Award Data

DESCRIPTION provided by applicant Many patients requiring stem cell transplantation for hematological malignancies are unable to find a suitable HLA matched sibling or unrelated donor Transplants using stem cells from umbilical cord blood provide an alternative for these patients allowing transplantation to proceed with less stringent HLA matching requirements Unfortunately in addition to t ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project is the development of technology for use of sulfide mining waste streams as a novel energy source for the production of chemicals from CO2. Sulfide mining wastes pose a serious, perpetual environmental risk, and are continuously generated as by-products of mining operations. The sulfide minerals in mi ...

The broader impact/commercial potential of this Small Business Innovation Research Phase I project is opening a new, low-temperature range of Diesel emission control currently unavailable, while providing further flexibility in Diesel vehicle performance significant for commercial vehicles particularly those in stop-and-go operations (city-type duty cycles). Its environmental and societal impacts ...

This Small Business Innovation Research Phase I project will support the development of a confocal optical microscope with two-dimensional topographical profiling and multiple spectroscopic modes in a single, affordable precision instrument. The system will make a major impact in the $6.2 billion microscope market, with a near-term market penetration potential of over 5%, and significant growth po ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is that it will for the first time make it possible to create voice technologies whose performance in speech and speaker recognition does not significantly degrade due to the presence of interfering voices or environmental sounds. This issue has kept many voice technologies out of both the mob ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project involves a disruptive change to the solar energy industry by potentially doubling the efficiency of the best available solar cells while, at the same time, significantly reducing their cost. Renewable energy sources are critical to energy independence and, importantly, to the long-term viabili ...

This SBIR Phase I project seeks to develop a novel low-cost molecular filter for use in harsh environments. This is accomplished using commodity silica gel, commonly found as a desiccant in food packing, whose pores can be made to be only a few molecules wide. Accurate tuning of the size and shape of the silica gel pores enables certain molecules to pass through while others are block from passing ...

The broader impact/commercial potential of this Small Business Innovation Research Phase I project includes the development of new methods to biodegrade waste plastics. Plastic waste is an significant environmental burden. Over 300 million tons of plastic are used each year, resulting in millions of tons of persistent plastic waste, some of which can take up to 600 years to degrade. Mealworms (Ten ...

This project will develop an immersive and dynamic multi-player game that addresses a pressing need to provide engaging technologies that prepare students to apply collaborative, cross-disciplinary scientific practices to global societal challenges. In an augmented classroom with their real life peers, students must establish a colony on Mars that is capable of sustaining thousands of refugees fro ...

This STTR Phase I project aims to establish the viability of a drug delivery platform that employs an engineered strain of Staphylococcus (S.) epidermidis, a common skin commensal bacterium, that can secrete therapeutic proteins of interest for the ultimate goal of treating skin disease. An ointment with an inoculum of such bacteria could be infrequently applied to skin, providing constant, low-co ...