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Basic science discoveries have led to the development of a series of human biotherapeutic drugs for the treatment of cancer and HIV as well as many other diseases. Currently there are over 400 drugs in clinical trials just for the first two diseases. The current biotherapeutics' manufacturing platforms have not kept pace resulting in a dramatic rise in treatment cost and more importantly unmet the ...

Overabundance of fiber from young trees derived from first thinnings with little or no market is a serious problem for the timber industry as well as private landowners. Because of this, many private landowners fail to conduct appropriate timber management which in turn causes reductions in stand volume, increased risk of insect and/or disease from reduced stand vigor, reduced browse for wildlife ...

Removal and disposal of agricultural mulch films made from polyethylene requires large expenditures of time and money, and creates excessive demand for landfill space. The purpose of this project is to create agricultural mulch films from renewable resources that can be incorporated into the soil for disposal rather than being landfilled.

IN CURRENT AGRICULTURAL SPRAYING, LESS THAN 20% OF PESTICIDEREACHES THE INTENDED PLANT; MOST DRIFTS OR DEPOSITS ON THE SOIL, RESULTING IN ECONOMIC LOSS AND ENVIRONMENTAL HAZARD. SPRAY REACHING PLANTS IS OFTEN WASTED BECAUSE OF POOR PLACEMENT OF DROPLETS. EXCESS PESTICIDE DEPOSITS ARE PLACEDON UPPER LEAF SURFACES, AND LOWER CANOPY REGIONS RECEIVE INSUFFICIENT DOSAGES. LESS THAN 1% OF APPLIED SPRAY ...

This Small Business Innovation Research (SBIR) Phase II project addresses the impact of product variety on the customer order fulfillment process. It aims to help the manufacturers of highly configurable products with many possible "variants" or "configurations" to maximize product availability and order fill rates. Prior research by Emcien has created a methodology for representing product varia ...

This Small Business Innovation Research (SBIR) Phase I project addresses the impact of product variety on parts inventories. The goal is to help the manufacturers of configurable products; these are products that have many different configurations, or variants, or build combinations. These variants arise because the product has a large number of features/options or the customer is given choices ov ...

Bacillus thuringiensis (Bt) biopesticides are an environmentally safe alternative to chemical pesticides but less efficacious than chemical alternatives. The purpose of this study is to determine the suitability of BtBooster in improving Bt biopesticides so that it as good as or better than the more efficacious chemical alternatives.

This Small Business Innovation Research (SBIR) Phase II project will further develop a new Flow Path Management System (FPMS) representing an innovation in manufacturing software that: (1) Extends existing Enterprise Resource Planning (ERP), Supply Chain Management (SCM), and Manufacturing Execution Systems (MES) software by incorporating 'Lean Manufacturing' principles into a set of innovative si ...

This Small Business Innovation Research (SBIR) Phase I project will investigate three-phase nanocomposite films for embedded capacitor applications. There is demand for an embedded capacitor technology that addresses the need for miniaturization and increased functionality of electronic systems. The proposed three phase nanocomposite artificial dielectrics have the potential to have high dielectri ...