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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Development of a Simple, Quantitative Kit to Test Vegetables and Fruits for Evidence of Fecal Contamination

    SBC: SCIENTIFIC METHODS INC            Topic: N/A

    One of the most vulnerable sectors in the food industry includes "ready-to-eat" fruits and vegetables that may be consumed without peeling, pasteurization, or cooking. Increases in the year-round consumption of fresh fruits and vegetables that are out of season in the United States, coupled with the relaxation of international trade restrictions, have resulted in significant increases in the impor ...

    SBIR Phase II 2006 Department of Agriculture
  2. SoundAlert- A Centralized System Capable of Alerting People Who are Deaf or Hard of Hearing Impaired of Critical Sounds in Their Environment

    SBC: CREATEABILITY CONCEPTS, INC.            Topic: N/A

    The project is intended to result in a comprehensive system that delivers natural warning and communication mechanisms for persons with hearing loss. The SoundAlert system offers a unique approach to enable persons who are deaf or hard of hearing to: (1) initiate and receive emergency communications; (2) receive alerts in the workplace or home environments on a single, pocket-sized device throug ...

    SBIR Phase II 2006 Department of Education
  3. Movement-Responsive Cage for Simultaneous Pharmacology Studies in MiniPigs

    SBC: Bioanalytical Systems, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Animal models for human disease are important tools for biomedical and pharmaceutical research. Pigs, like humans, develop hypertension, diabetes and cardiovascular disease and respond to stress by releasing hormones via the HPA axis. We propose to utilize pigs more effectively and humanely, by allowing multiple experiments to be conducted simultaneously in the ...

    SBIR Phase I 2006 Department of Health and Human Services
  4. HIFU and Immunotherapy Treatment of Metastatic Prostate Cancer

    SBC: FOCUS SURGERY INC            Topic: N/A

    DESCRIPTION (provided by applicant): Past experimental investigations have demonstrated that the application of HIFU (High Intensity Focused Ultrasound) to cancerous tumors results in the release of heat shock proteins and a beneficial immunizing effect. The release of proteins into the blood as a result of HIFU therapy is further demonstrated by the spike of the serum prostate specific antigen (P ...

    SBIR Phase I 2006 Department of Health and Human Services
  5. AUTOMATED CLOSED SYSTEM FOR DMSO REMOVAL FROM PERIPHERAL BLOOD STEM CELLS

    SBC: GENERAL BIOTECHNOLOGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): High dose chemotherapy followed by peripheral blood hematopoietic stem cell (PBSC) transplantation is frequently used for treating various hematologic malignancies. To facilitate this process, autologous PBSC are typically collected, cryopreserved and stored for some period of time. Current PBSC cryopreservation requires the use of molar concentrations of the c ...

    SBIR Phase I 2006 Department of Health and Human Services
  6. HAZMAT Training Using a Problem-based Methodology and Serious Games Approach

    SBC: WisdomTools Enterprises Inc            Topic: N/A

    DESCRIPTION (provided by applicant): HAZMAT response teams operate in increasingly cognitively complex, mentally stressing, physically fatiguing, and dangerous environments. Yet training needs need to include faster and direct access to new technologies, more operations-level training for first responders, and to provide hands-on and in simulated settings. This Phase I effort seeks to address this ...

    SBIR Phase I 2006 Department of Health and Human Services
  7. Non-instrumented Device for Diabetic/Vascular Risk S

    SBC: MICRONIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): More than half of the world's diabetics and individuals at risk for atherosclerosis due to high blood glucose and lipids (cholesterol, triglyceride) are undiagnosed. A fast growing component of this huge patient population are people with metabolic syndrome. Most of these subjects are generally unaware and thus deprived of the proven benefits of tight glucose c ...

    SBIR Phase I 2006 Department of Health and Human Services
  8. PI-Fish: A Novel approach for discovering druggable sites in cancer proteins

    SBC: Molecular Kinetics Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Project Summary. In the predominant sequence-to-function paradigm, 3-D structure is an obligatory . prerequisite for protein function. This paradigm dominates thinking about drug discovery. Even though over 100 counter examples not following this paradigm are described in literature, the functions associated with these non-folded (disordered) protein has been m ...

    SBIR Phase I 2006 Department of Health and Human Services
  9. In vivo Thermoacoustic Imaging of HER2 Status

    SBC: OPTOSONICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): In this Fast Track application, we propose developing the novel imaging technology and molecular probe that will enable the non-invasive detection and quantification of HER2 overexpression in breast cancers. The approach we are promoting is to label Herceptin, a therapeutic mono-clonal antibody, with an infraredabsorbing dye, and then to detect the presence ...

    SBIR Phase II 2006 Department of Health and Human Services
  10. Development of Force Based Orthodontic Appliances

    SBC: OSCAR, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The proposed project will develop a series of new orthodontic appliances using a patented technology. Using the appliances, clinicians will be able to quantify and manipulate the orthodontic force systems, which are not feasible at present. The ability to control the force system is essential for the advancement of orthodontical treatment. It enables the orthod ...

    STTR Phase I 2006 Department of Health and Human Services

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