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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1 - 10 of 5662 results
  1. Instrument for Characterization of Off-axis Direct and Ultraviolet Scatter (CODUS) for the Joint Standard Instrumenation System (JSIS)

    SBC: SCITEC INC            Topic: MDA04010

    The purpose of the present effort is to provide a capability to the Joint Standard Instrumentation Suite (JSIS) for the characterization of ultraviolet atmospheric scattering in order to better determine the impact of atmospheric absorption/scattering on missile signatures.A working prototype of the Characterization of Off-axis Direct and Ultraviolet Scatter (CODUS) instrument will be built and de ...

    SBIR Phase II 2018 Department of DefenseAir Force
  2. Prediction of the Full-Scale Cook-off Response Based on Small-Scale Testing

    SBC: BLAZETECH CORPORATION            Topic: N10AT011

    Reducing the violence of Slow Cook-Off (SCO) and Fast Cook-Off (FCO) to acceptable levels is of great interest to the Insensitive Munitions development. For example, the MIL-STD-2105C SCO test for Insensitive Munitions (IM) compliance requires a slow heating rate (3.3°C/hr) until reaction occurs whereby the ensuing reaction is characterized by degree of violence. A Type V (burn) reaction or bette ...

    STTR Phase II 2018 Department of DefenseNavy
  3. Adaptive Clinical Efficacy Evaluation of ONC201 in Recurrent High Grade Glioma

    SBC: Oncoceutics, Inc.            Topic: 102

    Project Summary We propose a two-arm adaptive Phase II clinical trial to evaluate ONC201, a selective antagonist of the G protein-coupled receptor (GPCR) dopamine receptor domain 2 (DRD2), in recurrent glioblastoma (GBM) and diffuse midline glioma associated with very poor prognoses and limited treatment options. DRD2 is overexpressed in high grade gliomas and controls Akt/ERK signaling pathways. ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. sHLA Protein Chip

    SBC: GENOMICS USA, INC.            Topic: NIAID

    Abstract: “sHLA Protein Chip” The class I [A, B, C] and class II HLA proteins [DRB1, DQ, DP] comprise the heart of the inducible human immune system. For organ, marrow and stem cell transplantation, the development of serum-born antibodies against one or more of those many HLA proteins comprises the best and earliest test for transplant rejection. Because of the enormous medical importance of ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Automated Harness Tightener for Child Safety Seat

    SBC: Minnesota HealthSolutions Corporation            Topic: NICHD

    Project Summary Abstract Motor vehicle crashes are the leading cause of unintentional morbidity and mortality among children in the United States and a leading cause of brain injuryBrain injuries resulting from the child s head impacting surfaces in the vehicle during a frontal crash are a significant problem and head injury is the leading cause of death and serious injury for children in crashesC ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Automating mosquito microdissection for a malaria PfSPZ vaccine

    SBC: SANARIA INC.            Topic: R

    ABSTRACTThe global death toll from Malaria is estimated to be upwards ofpeople each yearwith more thanchildren succumbing every dayPlasmodium falciparumPfSporozoiteSPZbased vaccines are the only intervention in humansproven to induce robusthigh levelandgtand long lastingat leastmonthsprotective efficacy against malariaforming the basis of Sanaria s unique technology platform of asepticpurifiedcryo ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. A Novel Device for Ultra-Rapid Non-Pharmacologic Ocular Anesthesia

    SBC: Irenix Medical, Inc.            Topic: NEI

    PROJECT SUMMARY / ABSTRACTThe objective of this Phase II proposal is to further develop a novel device for ocular anesthesia based on thermo-electric cooling. Intravitreal injection therapy (IVT) is one of the most commonly performed procedures in all of medicine, with approximately 7 million injections in the USA in 2016. Ocular anesthesia is required, both for patient safety and for tolerability ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Nezavist a Novel Molecule for Treatment of Alcohol Use Disorder

    SBC: LOHOCLA RESEARCH CORPORATION            Topic: 150

    Abstract for Supplement ApplicationThe ultimate goal for our original project was to complete the proof-of-concept work, and the multitude of pharmacodynamic, pharmacokinetic, toxicokinetic, safety, and toxicology studies required by the FDA to apply for an IND. We are fully satisfied that we have generated a new chemical entity that acts at a novel binding site on the GABA-A receptor and acts in ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Improving drug safety for pregnant women by delivering current and authoritative information via mobile devices

    SBC: RightAnswer.Com, Inc.            Topic: NCBDDD

    Project SummaryAbstract! An!estimated!!infants!delivered!annually!in!the!United!States!are!born!with!birth!defects!caused!by!the!use!of! medication!during!pregnancy !!Since!the!peak!prevalence!of!some!diseases !such!as!hypertension !autoimmune!disease ! and!depression !occurs!during!the!childbearing!years !it!is!not!surprising!that!medication!use!during!pregnancy!is! common !with!nine!out!of!ten!p ...

    SBIR Phase II 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  10. Topic 368: Biotherapy of Brain Tumors by Radioiodinated SapC-DOPS Nanovesicles

    SBC: MOLECULAR TARGETING TECHNOLOGIES, INC.            Topic: NCI

    There is an urgent need for more effective drug delivery agents for treatment of brain tumors, which are among the most aggressive and intractable cancers. SapC-DOPS, a nanovesicle composed of saposin C (SapC) coupled to dioleoylphosphatidylserine (DOPS), has proven tumor targeting properties, which include crossing the blood-brain tumor barrier and binding the lipid tumor marker, extracellular ph ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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