Award Data

We propose to prototype an open, modular, UUV Operational Digital Twin called the Remote Operational Monitoring Unit Leveraging UUV Simulation, or “ROMULUS.” An Operational Digital Twin is a virtual representation of a UUV and its environment that is based on physics-based models and machine learning that continuously integrates data from a priori sources, the mission plan (MP), onboard sensor ...

Integer Technologies LLC proposes to develop a set of operational digital twins that run in parallel both onboard and offboard an unmanned underwater vehicle (UUV) called the Remote Operational Monitoring Unit Leveraging UUV Simulation, or “ROMULUS.” ROMULUS is designed to provide the UUV Operator with continuous high-fidelity situational awareness of what their UUVs are doing, even during tim ...

Ocular traumas resultingfrom explosive or incendiary devices arecommon battlefield injuries. Current therapeutics do not address the biological and molecular processes in corneal wound healing, and therapeuticfailureis associated with corneal ulcers,scarring, and vision loss. Ocular therapeutics that haveregenerative healing properties and restorecorneal biomechanical integrity and can bereadily a ...

In this Phase II work program, Mission Solutions Group will develop and deliver to USSOCOM a software prototype system for the Platform Agnostic Data Storage Infrastructure (PADSI) Small Business Innovation Research (SBIR) program. Our technical solution is designed to provide a common framework for multi-model, multi-layer data storage and import/export control as well as advanced Artificial Inte ...

Non-oxide based ceramic matrix composites (CMCs), such as Silicon Carbide and Carbon-Carbon, are current state-of-the-art (SOA) refractory thermal protection system (TPS) materials for space reentry vehicle leading edge components and hot structures that...

Vitrification, cryopreserved storage in a “glassy” rather than crystalline phase, is an important enabling approach for tissue banking and regenerative medicine, offering the ability to store and transport cells, tissues and organs for a variety of biomedical uses without the risks of damaging ice formation. Unfortunately, practical application of vitrification has been limited to reproductive ...

We will evaluate a novel warming method, developed by our collaborator John Bischof, that promises solution of one of the remaining barriers for banking of large organs and vascularized composite tissues. The method involves radiofrequency and magnetic nanoparticles to obtain rapid uniform electromagnetic rewarming of biological materials instead of warming from the outer boundary using convection ...

The long term goal of the proposed research is to develop improved methods for cryopreservation of complex tissues at extreme low temperature. An innovative approach is taken in the proposed line of research, where synthetic ice modulators (SIMs) are combined with established cryoprotective agent (CPA) cocktails to create more favorable conditions for cryopreservation in a process known as vitrifi ...

Purpose: For most of the 20th century, students with visual impairments were placed in separate schools from their peers. With major advances in public policy, it is now more common that all students (regardless of such disabilities) be integrated within schools and in classrooms. Recent research demonstrates a lack of products to support the visually impaired in STEM (science, technology, enginee ...

Purpose: With national attention on the shortage of STEM (science, technology, engineering, and mathematics) professionals, enrollment in science is expected to be on the rise in the years to come. Laboratory work is seen as an essential part of many STEM courses, because labs enable students to interact with natural phenomena and analyze collected data. Funding adequate labs, however, has become ...