Z2

    This project proposes a coprocessor companion to future radiation-hardened processors that can boost performance using commercial Field Programmable Gate Arrays (FPGA). nbsp;This project will investigate the feasibility of using dynamically reconfigurable coprocessing circuitry within a proven fault-tolerant architecture known as RadPC.nbsp; The RadPC architecture has been matured through NASA-fun ...

    SBIR Phase I 2023 National Aeronautics and Space Administration
  10. Visible light phase and amplitude modulators for quantum sensors and clocks

    SBC: ADVR, INC.            Topic: S16

    This Phase I SBIR will lead to the development of key photonic components for use in high performance quantum sensors and clocks. AdvR proposes to develop very high performance phase and amplitude modulators for use at visible and ultra-violet wavelengths. The proposed innovation utilizes high performance, damage resistant optical waveguides with high speed traveling wave electrodes to provide int ...

    SBIR Phase I 2023 National Aeronautics and Space Administration
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